Research theme for competitive and other funds (9):
2023 - 2027 転移因子の転写と共役した細胞核構造の組織化
2020 - 2023 小分子RNAによるトランスポゾン転写抑制機構の解析
2020 - 2022 Role of retrotransposons in early embryonic development and totipotency control
2017 - 2020 Maintenance of the germ cell genome by non-coding RNA
2013 - 2018 Molecular pathways leading to epigenome formation in mammalian germ cells
2013 - 2015 新規高感度レポーター系を用いたrRNA遺伝子の種特異的転写開始機構の解析
2012 - 2015 Dynamics of sperm chromatin
2011 - 2012 ヒストンシャペロンTAF-Iによる初期胚細胞核ダイナミクスの制御機構
2009 - 2010 発生分化過程におけるヒストンシャペロンTAF-lの機能
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Papers (23):
Youjia Guo, Tomohiro Kitano, Kimiko Inoue, Kensaku Murano, Michiko Hirose, Ten D Li, Akihiko Sakashita, Hirotsugu Ishizu, Narumi Ogonuki, Shogo Matoba, et al. Obox4 promotes zygotic genome activation upon loss of Dux. eLife. 2024. 13
Akihiko Sakashita, Tomohiro Kitano, Hirotsugu Ishizu, Youjia Guo, Harumi Masuda, Masaru Ariura, Kensaku Murano, Haruhiko Siomi. Transcription of MERVL retrotransposons is required for preimplantation embryo development. Nature Genetics. 2023
Setsuko Mise-Omata, Mari Ikeda, Masaru Takeshita, Yoshifumi Uwamino, Masatoshi Wakui, Tomoko Arai, Ayumi Yoshifuji, Kensaku Murano, Haruhiko Siomi, Kensuke Nakagawara, et al. Memory B Cells and Memory T Cells Induced by SARS-CoV-2 Booster Vaccination or Infection Show Different Dynamics and Responsiveness to the Omicron Variant. Journal of immunology (Baltimore, Md. : 1950). 2022. 209. 11. 2104-2113
Ten D Li, Kensaku Murano, Tomohiro Kitano, Youjia Guo, Lumi Negishi, Haruhiko Siomi. TDP-43 safeguards the embryo genome from L1 retrotransposition. Science advances. 2022. 8. 47. eabq3806
Chikara Takeuchi, Kensaku Murano, Mitsuru Ishikawa, Hideyuki Okano, Yuka W. Iwasaki. Generation of Stable Drosophila Ovarian Somatic Cell Lines Using the piggyBac System. Methods in Molecular Biology. 2022. 2509. 143-153