Nagaoka Katsuya

ナガオカカツヤ | Nagaoka Katsuya

Affiliation and department：

Research field (3)： Cell biology , Medical biochemistry , Gastroenterology

Research keywords (8)： Histone demethylases , Metabolome , MicroRNA , Antibody drug conjugate , Molecular Targeted therapy , KDM1 , Fatty acids , Epigenetics

Research theme for competitive and other funds (7)：

2022 - 2025 Elucidation of the resistance mechanism to chemotherapy in biliary tract and pancreatic cancer by focusing on energy-metabolizing coenzymes
2021 - 2024 栄養環境がもたらすエピゲノム制御変化の解明に基づく肝発癌増殖進展の制御
2020 - 2024 Analysis of epigenome and metabolic phenotypes in Thai liver fluke-associated cholangiocarcinoma
2019 - 2022 Basic research and Clinical Application of Hepatocellular Carcinoma Therapy by Interaction of Epigenetic Drugs and Environmental Factors
2018 - 2021 Analysis of metabolic reprogramming induced by cellular environment and its application to control hepato-carcinogenesis

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Papers (38)：

Xian-Yang Qin, Yohei Shirakami, Masao Honda, Shiou-Hwei Yeh, Kazushi Numata, Ya-Yun Lai, Chiao-Ling Li, Feifei Wei, Yali Xu, Kenji Imai, et al. Serum MYCN as a predictive biomarker of prognosis and therapeutic response in the prevention of hepatocellular carcinoma recurrence. International journal of cancer. 2024
Takehisa Watanabe, Sanae Hayashi, Yan Zhaoyu, Hiroki Inada, Katsuya Nagaoka, Masakuni Tateyama, Yasuhito Tanaka. A novel, small anti-HBV compound reduces HBsAg and HBV-DNA by destabilizing HBV-RNA. Journal of gastroenterology. 2024
Takanori Suzuki, Kentaro Matsuura, Yoshihito Nagura, Hayato Kawamura, Kei Fujiwara, Shintaro Ogawa, Katsuya Nagaoka, Etsuko Iio, Takehisa Watanabe, Hiromi Kataoka, et al. Serum angiopoietin-2 levels predict the development of hepatocellular carcinoma following hepatitis C virus eradication using direct-acting antiviral agents. Oncology. 2024
Takehisa Watanabe, Katsuya Nagaoka. An RNA-degrading enzyme emerges as biomarker study of human hepatitis virus B. Hepatology Research. 2023. 54. 3. 220-221
Takanori Suzuki, Kentaro Matsuura, Yuta Suzuki, Fumihiro Okumura, Yoshihito Nagura, Satoshi Sobue, Sho Matoya, Tomokatsu Miyaki, Yoshihide Kimura, Atsunori Kusakabe, et al. Serum CXCL10 levels at the start of the second course of atezolizumab plus bevacizumab therapy predict therapeutic efficacy in patients with advanced BCLC stage C hepatocellular carcinoma: A multicenter analysis. Cancer medicine. 2023. 13. 1

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MISC (133)：

Katsuya Nagaoka, Yasuhito Tanaka, Okio Hino. The Tumor Microenvironment in Hepatocellular Carcinoma. Interdisciplinary Cancer Research. 2022
Katsuya Nagaoka, Chengcheng Ji, Xuewei Bai, Kevin Cao, Joud Mulla, Amalia Bay, William Mueller, Grace Hildebrand, Yasuhito Tanaka, Jack R. Wands, et al. ELEVATED 2-OXOGLUTARATE ANTAGONIZES CHEMOTHERAPEUTIC EFFECTS IN CHOLANGIOCARCINOMA BY TARGETING DNA DAMAGE RESPONSE SIGNALING PATHWAYS. HEPATOLOGY. 2021. 74. 687A-688A
Satoshi Narahara, Takehisa Watanabe, Kentaro Tanaka, Hiroki Inada, Sotaro Kurano, Takayuki Tokunaga, Yoko Yoshimaru, Katsuya Nagaoka, Hiroko Setoyama, Masakuni Tateyama, et al. NOVEL SERUM BIOMARKERS USEFUL FOR DRUG SELECTION OF SORAFENIB AND LENVATINIB FOR HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2021. 74. 658A-659A
Takayuki Tokunaga, Hiroki Inada, Kentaro Tanaka, Yoko Yoshimaru, Satoshi Narahara, Katsuya Nagaoka, Takehisa Watanabe, Masakuni Tateyama, Yasuhito Tanaka. OPTIMAL STRATEGY OF 1st OR LATER-LINE LENVATINIB THERAPY FOR PATIENTS WITH UNRESECTABLE HEPATOCELLULAR CARCINOMA BY FOCUSING ON EARLY-PHASE RELATIVE DOSE INTENSITY. HEPATOLOGY. 2021. 74. 659A-659A
立山雅邦, 田中健太郎, 楢原哲史, 徳永尭之, 川崎剛, 長岡克弥, 吉丸洋子, 渡邊丈久, 田中靖人. 肝硬変症例における潜在性肝性脳症に対する体組成の関連についての検討. 肝臓. 2021. 62. Suppl.1. A337-A337

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Books (2)：

薬剤性消化器疾患の治療 (3) 肝臓『臨牀消化器内科 Vol.35 No.7(3-3)』
株式会社日本メディカルセンター 2020
薬物性肝障害『1336専門家による私の治療』
日本医事新報社 2017

Education (2)：

2009 - 2013 Kumamoto University Graduate School of Medical Sciences Gastroenterology and Hepatology
1995 - 2002 Miyazaki Medical College

Professional career (1)：

Ph.D. (Medical Science) (Kumamoto University)

Work history (7)：

2023/05 - 現在 Kumamoto University Hospital Gastroenterology and Hepatology Assistant Professor
2021/01 - 2023/04 Kumamoto University Hospital Gastroenterology and Hepatology Assistant Professor
2019/04 - 2020/12 Kumamoto University Hospital Gastroenterology and Hepatology Specially Appointed Assistant Professor (Full time)
2018/04 - 2019/03 Kumamoto University Hospital Gastroenterology and Hepatology Staff clinician
2016/04 - 2018/03 Brown University & Rhode Island Hospital Liver research center Postdoctoral research associate

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Association Membership(s) (6)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPAN SOCIETY OF CLINICAL ONCOLOGY , JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY , THE JAPAN SOCIETY OF HEPATOLOGY , JAPANESE SOCIETY OF GASTROENTEROLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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