KAWAGISHI Hiroyuki

Affiliation and department：

Research keywords (5)：肝毒性 , 安全性薬理 , Cellular Senescence , Cardiomyocytes , Pediatric heart failure

Papers (16)：

Hideki Kobayashi, Shugo Tohyama, Hajime Ichimura, Noburo Ohashi, Shuji Chino, Yusuke Soma, Hidenori Tani, Yuki Tanaka, Xiao Yang, Naoko Shiba, et al. Regeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell-Derived Cardiac Spheroids. Circulation. 2024
Hiroyuki Kawagishi, Tsutomu Nakada, Takuro Numaga-Tomita, Maite Larrañaga, Ang Guo, Long-Sheng Song, Mitsuhiko Yamada. Cytokine receptor gp130 promotes postnatal proliferation of cardiomyocytes required for the normal functional development of the heart. American Journal of Physiology-Heart and Circulatory Physiology. 2022
Nanqi Cui, Takayuki Sakurai, Akiko Kamiyoshi, Yuka Ichikawa-Shindo, Hisaka Kawate, Megumu Tanaka, Masaaki Tanaka, Yangxuan Wei, Shinji Kakihara, Yunlu Zhao, et al. Adrenomedullin-RAMP2 and -RAMP3 Systems Regulate Cardiac Homeostasis during Cardiovascular Stress. Endocrinology. 2021. 162. 3
Ryan Houston, Shiori Sekine, Michael J Calderon, Fayaz Seifuddin, Guanghui Wang, Hiroyuki Kawagishi, Daniela A Malide, Yuesheng Li, Marjan Gucek, Mehdi Pirooznia, et al. Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses. PLoS biology. 2020. 18. 11. e3000981
Toshihide Kashihara, Hiroyuki Kawagishi, Tsutomu Nakada, Takuro Numaga-Tomita, Shin Kadota, Elena E Wolf, Cheng-Kun Du, Yuji Shiba, Sachio Morimoto, Mitsuhiko Yamada. β-Arrestin-Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate. JACC. Basic to translational science. 2020. 5. 11. 1057-1069

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MISC (9)：

諫田泰成, 川岸裕幸. New trend on safety pharmacology. Pharm Tech Japan. 2024. 40. 9
Hiroyuki Kawagishi, Shota Yanagida, Yasunari Kanda. Drug Development Using Human iPSC-Derived Cardiomyocytes and Future Perspectives. Reference Module in Biomedical Sciences. 2024
柳田翔太, 川岸裕幸, 諫田泰成. 抗がん薬の心毒性リスク評価と今後の展望. 日本薬理学会雑誌. 2023
川岸裕幸, 山田充彦. βアレスチンバイアス性アンジオテンシンII 1型受容体アゴニストによる新たな小児心不全治療戦略の創生. 血管. 2022
川岸裕幸, 山田充彦. 新生児マウス心臓の機能的発達におけるサイトカイン受容体gp130の役割. 信州医学雑誌. 2022

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Books (2)：

腫瘍循環器学 -新しい学際領域の最新知見-
日本臨牀 2024
老年医学(上巻)-基礎・臨床研究の最新動向-
日本臨牀 2018

Lectures and oral presentations (30)：

Drug Development for Pediatric Heart Failure: Neonatal-Specific Functions of Cardiac Angiotensin Receptor
(2024 Fall International Convention of The Pharmaceutical Society of Korea 2024)
AT1アンジオテンシン受容体の生理作用を利用した新規乳幼児心不全治療薬の開発
(第144回日本薬理学会関東部会 2021)
A novel way of modification of AT1 angiotensin receptors to alleviate pediatric heart failure
(2021)
Postnatal loss of gp130 caused impaired cardiac contractility accompanied by inhibition of physiological proliferation of cardiomyocytes
(心血管国際研究集会2020 2020)
アンジオテンシンII 1型受容体ーβアレスチン経路を活性化する小児心不全治療薬の開発
(第30回日本循環薬理学会 2020)

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Professional career (1)：

Ph.D. (Nagoya University, School of Medicine)

Awards (5)：

2022/12 - 第96回日本薬理学会年会 Young Investigator Award
2022/06 - 第146回日本薬理学会関東部会優秀発表賞
2021/07 - 第50回日本心脈管作動物質学会研究奨励賞最優秀賞
2020/11 - 第30回日本循環薬理学会 Young Investigator Award
2008 - National Center for Geriatrics and Gerontology Young Investigator Award

Association Membership(s) (12)：

肝細胞研究会 , 日本毒性学会 , 日本薬学会 , SPS , 日本安全性薬理学会 , 日本生理学会 , 日本基礎老化学会 , THE JAPANESE PHARMACOLOGICAL SOCIETY , 日本心脈管作動物質学会 , Japanese Association of Cardiovascular Pharmacology , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , International Society for Heart Research

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