Art

J-GLOBAL ID：201902230307732575   Reference number：19A1369187

SEMA4A promotes eosinophil survival and contributes to eosinophil-mediated allergic diseases

SEMA4Aは好酸球生存を促進し,好酸球媒介アレルギー疾患の原因になる

Author (63)： Maeda Yohei (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Maeda Yohei (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Maeda Yohei (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Maeda Yohei (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Tsuda Takeshi (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Tsuda Takeshi (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Tsuda Takeshi (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Tsuda Takeshi (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Takeda Yoshito (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Koyama Shohei (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Koyama Shohei (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Koyama Shohei (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Hayama Yoshitomo (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Hayama Yoshitomo (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Hayama Yoshitomo (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Nojima Satoshi (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Nojima Satoshi (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Nojima Satoshi (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Nojima Satoshi (Department of Pathology, Osaka University Graduate School of Medicine) ,  Kimura Tetsuya (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Kimura Tetsuya (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Kimura Tetsuya (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Kimura Tetsuya (Department of Oncogene Research, Research Institute for Microbial Diseases, Osaka University) ,  Ito Daisuke (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Ito Daisuke (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Ito Daisuke (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Takamatsu Hyota (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Takamatsu Hyota (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Takamatsu Hyota (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Kang Sujin (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Kang Sujin (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Kang Sujin (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Kang Sujin (Department of Immune Regulation, Immunology Frontier Research Center, Osaka University) ,  Nishide Masayuki (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Nishide Masayuki (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Nishide Masayuki (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Morimoto Keiko (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Morimoto Keiko (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Morimoto Keiko (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Morimoto Keiko (Department of Anatomy, Keio University School of Medicine) ,  Hosokawa Takashi (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Hosokawa Takashi (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Hosokawa Takashi (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Kinehara Yuhei (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Kinehara Yuhei (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Kinehara Yuhei (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Kato Yasuhiro (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Kato Yasuhiro (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Kato Yasuhiro (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Nakatani Takeshi (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Nakatani Takeshi (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Nakatani Takeshi (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI)) ,  Takeda Kazuya (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Hayama Masaki (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Obata Sho (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Akazawa Hitoshi (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Akazawa Hitoshi (Department of Otolaryngology, Ikeda Municipal Hospital) ,  Shikina Takashi (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Shikina Takashi (Department of Otolaryngology, Ikeda Municipal Hospital) ,  Inohara Hidenori (Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine) ,  Kumanogoh Atsushi (Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine) ,  Kumanogoh Atsushi (Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center) ,  Kumanogoh Atsushi (Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI))
Material： Allergology International  (Allergol Int)
Volume： 68  Issue： 2  Page： 274-276(J-STAGE)  Publication year： 2019 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Sinusitis ,...
Semi thesaurus term： cellular signal transduction ,...

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JST classification (2)： Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Biological function  (EB03040U)

Reference (11)：

• 1. Kumanogoh A, Kikutani H. Immunological functions of the neuropilins and plexins as receptors for semaphorins. Nat Rev Immunol 2013;13:802-14.
• 2. Takamatsu H, Kumanogoh A. Diverse roles for semaphorin-plexin signaling in the immune system. Trends Immunol 2012;33:127-35.
• 3. Rosenberg HF, Dyer KD, Foster PS. Eosinophils: changing perspectives in health and disease. Nat Rev Immunol 2013;13:9-22.
• 4. Chaaban MR, Walsh EM, Woodworth BA. Epidemiology and differential diagnosis of nasal polyps. Am J Rhinol Allergy 2013;27:473-8.
• 5. Lambrecht BN, Hammad H. The immunology of asthma. Nat Immunol 2015;16:45-56.

Terms in the title (6)： Sema4A ,  好酸球 ,  生存 ,  促進 ,  アレルギー疾患 ,  原因