Todaka Hiroshi

トダカヒロシ | Todaka Hiroshi

Affiliation and department：
Homepage URL (1)： http://www.kochi-ms.ac.jp/~ff_heart/

Research field (5)： Clinical pharmacy , Pathobiochemistry , Medical biochemistry , Physiology , Cell biology

Research keywords (7)：筋再生 , 筋線維タイプ , 筋萎縮 , サテライト細胞 , 心筋梗塞 , 虚血 , 非翻訳RNA

Research theme for competitive and other funds (7)：

2022 - 2025 認知症治療薬のドラッグリポジショニングによる筋ジストロフィーの新規治療法開発
2021 - 2024 Sigma 1受容体リガンドによる末梢動脈疾患に対する新規治療法の開発
2018 - 2020 Elucidation of the cell protective mechanism of acetylcholinesterase variants in cardiomyocyte and approach to therapy for myocardial infarction
2016 - 2019 Elucidation of molecular mechanisms through RNA-RNA binding protein network in physiological regulation and disease onset
2016 - 2019 Activation of cardioprotective cholinergic system by miRNA in ischemic heart disease

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Papers (13)：

Todaka Hiroshi, Arikawa Mikihiko, Noguchi Tatsuya, Ichikawa Atsushi, Higuchi Takuma, Sakamoto Shuji, Sato Takayuki. Promoting effect of sigma-1 receptor on the skeletal muscle differentiation and regeneration. The Journal of Physiological Sciences. 2024. 74. Suppl.2. 223-223
Hiroshi Todaka, Mikihiko Arikawa, Tatsuya Noguchi, Atsushi Ichikawa, Takayuki Sato. Donepezil, an anti-Alzheimer's disease drug, promotes differentiation and regeneration in injured skeletal muscle through the elevation of the expression of myogenic regulatory factors. European journal of pharmacology. 2021. 174528-174528
Ichikawa A, Yamasaki F, Ueda M, Todaka H, Miyao E, Yoshinaga Y, Yamanaka S, Matsumura Y, Sato T. Relationship between the fall in blood pressure in the standing position and diaphragmatic muscle thickness: proof of concept study. Blood pressure monitoring. 2019. 24. 6. 284-288
Nakane T, Ido A, Higuchi T, Todaka H, Morisawa K, Nagamine T, Fukunaga K, Sakamoto S, Murao K, Sugiyama Y. Candidate plasticity gene 16 mediates suppression of insulin gene expression in rat insulinoma INS-1 cells under glucotoxic conditions. Biochemical and biophysical research communications. 2019. 512. 2. 189-195
Higuchi T, Morisawa K, Todaka H, Lai S, Chi E, Matsukawa K, Sugiyama Y, Sakamoto S. A negative feedback loop between nuclear factor 90 (NF90) and an anti-oncogenic microRNA, miR-7. Biochemical and biophysical research communications. 2018. 503. 3. 1819-1824

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MISC (46)：

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Books (1)：

Lectures and oral presentations (1)：

Intervention in the mechanisms of muscle regeneration to prevent and treat skeletal muscle disorders
(The 44th Annual Meeting of the Japanese Society for Comparative Physiology and Biochemistry 2022)

Education (3)：

Professional career (1)：

Work history (3)：

Committee career (2)：

Awards (5)：

Association Membership(s) (5)：

THE JAPANESE BIOCHEMICAL SOCIETY , THE PHYSIOLOGICAL SOCIETY OF JAPAN , 日本筋学会 , 日本比較生理生化学会 , 日本病態生理学会

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