Rchr
J-GLOBAL ID：201801007491910561   Update date: Oct. 20, 2024

Osawa Tsuyoshi

Osawa Tsuyoshi | Osawa Tsuyoshi
Affiliation and department：
The University of Tokyo Research Center for Advanced Science and Technology

About The University of Tokyo Research Center for Advanced Science and Technology


Homepage URL  (1)： https://www.onc.rcast.u-tokyo.ac.jp/ja/
Research field  (1)： Tumor biology
Research keywords  (1)： 分子腫瘍学
Research theme for competitive and other funds  (16)：
  • 2022 - 2025 横紋筋肉腫メタボローム解析(尿/組織)による診断マーカーとオンコメタボライト探索
  • 2022 - 2025 腎芽腫メタボローム解析(尿/組織)による診断マーカーとオンコメタボライト探索
  • 2021 - 2024 腎芽腫患児の代謝物網羅解析によるバイオマーカーの探索と創薬への挑戦
  • 2021 - 2023 Elucidation of metabolointeractome in tumor microenvironments
  • 2019 - 2023 Tolerance of cancer cells against amino acids deprivation in tumor microenvironments
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Papers (44)：
  • Manami Katoh, Seitaro Nomura, Shintaro Yamada, Masamichi Ito, Hiroki Hayashi, Mikako Katagiri, Tuolisi Heryed, Takayuki Fujiwara, Norifumi Takeda, Miyuki Nishida, et al. Vaccine Therapy for Heart Failure Targeting the Inflammatory Cytokine Igfbp7. Circulation. 2024
  • Juri Sakata, Toshifumi Tatsumi, Akira Sugiyama, Akihiro Shimizu, Yuya Inagaki, Hiroto Katoh, Takefumi Yamashita, Kazuki Takahashi, Sho Aki, Yudai Kaneko, et al. Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin. Protein expression and purification. 2023. 106375-106375
  • Ryuichi Nakahara, Sho Aki, Maki Sugaya, Haruka Hirose, Miki Kato, Keisuke Maeda, Daichi M Sakamoto, Yasuhiro Kojima, Miyuki Nishida, Ritsuko Ando, et al. Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth. The EMBO journal. 2023. e114032
  • Miki Kato, Keisuke Maeda, Ryuichi Nakahara, Haruka Hirose, Ayano Kondo, Sho Aki, Maki Sugaya, Sana Hibino, Miyuki Nishida, Manami Hasegawa, et al. Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils. PNAS nexus. 2023. 2. 10. pgad306
  • Sana Hibino, Shotaro Eto, Sho Hangai, Keiko Endo, Sanae Ashitani, Maki Sugaya, Tsuyoshi Osawa, Tomoyoshi Soga, Tadatsugu Taniguchi, Hideyuki Yanai. Tumor cell-derived spermidine is an oncometabolite that suppresses TCR clustering for intratumoral CD8+ T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 24. e2305245120
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MISC (37)：
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Education (3)：
  • 2001 - 2005 英国ロンドン大学 医学部大学院博士課程 腫瘍学専攻
  • 1998 - 2001 英国ロンドン大学 キングスカレッジ 医療生化学部
  • 1997 - 1998 英国ロンドン大学 医学系準備コース
Professional career (1)：
  • 博士(腫瘍学) (ロンドン大学)
Work history (6)：
  • 2023/04 - 現在 The University of Tokyo Division of Nutriomics and Oncology, RCAST Associate Professor
  • 2018/03 - 2023/03 The University of Tokyo Research Center for Advanced Science and Technology
  • 2011/04 - 2018/02 The University of Tokyo Research Center for Advanced Science and Technology
  • 2007/04 - 2011/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
  • 2007/04 - 2007/12 The University of Tokyo The Institute of Medical Science
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Awards (11)：
  • 2018/03 - 第4回血管生物医学会若手研究会 血管生物医学若手最優秀賞
  • 2018/01 - 平成29年先端モデル動物支援プラットフォーム成果発表会 優秀口演賞
  • 2016/11 - 第2回AMEDがん若手研究者ワークショップ BestReferee
  • 2016/11 - 第2回AMEDがん若手研究者ワークショップ BestPoster
  • 2016/09 - 平成28年疾患モデル動物支援プラットフォーム若手支援技術講習会 ベストトーク賞
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Association Membership(s) (3)：
The Molecular Biology Society of Japan ,  The Japanese Vascular Biology and Medicine Organization ,  Japanese Cancer Association
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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