Rchr
J-GLOBAL ID：201601020871638785
Update date: Oct. 31, 2024
Torisawa Yu-suke
Torisawa Yu-suke
Affiliation and department：
Research field (3)：
Nano/micro-systems
, Biomaterials
, Biomedical engineering
Research keywords (5)：
Organs-on-Chips
, Stem Cell Biology
, bio-MEMS
, Tissue Engineering
, Microfluidics
Research theme for competitive and other funds (3)：
- 2020 - 2021 Development of a 3D tumor-on-a-chip platform for cancer immunotherapy
- 2017 - 2020 Development of patient-derived cancer on-a-chip devices for cancer immunotherapy
- 2016 - 2018 Development of a microfluidic device to mimic the function of the thymus for immunotherapy
Papers (50)：
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Sayaka Deguchi, Kaori Kosugi, Naoki Takeishi, Yukio Watanabe, Shiho Morimoto, Ryosuke Negoro, Fuki Yokoi, Hiroki Futatsusako, May Nakajima-Koyama, Mio Iwasaki, et al. Construction of multilayered small intestine-like tissue by reproducing interstitial flow. Cell stem cell. 2024
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Sayaka Deguchi, Kaori Kosugi, Rina Hashimoto, Ayaka Sakamoto, Masaki Yamamoto, Rafal P Krol, Peter Gee, Ryosuke Negoro, Takeshi Noda, Takuya Yamamoto, et al. Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips. PNAS nexus. 2023. 2. 3. pgad029
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Mengyang Wang, Masahiro Tsuda, Sayaka Deguchi, Yuriko Higuchi, Kanako So, Yu-Suke Torisawa, Kazuo Takayama, Fumiyoshi Yamashita. Application of perfluoropolyether elastomers in microfluidic drug metabolism assays. International journal of pharmaceutics. 2022. 627. 122253-122253
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Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, Risa Funatsu, Kaori Kosugi, Sayaka Deguchi, Masaki Yamamoto, Yugo Tsunoda, Maaya Morita, Kosuke Muraoka, et al. SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression. Science advances. 2022. 8. 38. eabo6783
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Yuko Sasaki, Hirotaka Tatsuoka, Masahiro Tsuda, Takumi Sumi, Yuka Eguchi, Kanako So, Yuriko Higuchi, Kazuo Takayama, Yusuke Torisawa, Fumiyoshi Yamashita. Intestinal Permeability of Drugs in Caco-2 Cells Cultured in Microfluidic Devices. Biological & pharmaceutical bulletin. 2022. 45. 9. 1246-1253
ｍore...
MISC (20)：
Patents (1)：
Books (4)：
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Microfluidic organs-on-chips to reconstitute cellular microenvironments
(Springer) Applications of Microfluidic Systems in Biology and Medicine 2019
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マイクロエンジニアリング技術を用いた生体模倣デバイスの開発
(医歯薬出版) 歯科再生医学 2019
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骨髄機能の再現に向けたOrgan-on-a-chip
(シーエムシー出版) 臓器チップの技術と開発動向 2018
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マイクロフルーイディックシステムを用いた細胞デバイス
(テクノシステム) バイオセンサ・ケミカルセンサ事典 2007
Education (2)：
- - 2006 Tohoku University Graduate School of Environmental Studies
- - 2001 Tohoku University School of Engineering Biomolecular Engineering
Professional career (1)：
Work history (4)：
- 2015/06 - 2020/03 Kyoto University Hakubi Center for Advanced Research Associate Professor
- 2009/10 - 2015/05 Boston Children's Hospital and Harvard Medical School
- 2009/10 - 2015/05 Harvard University, Wyss Institute for Biologically Inspired Engineering, Re
- 2006/04 - 2009/09 University of Michigan, Department of Biomedical Engineering, Postdoctoral Fellow
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