Hirahashi Junichi

淳一平橋 | Hirahashi Junichi

Affiliation and department：

Research field (1)： Immunology

Research keywords (7)： rhabdomyolysis , neutrophil extracellular traps , ANCA , vasculitis , macrophage , neutrophil , nephritis

Research theme for competitive and other funds (7)：

2022 - 2026 白血球細胞外トラップを標的としたクラッシュシンドローム新規治療薬の開発
2021 - 2024 スフィンゴリン脂質によるFc受容体のリガンド親和性調節機構の解明
2018 - 2022 Elucidation of inflammatory mechanism and development of new treatment by immunological analysis of platelet-leukocyte contact
2015 - 2018 Investigation of Dysregulated Immunothrombosis in inflammatory diseases and development of a new therapeutic tool.
2012 - 2015 Regulation of neutrophil extracellular traps via fenton reaction and its application to the treatment of refractory autoimmune vasculitis

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Papers (94)：

Joanna C. Robson, Peter C. Grayson, Cristina Ponte, Ravi Suppiah, Anthea Craven, Andrew Judge, Sara Khalid, Andrew Hutchings, Richard A. Watts, Peter A. Merkel, et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Granulomatosis With Polyangiitis. Arthritis and Rheumatology. 2022. 74. 3. 393-399
Peter C. Grayson, Cristina Ponte, Ravi Suppiah, Joanna C. Robson, Anthea Craven, Andrew Judge, Sara Khalid, Andrew Hutchings, Raashid A. Luqmani, Richard A. Watts, et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic Granulomatosis With Polyangiitis. Arthritis and Rheumatology. 2022. 74. 3. 386-392
Ravi Suppiah, Joanna C. Robson, Peter C. Grayson, Cristina Ponte, Anthea Craven, Sara Khalid, Andrew Judge, Andrew Hutchings, Peter A. Merkel, Raashid A. Luqmani, et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Microscopic Polyangiitis. Arthritis and Rheumatology. 2022. 74. 3. 400-406
Osamu Yamazaki, Maho Yamashita, Jinping Li, Fumika Ochiai-Homma, Tadashi Yoshida, Junichi Hirahashi, Taiji Furukawa, Ken Kozuma, Yoshihide Fujigaki, George Seki, et al. A novel I551F variant of the Na+/HCO3- cotransporter NBCe1-A shows reduced cell surface expression, resulting in diminished transport activity. American journal of physiology. Renal physiology. 2021. 321. 6. F771-F784
Sara Monti, Anthea Craven, Catherine Klersy, Carlomaurizio Montecucco, Roberto Caporali, Richard Watts, Peter A Merkel, Raashid Luqmani, Katerina Achilleos, Matthew Adler, et al. Association between age at disease onset of anti-neutrophil cytoplasmic antibody-associated vasculitis and clinical presentation and short-term outcomes. Rheumatology. 2021. 60. 2. 617-628

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MISC (23)：

山崎修, 山下真帆, 李金萍, 本間文佳, 吉田理, 平橋淳一, 内田俊也, 林松彦, 柴田茂. ナトリウム重炭酸共輸送体NBCe1の膜貫通部位SNP機能解析. 日本腎臓学会誌. 2020. 62. 4. 297-297
Aika Hagiwara, Junichi Hirahashi, Hirobumi Tokuyama, Matsuhiko Hayashi, Shu Wakino, Hiroshi Itoh. THE EXAMINATION OF THE PROGNOSTIC FACTORS OF CALCIPHYLAXIS. RHEUMATOLOGY. 2017. 56. 162-162
Miho Kurosawa, Koshu Okubo, Osamu Yamazaki, Matsuhiko Hayashi, Junichi Hirahashi. HISTONE REQUIRES MAC-1 (CD11B/CD18)-MEDIATED NEUTROPHIL-PLATELET INTERACTION TO INDUCE THROMBOEMBOLISM. RHEUMATOLOGY. 2017. 56. 114-114
Koshu Okubo, Miho Kurosawa, Matsuhiko Hayashi, Junichi Hirahashi. MACROPHAGE EXTRACELLULAR TRAPS INDUCED BY MAC-1 (CD11B/CD18) DEPENDENT PLATELET-MACROPHAGE INTERACTIONS PROGRESS ACUTE KIDNEY INJURY. RHEUMATOLOGY. 2017. 56. 113-114
J. Hirahashi, K. Okubo, T. Mayadas, Y. Urano, M. Hayashi. MAC-1 (CD11B/CD18)-MEDIATED MACROPHAGE EXTRACELLULAR TRAPS PRODUCTION IS CRITICAL TO RHABDOMYOLYSIS-INDUCED ACUTE KIDNEY INJURY. NEPHROLOGY. 2016. 21. 140-141

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Lectures and oral presentations (58)：

横紋筋融解症に続発する急性腎障害の新たな展開:マクロファージ細胞外トラップ
(日本筋学会学術集会プログラム・抄録集 2018)
ヒストンによる血小板凝集の形態的解析
(日本血栓止血学会誌 2018)
次世代シークエンサーにより,遺伝子診断が行われ,確診にいたった地中海熱の一例
(日本プライマリ・ケア連合学会学術大会抄録集 2018)
バセドウ病治療経過中に橋本病による甲状腺機能亢進を来した1例
(日本内科学会関東支部関東地方会 2017)
RPGRIP1L遺伝子にホモ結合性の変異を認めたネフロン癆と肝硬変の合併例
(日本腎臓学会誌 2017)

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Professional career (1)：

博士(医学) (慶應義塾大学医学部)

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