- 2024 - 2030 タウオパチーにおけるグリア-末梢免疫連関および脳プロテオスタシス変容の理解と制御
- 2023 - 2026 Next generation biomarker for Alzheimer's disease based on glial pathology
- 2024 - 2025 認知症治療標的としてのミクログリアによるアストロサイト制御機構に剖検脳から迫る
- 2022 - 2025 comprehensive search for expanded repeats in neurodegenerative diseaess
- 2022 - 2025 Loss of homeostatic microglia and cell replacement therapy in primary microgliopathy
- 2022 - 2025 認知症治療標的としてのミクログリアによるアストロサイト制御機構に剖検脳から迫る
- 2021 - 2024 タウオパチー病態機序解明を目指すゲノムリソースの網羅的機能解析
- 2021 - 2024 多系統萎縮症の3つの病態を反映し,早期診断を可能とするバイオマーカーの検討と確立
- 2020 - 2023 Bassoon proteinopathyの病態解析研究
- 2019 - 2022 Exploring rare variants associated with Alzheimer disease
- 2019 - 2022 Impaired essential function of microglia in the pathogenesis of HDLS/ALSP
- 2019 - 2022 Microglia-astrocyte crosstalk in leukoencephalopathies
- 2017 - 2019 Comprehensive search for biomarkers predicting dementia using urine metabolomics analysis
- 2016 - 2019 Microglial involvement in the pathomechanisms of white matter degeneration
- 2014 - 2019 Establishment of brain protein aging models; human iPS cell model and non-human primate model
- 2016 - 2018 CSF-1受容体異常によるミクログリア機能破綻と一次性ミクログリア病の病態
- 2015 - 2018 Validation study on insulin resistance occuring in brain of Alzheimer disease
- 2015 - 2018 Amino acid profile in plasma of Alzheimer's disease
- 2015 - 2017 Identification of the pathologically-transited immature cells diagnosed by soluble LR11
- 2014 - 2017 Amyotrophic Lateral Sclerosis and TDP-43: Elucidation of molecular neuropathology in terms of spread from its beginning
- 2014 - 2017 Analysis of the mechanism of homeostatic maintenance against Alzheimer's disease and its failure due to diabetes
- 2014 - 2017 Globular glial tauopathy: investigation of the pathological features
- 2014 - 2016 一次性ミクログリア病:CSF-1R変異関連HDLSにおけるミクログリアの機能異常
- 2012 - 2015 Identification of target molecules related the progression of Alzheimer's disease
- 2012 - 2014 末梢血におけるアルツハイマー病脳関連遺伝子のエピジェネティック・遺伝子発現解析
- 2011 - 2013 Genetical, morphological, and functional analysis of CHMP2B in a patient of familial FTD
- 2011 - 2013 Non-biased expression analysis to search for molecules associated with amyloid-beta induced hyperphosphorylation of tau
- 2009 - 2011 Mutations associated with copy number variation in neurological disorders
- 2010 - 2010 レビー小体型認知症の診断に有用な髄液中αシヌクレイン簡易ELISA測定キットの開発
- 2008 - 2010 A role of insulin signal impairment in the pathogenesis of Alzheimer disease
- 2007 - 2008 Global survey on clinical research supporting and promoting system, aiming Japanese clinical research improvement.
- 2006 - 2007 Modulation of β-amyloid and phosphorylated tau production by statin
- 2004 - 2005 A role of transcriptional impairment in pathogenesis for Alzheimer disease
- 2004 - 2004 特異的γセクレターゼ阻害剤を用いた活性型プレセニリン複合体の調節機構の解析
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