Art

J-GLOBAL ID：202102228726016555   Reference number：21A0212422

OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy

OGTはPINK1依存性マイトファジーを介して造血幹細胞維持を調節する【JST・京大機械翻訳】

Author (30)： Murakami Koichi (Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Murakami Koichi (Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan) ,  Murakami Koichi (Advanced Medical Research Center, Yokohama City University, Yokohama 236-0004, Japan) ,  Kurotaki Daisuke (Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan) ,  Kawase Wataru (Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan) ,  Soma Shunsuke (Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Fukuchi Yumi (Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Kunimoto Hiroyoshi (Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan) ,  Yoshimi Ryusuke (Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan) ,  Koide Shuhei (Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan) ,  Koide Shuhei (Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8039, Japan) ,  Oshima Motohiko (Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan) ,  Oshima Motohiko (Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8039, Japan) ,  Hishiki Takako (Clinical and Translational Research Center, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Hishiki Takako (Department of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Hayakawa Noriyo (Clinical and Translational Research Center, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Matsuura Tomomi (Clinical and Translational Research Center, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Oda Mayumi (Department of Systems Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Yanagisawa Kiichi (Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan) ,  Kobayashi Hiroshi (Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan) ,  Haraguchi Miho (Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan) ,  Atobe Yoshitoshi (Department of Neuroanatomy, Yokohama City University School of Medicine, Yokohama 236-0004, Japan) ,  Funakoshi Kengo (Department of Neuroanatomy, Yokohama City University School of Medicine, Yokohama 236-0004, Japan) ,  Iwama Atsushi (Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan) ,  Iwama Atsushi (Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8039, Japan) ,  Takubo Keiyo (Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan) ,  Okamoto Shinichiro (Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Tamura Tomohiko (Advanced Medical Research Center, Yokohama City University, Yokohama 236-0004, Japan) ,  Tamura Tomohiko (Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan) ,  Nakajima Hideaki (Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan)
Material： Cell Reports
Volume： 34  Issue： 1  Page： Null  Publication year： 2021 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： O-linked N-acetylglucosamine (...

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Thesaurus term： enzyme ,  transferase ,  mitochondria ,  *hematopoietic stem cell ,  active oxygen ,  apoptosis ,  knockout mouse
Semi thesaurus term： ストレス応答 ,  調節因子 ,  前駆細胞 ,  標的蛋白質 ,  *マイトファジー ,  細胞型 ,  過剰発現 , 【Automatic Indexing@JST】

Author keywords (8)： O-linked N-acetylglucosamine transferase ,  OGT ,  O-GlcNAcylation ,  hematopoietic stem cell ,  hematopoietic progenitor cell ,  mitochondria ,  mitophagy ,  PINK1

JST classification (2)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Terms in the title (5)： PINK1 ,  依存性 ,  マイトファジー ,  造血幹細胞 ,  調節