Rchr
J-GLOBAL ID:201801005891781121
Update date: Oct. 24, 2024
TAKAHIRO HIGUCHI
ヒグチ タカヒロ | TAKAHIRO HIGUCHI
Affiliation and department:
Research field (4):
Cardiology
, Tumor diagnostics and therapeutics
, Biomedical engineering
, Radiology
Research keywords (7):
Animal testing
, Nuclear medicine
, Heart failure
, immunology
, Cancer
, PET
, Molecular Imaging
Research theme for competitive and other funds (20):
- 2024 - 2027 ケモカイン受容体を標的としたラジオセラノスティクスプローブの開発
- 2024 - 2027 核医学レポーター蛋白の変異特性を利用した生体移植後細胞のモニタリング法の開発
- 2024 - 2026 Neutrophil-Specific PET Cellular Imaging for ARDS
- 2022 - 2026 Neutrophil-Specific PET Cellular Imaging for ARDS
- 2022 - 2025 医用画像生成ニューラルネットワークにおける共通特徴と固有特徴の独立学習手法の開発
- 2021 - 2024 New diagnostic and therapeutic strategy for organ fibrosis: Radionuclide ablation of active fibroblasts
- 2019 - 2023 トホグリフロジンの糖尿病性心筋症に及ぼす効果の検討
- 2019 - 2023 Zr-89標識イメージング技術に基づく次世代抗体医薬の創生プラットフォームの形成
- 2018 - 2021 Fundamental research on the effect of auditory bilateral stimulation on depressive symptoms
- 2018 - 2021 Asessment at plaque vulnerability quantification with magnetic reonance and molecular imagings
- 2017 - 2021 Development of ultra-high-resolution 3D fluorescent CT using x-ray tube for imaging molecular function and morphology simultaneously
- 2020 - 2021 高感度生体内トラッキング技術とiPS細胞技術を融合した前立腺がんに対する次世代型汎用性CAR-T細胞療法の開発
- 2017 - 2021 ヒト由来間葉系幹細胞を用いた、虚血心疾患、急性心筋炎モデル動物に対する有効性評価及び作用メカニズム等の基礎的研究
- 2018 - 2020 Challenges to the world's first simultaneous PET-SPECT-MRI imaging method
- 2019 - 2020 高感度生体内トラッキング技術とiPS細胞技術を融合した前立腺がんに対する次世代型汎用性CAR-T細胞療法の開発
- 2018 - 2020 糖尿病に起因する心筋拡張障害発症機序および運動による予防効果の解明
- 2018 - 2019 劇症型心筋炎に対するヒト間葉系幹細胞の有効性の探索研究
- 2017 - 2019 PETトレーサを用いたiPS細胞由来分化細胞の細胞機能
- 2016 - 2019 Construction of heart failure personalized medicine strategy by heart molecular imaging international collaborative research
- 2015 - 2018 Elucidation of blood flow control mechanisms for establishing a wide area of simulator of brain circulation after cerebral revascularization
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Papers (278):
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Kathrin Schorr, Xinyu Chen, Takanori Sasaki, Anahi Paula Arias-Loza, Johannes Lang, Takahiro Higuchi, Achim Goepferich. Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles. ACS pharmacology & translational science. 2024. 7. 9. 2604-2611
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Rudolf A Werner, Yingjun Zhi, Niklas Dreher, Samuel Samnick, Aleksander Kosmala, Takahiro Higuchi, Lena Bundschuh, Constantin Lapa, Andreas K Buck, Max S Topp, et al. Interobserver Agreement Rates on CXCR4-Directed PET/CT in Patients with Marginal Zone Lymphoma. Molecular imaging and biology. 2024
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Philipp E Hartrampf, Sebastian E Serfling, Takahiro Higuchi, Jörg Bojunga, Alexander Weich, Rudolf A Werner. [Clinical significance of neuroendocrine tumors : Incidence, symptoms, diagnosis, stage, and prognostic factors and their influence on disease management]. Radiologie (Heidelberg, Germany). 2024. 64. 7. 536-545
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Jorge D Oldan, Martin G Pomper, Rudolf A Werner, Takahiro Higuchi, Steven P Rowe. The cutting edge: Promising oncology radiotracers in clinical development. Diagnostic and interventional imaging. 2024
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Susanne Knorr, Lisa Rauschenberger, Muthuraman Muthuraman, Rhonda McFleder, Thomas Ott, Kathrin Grundmann-Hauser, Takahiro Higuchi, Jens Volkmann, Chi Wang Ip. Disturbed brain energy metabolism in a rodent model of DYT-TOR1A dystonia. Neurobiology of disease. 2024. 194. 106462-106462
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MISC (140):
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屋木祐亮, 屋木祐亮, 屋木祐亮, 木村寛之, 樋口隆弘, 樋口隆弘. Optimization Study of F-18 Indirect Labeling Reagents Boronic Acid Derivatives 3-[18F]TDBFB and 4-[18F]TDBFB. 日本薬学会年会要旨集(Web). 2024. 144th
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屋木祐亮, 屋木祐亮, 屋木祐亮, 屋木祐亮, 木村寛之, 樋口隆弘, 樋口隆弘, 樋口隆弘. Synthesis of boronic acid derivatives TDBFB for F-18 indirect labeling using Suzuki coupling. 日本薬学会年会要旨集(Web). 2023. 143rd
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屋木祐亮, 屋木祐亮, 屋木祐亮, 近藤悠斗, 樋口隆弘, 木村寛之. Development of the novel F-18 labeling method using Suzuki coupling reaction with F-18 labeled boronic acid derivatives. 日本薬学会年会要旨集(Web). 2022. 142nd
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樋口 隆弘. 心臓分子イメージングにおけるパラダイムシフト 新規F18標識PET放射性トレーサーを利用したオーダーメイド医療(Paradigm Shifts in Molecular Cardiac Imaging: Precision Medicine through Novel F18-labeled PET Radiotracers). 日本循環器学会学術集会抄録集. 2021. 85回. ME02-1
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近藤悠斗, 木村寛之, 屋木祐亮, 屋木祐亮, 樋口隆弘, 樋口隆弘, 安井裕之. Cu-Mediated Radio-Iodination from Boronic Acid and Ester. 日本薬学会年会要旨集(Web). 2021. 141st
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Patents (5):
Education (2):
- 1998 - 2002 Kanazawa University Graduate School of Medical Science
- 1992 - 1998 University of Toyama Faculty of Medicine School of Medicine
Professional career (1):
Work history (6):
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