Kimura Tetsuya

Affiliation and department：

Research field (3)： Molecular biology , Immunology , Metabolism and endocrinology

Research keywords (5)：肥満症 , lipid metabolism , macrophage , Lamtor1 , Immunometabolism

Research theme for competitive and other funds (8)：

2022 - 2029 マクロファージは肥満症から世界を救う
2022 - 2024 Elucidating the role of metabolic signals integrated at lysosomes in osteoclasts
2018 - 2022 マクロファージは全身の脂質代謝を制御し、肥満症治療の標的となる
2019 - 2020 生体内の新たな脂質配分制御機構の解明と肥満症治療への応用
2020 - 世界から肥満症をなくす-脂質代謝に免疫細胞が及ぼすインパクト-

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Papers (26)：

Tetsuya Kimura, Yoshitomo Hayama, Daisuke Okuzaki, Shigeyuki Nada, Masato Okada. The Ragulator complex serves as a substrate-specific mTORC1 scaffold in regulating the nuclear translocation of transcription factor EB. The Journal of biological chemistry. 2022. 298. 3. 101744-101744
Takeshi Nakatani, Kohei Tsujimoto, JeongHoon Park, Tatsunori Jo, Tetsuya Kimura, Yoshitomo Hayama, Hachiro Konaka, Takayoshi Morita, Yasuhiro Kato, Masayuki Nishide, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nature communications. 2021. 12. 1. 3333-3333
Shizuka Ito, Shigeyuki Nada, Daisuke Yamazaki, Tetsuya Kimura, Kentaro Kajiwara, Hiroaki Miki, Masato Okada. p18/Lamtor1-mTORC1 Signaling Controls Development of Mucin-producing Goblet Cells in the Intestine. Cell structure and function. 2020. 45. 2. 93-105
Yohei Maeda, Takeshi Tsuda, Yoshito Takeda, Shohei Koyama, Yoshitomo Hayama, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Hyota Takamatsu, Sujin Kang, et al. SEMA4A promotes eosinophil survival and contributes to eosinophil-mediated allergic diseases. Allergology international : official journal of the Japanese Society of Allergology. 2019. 68. 2. 274-276
Tetsuya Kimura, Yoshitaka Hayashi, Yuka Tsukamoto, Yasuyuki Okamoto. The Mutant Thyroid Hormone Receptor Beta R320P Causes Syndrome of Resistance to Thyroid Hormone. Case Reports in Endocrinology. 2018. 2018. 4081769

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MISC (2)：

木庭太郎, 葉山善友, 木村哲也, 高松漂太, 熊ノ郷淳. カスパーゼ-1活性化を介したLamtor1のインフラマソーム及びパイロトーシスの制御. 生命科学系学会合同年次大会. 2017. 2017年度. [2P-0934]
木村哲也, 名田成之, 岡田雅人, 熊ノ郷淳. IL-4はLamtor1を足場としてmTORC1を活性化し、LXRを介してM2マクロファージを分化させる. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [2T特p-01(2P1150)]

Education (2)：

Professional career (1)：

Work history (9)：

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Awards (4)：

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