Hara Yuichiro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://sites.google.com/view/yuichirohara/home

Research field (4)： Evolutionary biology , Genomics , Systems genomics , Medical biochemistry

Research keywords (6)：マルチオミクス , シスエレメント , ゲノム解読 , 次世代シーケンサー , Comparative genomics , Molecular evolution

Research theme for competitive and other funds (3)：

2021 - 2024 Elucidation of de novo gene birth and pseudogenization processes via reconstruction of ancestral transcriptional regulation
2019 - 2023 慢性炎症性疾患の免疫細胞における脂質リプログラミングの意義の解明
2012 - 2014 Evolutionary genomics of ultramicro inversions.

Papers (36)：

Okiru Komine, Syuhei Ohnuma, Kunihiko Hinohara, Yuichiro Hara, Mayuko Shimada, Tomohiro Akashi, Seiji Watanabe, Akira Sobue, Noe Kawade, Tomoo Ogi, et al. Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice. iScience. 2024. 27. 2. 108872-108872
Akari Nakamura, Seiichiro Sakai, Yoshitaka Taketomi, Jun Tsuyama, Yoshimi Miki, Yuichiro Hara, Nobutaka Arai, Yuki Sugiura, Hideya Kawaji, Makoto Murakami, et al. PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke. Neuron. 2023. 111. 19. 2995-3010.e9
Yuichiro Hara, Shigehiro Kuraku. The impact of local genomic properties on the evolutionary fate of genes. eLife. 2023. 12
Yuichiro Hara, Takuma Kumamoto, Naoko Yoshizawa-Sugata, Kumiko Hirai, Song Xianghe, Hideya Kawaji, Chiaki Ohtaka-Maruyama. Spatial transcriptome of developmental mouse brain reveals temporal dynamics of gene expressions and heterogeneity of the claustrum. 2023
David M Linz, Yuichiro Hara, Kevin D Deem, Shigehiro Kuraku, Shigeo Hayashi, Yoshinori Tomoyasu. Transcriptomic exploration of the Coleopteran wings reveals insight into the evolution of novel structures associated with the beetle elytron. Journal of experimental zoology. Part B, Molecular and developmental evolution. 2023. 340. 2. 197-213

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MISC (3)：

Professional career (1)：

Work history (10)：

2024/04 - 現在 Kitasato University School of Frontier Engineering Associate Professor
2024/04 - 現在 Tokyo Metropolitan Institute of Medical Science
2023/04 - 2024/03 Kitasato University
2020/07 - 2024/03 Tokyo Metropolitan Institute of Medical Science Research Center for Genome & Medical Sciences Chief Researcher
2018/10 - 2022/03 理化学研究所生命機能科学研究センター客員研究員

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Association Membership(s) (5)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , SOCIETY OF EVOLUTIONARY STUDIES, JAPAN , Society for Molecular Biology and Evolution , 日本人類遺伝学会 , 日本遺伝学会

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