Research theme for competitive and other funds (14):
2022 - 2025 Elucidation of mechanisms of carcinogenesis, metastasis, and metabolism based on histological characteristics of HNF4alpha-positive lung adenocarcinoma
2020 - 2024 Development of novel diagnostic and therapeutic approaches to cancer by analyzing specific features of the immunoglobulin superfamily of molecules.
2022 - 2024 Comprehensive identification of the ligand-receptor interactions regulating immune checkpoints
2021 - 2024 細胞接着分子CADM1による小細胞肺がんの増殖、転移促進機構の解明
2020 - 2022 Development of novel intervening approaches to cancer progression by comprehensive analyses of interactions between cell adhesion molecules
2020 - 2022 胆道がんへの治療応用を目指した新規免疫チェックポイント分子の探索
2020 - 2022 Mathematical analysis of cancer metastasis focused on cancer cell-endothelial cell interactions
2019 - 2021 Identification of trans-interacting receptors for CADM1
Yue Guo, Yutaka Kasai, Yuto Tanaka, Yuki Ohashi-Kumagai, Takeharu Sakamoto, Takeshi Ito, Yoshinori Murakami. IGSF3 is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium. Cancer science. 2024
Ryota Matsuoka, Hitomi Kawai, Takeshi Ito, Daisuke Matsubara. Determining Whether YAP1 and POU2F3 Are Antineuroendocrine Factors. Journal of Thoracic Oncology. 2022. 17. 9. 1070-1073
Hitomi Kawai, Ryouta Matsuoka, Takeshi Ito, Daisuke Matsubara. Molecular Subtypes of High-Grade Neuroendocrine Carcinoma (HGNEC): What is YAP1-Positive HGNEC?. Frontiers in bioscience (Landmark edition). 2022. 27. 3. 108-108
Yutaka Kasai, Siew Pey Gan, Toko Funaki, Yuki Ohashi-Kumagai, Mizuki Tominaga, Shu-Jen Shiu, Daisuke Suzuki, Daisuke Matsubara, Takeharu Sakamoto, Mika Sakurai-Yageta, et al. Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium. Cancer science. 2022. 113. 5. 1669-1678
Ken Akashi, Toshihiko Sakai, Osamu Fukuoka, Yuki Saito, Masafumi Yoshida, Mizuo Ando, Takeshi Ito, Yoshinori Murakami, Tatsuya Yamasoba. Usefulness of circulating tumor DNA by targeting human papilloma virus-derived sequences as a biomarker in p16-positive oropharyngeal cancer. Scientific reports. 2022. 12. 1. 572-572