Yoshida Tetsu

ヨシダテツ | Yoshida Tetsu

Affiliation and department：

Research field (3)： Neuroscience - general , Laboratory animal science , Genomics

Research keywords (3)： Neuroscience , Regenerating medicine , Genome editing

Research theme for competitive and other funds (7)：

2022 - 2025 Analyses of neuronal circuits using genetic MRI reporters
2020 - 2023 Generating a somatic marmoset HD model using HITI CRISPR genome editing approaches
2015 - 2018 Establishment of an efficient gene knock-in method using adnoviral vector and CRISPR
2012 - 2015 The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa
2011 - 2013 Gene correction and transplantation into pathology model marmoset of iPS cells from retinitis pimentosa patient

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Papers (20)：

Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, et al. Elavl3 is essential for the maintenance of Purkinje neuron axons. Sci Rep. 2018. 8. 1. 2722-2722
Shinichiro Okata, Shinsuke Yuasa, Tomoyuki Suzuki, Shogo Ito, Naomasa Makita, Tetsu Yoshida, Min Li, Junko Kurokawa, Tomohisa Seki, Toru Egashira, et al. Embryonic type Na+ channel beta-subunit, SCN3B masks the disease phenotype of Brugada syndrome. SCIENTIFIC REPORTS. 2016. 6. 34198
Tetsu Yoshida, Yoko Ozawa, Keiichiro Suzuki, Kenya Yuki, Manabu Ohyama, Wado Akamatsu, Yumi Matsuzaki, Shigeto Shimmura, Kohnosuke Mitani, Kazuo Tsubota, et al. The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa. MOLECULAR BRAIN. 2014. 7. 45
Kenya Yuki, Tetsu Yoshida, Seiji Miyake, Kazuo Tsubota, Yoko Ozawa. Neuroprotective role of superoxide dismutase 1 in retinal ganglion cells and inner nuclear layer cells against N-methyl-D-aspartate-induced cytotoxicity. EXPERIMENTAL EYE RESEARCH. 2013. 115. 230-238
Masateru Kataoka, Yuki Kawamuro, Nobuaki Shiraki, Rika Miki, Daisuke Sakano, Tetsu Yoshida, Takanori Yasukawa, Kazuhiko Kume, Shoen Kume. Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013. 430. 3. 1103-1108

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MISC (14)：

吉田哲, 岡野栄之. 脳神経研究における新たな「スーパーモデル」:マーモセット. 実験医学. 2018. 36. 12. 186-191
吉田哲. 遺伝子改変マーモセットを用いた精神・神経疾患研究への応用. 〜最新のゲノム編集/iPS細胞を含めた〜動物/疾患モデルの作成技術・病態解析・評価手法. 2017
坪田欣也, 小牧裕司, 高田則雄, 吉田哲, 田中謙二, 岡野栄之, 後藤浩, 坪田一男, 栗原俊英. fMRIを用いた光刺激によるC57BL6/jマウス視覚野活性化の同定. 日本眼科学会雑誌. 2016. 120. 臨増. 250-250
Kinya Tsubota, Yuji Komaki, Norio Takata, Tetsu Yoshida, Kenji F. Tanaka, Hideyuki Okano, Hiroshi Goto, Kazuo Tsubota, Toshihide Kurihara. Identification and Quantification of the Murine Visual Cortex Activity by Functional MRI. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2015. 56. 7
吉田哲, 小沢洋子, 鈴木啓一郎, 平林由香, 鈴木禎史, 小泉春菜, 結城賢弥, 小林哲郎, 大山学, 天谷雅行, et al. iPS細胞を用いた網膜色素変性症における視細胞の変性機構の解析. 再生医療. 2013. 12

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Patents (4)：

ES細胞の分化誘導方法
Musashi1によるNumb蛋白質発現抑制剤
ムサシ蛋白質2遺伝子欠損動物
膵臓幹細胞、肺絨毛細胞、肝幹細胞、又は膵臓癌の検出方法

Professional career (1)：

博士(医学) (大阪大学)

Work history (4)：

2020/04 - 現在 Keio University School of Medicine
2015/04 - 2020/03 理化学研究所脳神経科学研究センター
2013/04 - 2015/03 Saitama Medical University Research Center for Genomic Medicine
2009/03 - 2013/03 Keio University School of Medicine

Association Membership(s) (5)：

The Japanese Society for Genome Editing , Japan Sciety of Gene and Cell Therapy , THE JAPANESE SOCIETY OF INFLAMMATION AND REGENERATION , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS

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