Research keywords (5)：
機械学習
, 立体構造
, アプタマー
, function
, Protein
Research theme for competitive and other funds (2)：
2021 - 2024 Development of a new design method for artificial nucleic acids
2018 - 2023 アプタマー情報をベースにした低分子医薬品創製プラットフォームの構築
Papers (38)：
Yulong Gou, Suyong Re, Kenji Mizuguchi, Chioko Nagao. Impact of Hydrogen Bonding on P-Glycoprotein Efflux Transport as Revealed by Evaluation of a De Novo Prediction Model. ACS Medicinal Chemistry Letters. 2023
Kyohei Koyama, Kosuke Hashimoto, Chioko Nagao, Kenji Mizuguchi. Attention network for predicting T-cell receptor-peptide binding can associate attention with interpretable protein structural properties. Frontiers in Bioinformatics. 2023. 3
Hitoshi Kawashima, Reiko Watanabe, Tsuyoshi Esaki, Masataka Kuroda, Chioko Nagao, Yayoi Natsume-Kitatani, Rikiya Ohashi, Hiroshi Komura, Kenji Mizuguchi. DruMAP: A Novel Drug Metabolism and Pharmacokinetics Analysis Platform. Journal of Medicinal Chemistry. 2023
Chioko Nagao, Mayumi Kamada, Masahiko Nakatsui, Akiko Fukagawa, Toshiaki Katayama, Shuichi Kawashima, Kenji Mizuguchi, Rika Abe. RDFization of Interview Forms for effective use of pharmaceutical documents. Japanese Journal of Drug Informatics. 2023. 24. 4. 187-195
Yayoi Natsume-Kitatani, Mari N Itoh, Yoshito Takeda, Masataka Kuroda, Haruhiko Hirata, Kohtaro Miyake, Takayuki Shiroyama, Yuya Shirai, Yoshimi Noda, Yuichi Adachi, et al. Data-driven patient stratification and drug target discovery by using medical information and serum proteome data of idiopathic pulmonary fibrosis patients. 2022
樋口千洋, 黒田正孝, 黒田正孝, 伊藤眞里, 長尾知生子, 長尾知生子, 浜本隆二, 黒橋禎夫, 高村大也, 奥野恭史, et al. Open platform “Mine′′: Development of Artificial Intelligence (AI) to accelerate new drug discovery. 医療情報学連合大会論文集(CD-ROM). 2022. 42nd
Tsuyoshi Esaki, Reiko Watanabe, Rikiya Ohashi, Yayoi Natsume-Kitatani, Hitoshi Kawashima, Chioko Nagao, Kenji Mizuguchi. Development of a pharmacokinetics prediction system using multiscale integrated modeling: 1. In silico prediction of fraction of unbound drug in the brain homogenate. 2018 International Meeting on 22nd MDO and 33rd JSSX. 2018
