Nakamura Jun

Affiliation and department：

Research field (1)： Veterinary medicine

Research keywords (22)： DAMPS , 内因性抗体 , 内因性抗原 , 酸化特異的エピトープ , 内因性DNA障害 , クロスリンク , 1,4-dihydropyridine , M2AA , M2FA , 自然免疫 , 内因性アルデヒド , ファンコニ貧血 , ADH5 , ALDH2 , アセトアルデヒド , ホルムアルデヒド , 電子たばこ , 遺伝子変異 , DNA損傷と修復 , 発癌機序 , 酸化ストレス , 生活習慣病

Research theme for competitive and other funds (4)：

2021 - 2024 内因性ホルムアルデヒドの蓄積に起因する疾病
2020 - 2023 Formaldehyde induces superbulky DNA interstrand crosslinks
2018 - 2021 加熱式たばこなど新たなたばこ製品の成分分析と受動喫煙による健康影響の評価手法の開発
2017 - 2019 Immune response to lysine adducts in atherogenesis

Papers (101)：

Jun Nakamura, Sujey Carro, Avram Gold, Zhenfa Zhang. An unexpected butadiene diolepoxide-mediated genotoxicity implies alternative mechanism for 1,3-butadiene carcinogenicity. Chemosphere. 2021. 266. 129149-129149
Jun Nakamura. Potential doxorubicin-mediated dual-targeting chemotherapy in FANC/BRCA-deficient tumors via modulation of cellular formaldehyde concentration. Chemical Research in Toxicology. 2020. 33. 10. 2659-2667
Shaomin Tian, Jun Nakamura, Sylvia Hiller, Stephen Simington, Darcy W. Holley, Roberto Mota, Monte S. Willis, Scott J. Bultman, J. Christopher Luft, Joseph M. DeSimone, et al. New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis. Vascular Pharmacology. 2020. 133-134. 106777-106777
Jun Nakamura, Darcy W. Holley, Toshihiro Kawamoto, Scott J. Bultman. The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice. Genes and Environment. 2020. 42. 21
Yi, Xianwen, Wang, Ying, Jia, Zhenquan, Hiller, Sylvia, Nakamura, Jun, Luft, J. Christopher, Tian, Shaomin, DeSimone, Joseph M. Retinoic Acid-Loaded Poly(lactic-co-glycolic acid) Nanoparticle Formulation of ApoB-100-Derived Peptide 210 Attenuates Atherosclerosis. Journal of Biomedical Nanotechnology. 2020. 16. 4. 467-480

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MISC (24)：

中村純. ホルムアルデヒド/アセトアルデヒドにより産生される蛍光性付加体と免疫反応. 日本分子生物学会年会、フォーラム、環境因子と生体防御機構をイメージする!. 2020
中村純, Sujey Carro, Avram Gold, Zhenfa Zhang. エポキシブタンジオールの遺伝毒性の解析により明らかになったブタジエンの新たな発癌メカニズム. 日本環境変異原学会、年次大会. 2020. O4-1
Jun Nakamura, Sujey Carro, Avram, Zhenfa Zhang. Unexpected 3-Butene-1,2-Diol-Mediated Genotoxicity Implies Alternative Mechanism of 1,3-Butadiene Carcinogenesis. 2020
Jun Nakamura, Masanobu Kawanishi, Takashi Yagi, Toshiya Okada, Naoki Kunugita. Antigenic, Inflammatory DHP-Lysine Adducts Are Induced by Aldehydes in the Vapor of Both Flavored and Unflavored E-cigarettes and Heated Tobacco Products. Society of Toxicology Annual Meeting 2020. 2020
中村純. 内因性アルデヒド:DNAメタボリズムからメタボリックシンドロームまで. 日本環境変異原学会、変異機構研究会、夏の学校. 2019

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Education (3)：

1995 - 1999 University of North Carolina at Chapel Hill School of Public Health Department of Environmental Sciences and Engineering
1982 - 1984 大阪府立大学農学研究科獣医学博士前期課程
1978 - 1982 大阪府立大学農学部獣医学

Work history (6)：

2022/04 - 現在 Osaka Metroploitan University School of Veterinary Science Visiting Scientist
2017/04 - 2022/03 Osaka Prefecture University
2009/06 - 2017/01 ノースキャロライナ大学チャペルヒル校公衆衛生学部環境科学工学科 Research Associate Professor
2000/06 - 2009/05 ノースキャロライナ大学チャペルヒル校公衆衛生学部環境科学工学科 Research Assistant Professor
2000/01 - 2000/05 ノースキャロライナ大学チャペルヒル校公衆衛生学部環境科学工学科 Research Associate

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Awards (6)：

2003 - The University of North Carolina at Chapel Hill Edward Kidder Graham Teaching Award
2000 - Aspen Cancer Conference Young Investigator Travel Award
2000 - School of Public Health-University of North Carolina at Chapel Hill Bernard G. Greenberg Best Dissertation Award
1999 - Lineberger Comprehensive Cancer Center-University of North Carolina at Chapel Hill Dissertation Award for the Population Sciences
1998 - American Association for Cancer Research Travel Award

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Association Membership(s) (2)：

Sigma Xi - Full Member, Scientific Research Honor Society , 日本環境変異原学会

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