Kazuhiko Maeda

マエダカズヒコ | Kazuhiko Maeda

Affiliation and department：
Job title：准教授
Homepage URL (1)： https://hostdefense.ifrec.osaka-u.ac.jp/

Research field (6)： Immunology , Laboratory animal science , Molecular biology , Medical biochemistry , Experimental pathology , Virology

Research keywords (15)： T cell , Inflammation , Knockout mouse , Omics , RNA metabolism , non-coding RNA , B cell , Antibody , Immunoglobulin gene , Acquired immunity , Innate immunity , Cell-mediated immunity , Intestinal epithelial cells , Retrovirus , APOBEC

Research theme for competitive and other funds (14)：

2023 - 2026 Mechanisms Regulating RBP-RNA Interactions and Inflammatory Responses
2020 - 2025 Comprehensive understanding of Regnase-1-mediated mRNA surveillance system
2018 - 2021 Analysis of transcription-coupled mechanism via TREX-2 component GANP
2020 - 2020 Integrated understanding of functional features of Regnase -1
2015 - 2019 Comprehensive analysis of innate immunity

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Papers (41)：

Arthur Millius, Rikuhiro G. Yamada, Hiroshi Fujishima, Kazuhiko Maeda, Daron M. Standley, Kenta Sumiyama, Dimitri Perrin, Hiroki R. Ueda. Circadian ribosome profiling reveals a role for the Period2 upstream open reading frame in sleep. Proceedings of the National Academy of Sciences. 2023. 120. 40
Kitiya Piboonprai, Arthur Millius, Mayuko Shimoda, Hiroki Tanaka, Shizuo Akira, Kazuhiko Maeda. Breaking self-regulation of Regnase-1 promotes its own protein expression. Genes to cells : devoted to molecular & cellular mechanisms. 2023. 28. 5. 383-389
Shizuo Akira, Kazuhiko Maeda. Control of RNA Stability in Immunity. Annual review of immunology. 2021. 39. 481-509
Kazuhiko Maeda, Matias J. Caldez, Shizuo Akira. Innate immunity in allergy. Allergy. 2019. 74. 9. 1660-1674
Hiroki Tanaka, Yasunobu Arima, Daisuke Kamimura, Yuki Tanaka, Noriyuki Takahashi, Takuya Uehata, Kazuhiko Maeda, Takashi Satoh, Masaaki Murakami, Shizuo Akira. Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response. Journal of Experimental Medicine. 2019. 216. 6. 1431-1449

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MISC (14)：

阪口薫雄, 前田和彦. 特別寄稿獲得免疫におけるB細胞の研究、B細胞分化・活性化、そして抗体親和性の分子機構. 感染・炎症・免疫. 2016. 6. 36-44
前田和彦, AMEEN Almofty Sarah, 下田真唯子, KUMAR Singh Shailendra, ABBAS Eid Mohammed Mansour, 池田輝政, 川畑輝哉, 小糸厚, 阪口薫雄. ヒトRNA輸送TREX-2因子GANPのHIV-1抵抗性の分子機序. 日本エイズ学会誌. 2014. 16. 4
下田真唯子, 前田和彦, 阪口薫雄. 免疫グロブリンの体細胞高頻度突然変異誘導とGANP. 臨床免疫・アレルギー科. 2014. 61. 5. 472-479
前田和彦, AMEEN Almofty Sarah, KUMAR Singh Shailendra, ABBAS Eid Mohammed Mansour, 下田真唯子, 川畑輝哉, 池田輝政, 小糸厚, 阪口薫雄. HIV感染経路における宿主因子GANPの役割. 日本エイズ学会誌. 2013. 15. 4
前田和彦, 阪口薫雄. 胚中心B細胞の高親和性成熟におけるGANPの役割. 臨床免疫・アレルギー科. 2013. 60. 2. 115-121

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Patents (1)：

炎症性腸疾患治療薬およびそのスクリーニング方法

Books (9)：

生涯教育シリーズ免疫・炎症疾患のすべて
日本医師会雑誌 2020
免疫学コア講義改訂4版
南山堂 2017 ISBN:9784525167547
エッセンシャル免疫学第3版
メディカル・サイエンス・インターナショナル 2016 ISBN:9784895928649
免疫学コア講義改訂3版
南山堂 2012 ISBN:9784525167530
新機能抗体開発ハンドブック
エヌ・ティー・エス 2012 ISBN:9784864690041

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Lectures and oral presentations (4)：

免疫担当細胞におけるシングルセル解析の有効性と実用性
(Single-Cell 2019 OSAKAセミナー株式会社エー・イー企画主催 2019)
炎症反応調節とRNA代謝システムの重要性
(オリエンタル酵母工業株式会社主催 2019)
創薬研究の新展望
(とっとりバイオフロンティア主催 2019)
免疫システムにおけるRNA代謝研究の新展望
(大塚製薬株式会社主催 2017)

Education (1)：

- 2000 Kumamoto University Graduate School, Division of Medicine

Work history (9)：

2018/08 - 現在 Osaka University WPI Immunology Frontier Research Center Associate Professor (full time)
2018/08 - 現在 Osaka University Research Institute for Microbial Diseases Associate Professor
2015/05 - 2018/07 Osaka University Research Institute for Microbial Diseases Associate Professor
2015/05 - 2018/07 Osaka University WPI Immunology Frontier Research Center Associate Professor
2011/01 - 2015/04 Kumamoto University Faculty of Life Sciences Assistant Professor

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Committee career (2)：

2023/06 - Frontiers in Immunology | Associate Editor Frontiers in Immunology | Associate Editor
2016 - 日本免疫学会評議員

Awards (2)：

2014/03 - Kumamoto Medical Association Kumamoto Medical Society Encouragement Award (Research Achievement Category)
2010 - Aegean Conferences Travel Award

Association Membership(s) (1)：

The Japanese Society for Immunology

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