Fukuchi Yumi

フクチユミ | Fukuchi Yumi

Affiliation and department：
Homepage URL (1)： https://kaken.nii.ac.jp/d/r/40250237.ja.html

Research field (2)： Laboratory animal science , Hematology and oncology

Research keywords (3)： Graves' disease , acute myeloid leukemia , hematopoietic stem/progenitor cells

Research theme for competitive and other funds (4)：

1999 - 2000 アクチビンAによる慢性骨髄性白血病の分化/アポトーシス誘導の増殖抑制機構
1999 - 2000 Mechanisms of apoptosis and differentiation induced by arsenic trioxide in leukemic cells and its clinical application
1997 - 1998 ヒト造血系維持モデルとしてのヒトSCF遺伝子導入-SCIDマウスの検討
1996 - 1996 ヒト造血系細胞維持モデルのためのヒトSCF遺伝子導入マウスの作製

Papers (39)：

Takatsune Shimizu, Atsunobu Sagara, Yumi Fukuchi, Akihiro Muto. Single-agent nintedanib suppresses metastatic osteosarcoma growth by inhibiting tumor vascular formation. Oncology Letters. 2024. 27. 3
Shunsuke Soma, Koichi Murakami, Yumi Fukuchi, Hiroyoshi Kunimoto, Hideaki Nakajima. O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2023
Takatsune Shimizu, Eiji Sugihara, Hideyuki Takeshima, Hiroyuki Nobusue, Rui Yamaguchi, Sayaka Yamaguchi-Iwai, Yumi Fukuchi, Toshikazu Ushijima, Akihiro Muto, Hideyuki Saya. Depletion of R270C Mutant p53 in Osteosarcoma Attenuates Cell Growth but Does Not Prevent Invasion and Metastasis In Vivo. Cells. 2022. 11. 22
Takatsune Shimizu, Kiyomi Kimura, Eiji Sugihara, Sayaka Yamaguchi-Iwai, Hiroyuki Nobusue, Oltea Sampetrean, Yuji Otsuki, Yumi Fukuchi, Kaori Saitoh, Keiko Kato, et al. MEK inhibition preferentially suppresses anchorage-independent growth in osteosarcoma cells and decreases tumors in vivo. Journal of Orthopaedic Research. 2021
Koichi Murakami, Daisuke Kurotaki, Wataru Kawase, Shunsuke Soma, Yumi Fukuchi, Hiroyoshi Kunimoto, Ryusuke Yoshimi, Shuhei Koide, Motohiko Oshima, Takako Hishiki, et al. OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy. Cell reports. 2021. 34. 1. 108579-108579

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MISC (19)：

Koichi Murakami, Daisuke Kurotaki, Wataru Kawase, Shunsuke Soma, Yumi Fukuchi, Hiroyoshi Kunimoto, Ryusuke Yoshimi, Shuhei Koide, Motohiko Oshima, Takako Hishiki, et al. Regulation of Mitophagy By O-Linked N-Acetylglucosamine Transferase Is Essential for Hematopoietic Stem Cell Maintenance. BLOOD. 2018. 132
村上紘一, 黒滝大翼, 川瀬航, 相馬俊介, 福地由美, 國本博義, 吉見竜介, 小出周平, 大島基彦, 小田真由美, et al. O-GlcNAc化による造血幹細胞ミトコンドリアダイナミクスの制御(O-GlcNAcylation is critical for mitochondrial dynamics in hematopoietic stem cells). 臨床血液. 2018. 59. 9. 1483-1483
S. Soma, Y. Fukuchi, S. Okamoto, H. Nakajima. A CRITICAL ROLE FOR O-GLCNACYLATION IN MURINE FETAL LIVER AND ADULT HEMATOPOIESIS. HAEMATOLOGICA. 2015. 100. 125-126
Hiroyoshi Kunimoto, Yumi Fukuchi, Masatoshi Sakurai, Daichi Abe, Ken Sadahira, Yasuo Ikeda, Shinichiro Okamoto, Hideaki Nakajima. Tet2 Uniquely Regulates Self-Renewal and Long Term Repopulating Capacity of Fetal Liver and Bone Marrow Hematopoietic Stem Cells. BLOOD. 2012. 120. 21
Masatoshi Sakurai, Hiroyoshi Kunimoto, Naohide Watanabe, Yumi Fukuchi, Ken Sadahira, Shinsuke Yuasa, Keiichi Fukuda, Satoshi Yamazaki, Hiromitsu Nakauchi, Yasuhiro Ebihara, et al. Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML. BLOOD. 2012. 120. 21

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Education (3)：

Professional career (1)：

Work history (8)：

2011/06 - 現在 Hoshi University Department of Pathophysiology, School of Pharmacy and Pharmaceutical Sciences Assistant Professor
2008/02 - 2011/05 Keio University School of Medicine Division of Hematology, Department of Internal Medicine Researcher
2003/04 - 2008/01 the University of Tokyo Division of Cellular Therapy (Kitamura Lab.), Institute of Medical Science Researcher
2001/05 - 2003/03 the University of Tokyo Division of Cellular Therapy (Tsuji Lab.), Institute of Medical Science, Researcher
1998/04 - 2001/04 Department of Internal Medicine, Keio University School of Medicine Division of Hematology Researcher

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Awards (3)：

2005/12 - the American Society for Hematology Travel Award of the American Society for Hematology
2005/10 - the Japanese Society for Hematology Incitement Award of the Japanese Society for Hematology
2004/12 - the American Society for Hematology Travel Award of the American Society for Hematology

Association Membership(s) (1)：

THE JAPANESE SOCIETY OF HEMATOLOGY

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