Rchr
J-GLOBAL ID：201801006589906078
Update date: Apr. 19, 2024
Mano Yasunobu
マノ ヤスノブ | Mano Yasunobu
Affiliation and department：
Research field (3)：
Molecular biology
, Genetics
, Genomics
Research keywords (5)：
DDS
, 癌免疫
, エピジェネティクス
, 細胞老化
, 癌
Research theme for competitive and other funds (4)：
- 2019 - 2021 Crosstalk between activated Notch and inactivated TGF-beta signaling in cancer cells
- 2018 - 2021 JAG1-Notchシグナル活性化による早期細胞老化と微小環境機構の解明
- 2017 - 2019 Analysis of Ras/Raf-induced senescence by activated JAG1-Notch signaling
- 2010 - 2012 エピジェネティックな遺伝子発現調節機構の切り替わりを制御する原因遺伝子の解明
Papers (16)：
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Feifei Wei, Taku Kouro, Yuko Nakamura, Hiroki Ueda, Susumu Iiizumi, Kyoko Hasegawa, Yuki Asahina, Takeshi Kishida, Soichiro Morinaga, Hidetomo Himuro, et al. Enhancing Mass spectrometry-based tumor immunopeptide identification: machine learning filter leveraging HLA binding affinity, aliphatic index and retention time deviation. Computational and structural biotechnology journal. 2024. 23. 859-869
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Taku Kouro, Naoko Higashijima, Shun Horaguchi, Yasunobu Mano, Rika Kasajima, Huihui Xiang, Yuki Fujimoto, Hiroyuki Kishi, Hiroshi Hamana, Daisuke Hoshino, et al. Novel chimeric antigen receptor-expressing T cells targeting the malignant mesothelioma-specific antigen sialylated HEG1. International journal of cancer. 2024. 154. 10. 1828-1841
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Hidetomo Himuro, Yoshiro Nakahara, Yuka Igarashi, Taku Kouro, Naoko Higashijima, Norikazu Matsuo, Shuji Murakami, Feifei Wei, Shun Horaguchi, Kayoko Tsuji, et al. Clinical roles of soluble PD-1 and PD-L1 in plasma of NSCLC patients treated with immune checkpoint inhibitors. Cancer immunology, immunotherapy : CII. 2023. 72. 8. 2829-2840
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Yoshiro Nakahara, Taku Kouro, Satoru Motoyama, Masatomo Miura, Kazuma Fujita, Yuka Igarashi, Naoko Higashijima, Norikazu Matsuo, Hidetomo Himuro, Feifei Wei, et al. Circulating IL-6 and not its circulating signaling components sIL-6R and sgp130 demonstrate clinical significance in NSCLC patients treated with immune checkpoint inhibitors. Frontiers in cell and developmental biology. 2023. 11. 1324898-1324898
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Takato Inoue, Kazuaki Matsuda, Keisuke Matsusaka, Masaya Nakajima, Yukari Takeno, Toko Miyazaki, Takahiko Shintaku, Natsumi Yoda, Takahiko Saito, Eriko Ikeda, et al. Anti-proliferating and apoptosis-inducing activity of chemical compound FTI-6D in association with p53 in human cancer cell lines. Chemico-Biological Interactions. 2022. 110257-110257
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MISC (48)：
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中原善朗, 洞口俊, 洞口俊, 東公一, 紅露拓, 紅露拓, 氷室秀知, 氷室秀知, 魏菲菲, 魏菲菲, et al. ICI治療における血漿中Neutrophil extracellular trapsの効果予測因子としての意義. 日本肺癌学会学術集会号. 2023. 64th (CD-ROM)
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辻嘉代子, 中村有子, 紅露拓, 魏菲菲, 眞野恭伸, 洞口俊, 洞口俊, 氷室秀知, 星野大輔, 川村猛, et al. 腎がん患者由来オルガノイドの樹立と免疫学的解析の試み. 日本がん免疫学会総会プログラム・抄録集. 2023. 27th
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洞口俊, 洞口俊, 中原善朗, 紅露拓, 氷室秀知, 魏菲菲, 眞野恭伸, 辻嘉代子, 神谷郁也, 東公一, et al. 抗PD-1/PD-L1抗体で治療された非小細胞肺癌患者における血漿中Neutrophil extracellular trapsの臨床的意義. 日本がん免疫学会総会プログラム・抄録集. 2023. 27th
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氷室秀知, 氷室秀知, 中原善朗, 中原善朗, 五十嵐友香, 紅露拓, 紅露拓, 村上修司, 魏菲菲, 魏菲菲, et al. 免疫チェックポイント阻害剤で治療された非小細胞肺がん患者における血漿中可溶性PD-1およびPD-L1の臨床的意義. 日本がん免疫学会総会プログラム・抄録集. 2023. 27th
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紅露拓, 眞野恭伸, 笠島理加, 辻祥太郎, 今井浩三, 笹田哲朗. 中皮腫特異的自己活性化CAR-T細胞のシグナル解析. 日本がん免疫学会総会プログラム・抄録集. 2023. 27th
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Patents (2)：
Professional career (1)：
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