Toya Yoshihiro

トヤヨシヒロ | Toya Yoshihiro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://metabolic-engineering.jp/member/detail/1275

Research field (1)： Applied biofunctional and bioprocess engineering

Research keywords (6)：システム生物学 , 微生物 , 細胞シミュレーション , 代謝フラックス解析 , ゲノムスケール代謝モデル , 代謝工学

Research theme for competitive and other funds (12)：

2024 - 2029 A Study of Science and Process Construction of Microbial Gas-phase Reaction
2019 - 2024 High performance microbial cell factories development by model based metabolic design and adaptive laboratory evolution
2021 - 2024 微細藻類の変動光に対する光化学系と代謝のシステム解析
2018 - 2023 Synthesis of L- and D-homopoly-gamma-glutamic acids and elucidation of the mechanism
2019 - 2022 Identification of rate limiting step in metabolic pathway for bioproductions based on genome scale model

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Papers (69)：

Koichiro Ueno, Shogo Sawada, Mai Ishibashi, Yoshiki Kanda, Hiroshi Shimizu, Yoshihiro Toya. Identification of a novel NADPH generation reaction in the pentose phosphate pathway in Escherichia coli using mBFP. Journal of Bacteriology. 2024
Yujiro Hirose, Daniel C Zielinski, Saugat Poudel, Kevin Rychel, Jonathon L Baker, Yoshihiro Toya, Masaya Yamaguchi, Almut Heinken, Ines Thiele, Shigetada Kawabata, et al. A genome-scale metabolic model of a globally disseminated hyperinvasive M1 strain of Streptococcus pyogenes. mSystems. 2024. 9. 9. e0073624
Sefli Sri Wahyu Effendi, Yoshihiro Toya, Hiroshi Shimizu, Chengfeng Xue, I-Son Ng. Utilizing Ribose 1,5-Bisphosphate Isomerase and RuBisCO-Equipped <i>Escherichia coli</i> Nissle for Low-Carbon Footprint GABA Production. ACS Sustainable Chemistry & Engineering. 2024. 12. 30. 11093-11098
Hiroki Mori, Misato Matsui, Takahiro Bamba, Yoshimi Hori, Sayaka Kitamura, Yoshihiro Toya, Ryota Hidese, Hisashi Yasueda, Tomohisa Hasunuma, Hiroshi Shimizu, et al. Engineering Escherichia coli for efficient glutathione production. Metabolic Engineering. 2024
Yoshihiro Toya, Hiroshi Shimizu. Coupling and uncoupling growth and product formation for producing chemicals. Current Opinion in Biotechnology. 2024. 87. 103133

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MISC (186)：

小林祐摩, 佐野海瑚人, 弘埜陽子, 松田史生, 石井純, 原清敬, 清水浩, 戸谷吉博. Applications of a light-driven proton pump to enhance the weak acid tolerance and bioproduction in Escherichia coli. 日本生物工学会大会講演要旨集. 2023. 75th
二井手哲平, 杉木創, 森聖也, 戸谷吉博, 清水浩. Application of Logistic Regression Models for Identification of Residues Determining Substrate Specificity in Enzymes. 日本生物工学会大会講演要旨集. 2023. 75th
宮脇佳汰, 二井手哲平, 戸谷吉博, 清水浩. Thermal stability design of enzyme incorporated with evolutionary and structural information. 日本生物工学会大会講演要旨集. 2023. 75th
三吉健太, 一色衣香, 二井手哲平, 戸谷吉博, 清水浩. Metabolic pathway engineering for butyrolactam production in Escherichia coli harboring the non-oxidative glycolysis. 日本生物工学会大会講演要旨集. 2023. 75th
森聖也, 二井手哲平, 戸谷吉博, 清水浩. Estimation and transformation of substrate specificity determining residues of metabolic enzymes using machine learning. 日本生物工学会大会講演要旨集. 2023. 75th

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Patents (12)：

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Books (2)：

Lectures and oral presentations (20)：

Optogenetic technologies for microbial metabolic engineering
(Northeast Asian Symposium 2024 2024)
光を利用した新しい微生物バイオプロセスの開発(+α)
(関西バイオものづくりオンライン月例発表会 2024)
Microbial metabolic engineering using optogenetic tools
(Enzymes & Photosynthesis - key for a green and sustainable future - 2024)
光を利用して微生物の代謝の流れを制御するための技術開発
(JPC関西・ABPI研勉強会 2023)
微生物を利用した物質生産のための代謝経路設計とフラックス分布制御
(有用物質生産(7), JACI 2023)

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Education (3)：

Work history (5)：

2018/07 - 現在 Osaka University Graduate School of Information Science and Technology Associate Professor
2015/04 - 2018/07 Osaka University Graduate School of Information Science and Technology
2011/11 - 2015/04 Osaka University Graduate School of Information Science and Technology
2010/04 - 2011/10 慶応義塾大学大学院政策メディア研究科特任助教
2008/04 - 2010/03 日本学術振興会特別研究員 (DC2)

Committee career (5)：

Awards (7)：

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Association Membership(s) (3)：

JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , THE SOCIETY OF CHEMICAL ENGINEERS, JAPAN , The Society for Biotechnology, Japan

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