Kasai Tomonari

Affiliation and department：

Research field (1)： Biomedical engineering

Research theme for competitive and other funds (6)：

2021 - 2024 Development of new boron-drugs and models for BNCT targeting malignant cells.
2019 - 2022 Preparation of and drug discovery studies by hepatobiliary pancreatic cancer stem cell models derived from organoid and induced pluripotent stem cells
2016 - 2019 Establishment and application of animal model of liver cancer stem cell using induced pluripotent stem cells
2014 - 2017 Analysis of molecular mechanisms involved in the conversion of iPSs into cancer stem cells
2013 - 2017 Development of the strategy for fundamental therapy of cancer using iPS derived Cancer Stem cell models

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Papers (55)：

Tianyun Zhou, Kazuyo Igawa, Tomonari Kasai, Takuya Sadahira, Wei Wang, Tomofumi Watanabe, Kensuke Bekku, Satoshi Katayama, Takehiro Iwata, Tadashi Hanafusa, et al. The current status and novel advances of boron neutron capture therapy clinical trials. American journal of cancer research. 2024. 14. 2. 429-447
Takafumi Shigehira, Tadashi Hanafusa, Kazuyo Igawa, Tomonari Kasai, Shuichi Furuya, Hisakazu Nishimori, Yoshinobu Maeda, Hiroyuki Michiue, Atsushi Fujimura. Particle and Heavy Ion Transport Code System-Based Microdosimetry for the Development of Boron Agents for Boron Neutron Capture Therapy. Advanced Theory and Simulations. 2023
Zaijun Zhang, Hiroaki Ishihata, Ryuto Maruyama, Tomonari Kasai, Hiroyuki Kameda, Tomoyasu Sugiyama. Deep Learning of Phase-Contrast Images of Cancer Stem Cells Using a Selected Dataset of High Accuracy Value Using Conditional Generative Adversarial Networks. International journal of molecular sciences. 2023. 24. 6
Yumi Hanai, Hiroaki Ishihata, Zaijun Zhang, Ryuto Maruyama, Tomonari Kasai, Hiroyuki Kameda, Tomoyasu Sugiyama. Temporal and Locational Values of Images Affecting the Deep Learning of Cancer Stem Cell Morphology. Biomedicines. 2022. 10. 5. 941-941
Hiroyuki Michiue, Mizuki Kitamatsu, Asami Fukunaga, Nobushige Tsuboi, Atsushi Fujimura, Hiroaki Matsushita, Kazuyo Igawa, Tomonari Kasai, Natsuko Kondo, Hideki Matsui, et al. Self-assembling A6K peptide nanotubes as a mercaptoundecahydrododecaborate (BSH) delivery system for boron neutron capture t (BNCT). Journal of controlled release : official journal of the Controlled Release Society. 2020. 330. 788-796

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MISC (23)：

Apriliana C. Khayrani, Hafizah Mahmud, Tomonari Kasai, Tsukasa Shigehiro, Aung Ko Ko Oo, Juan Du, Md. Jahangir Alam, Koji Hara, Hiroki Hamada, Yuhki Seno, et al. Development of Paclitaxel Glycoside Liposomes Conjugated with Anti-CD44 Antibody Targeting Ovarian Cancer Cells. CANCER SCIENCE. 2018. 109. 1097-1097
小野喜章, 小野喜章, 江口傑徳, 十川千春, 村上純, 藤原敏史, 藤原敏史, 笠井智成, 妹尾昌治, 佐々木朗, et al. 口腔扁平上皮癌細胞由来エクソソームに含まれる分子シャペロンについての検討. 臨床ストレス応答学会大会抄録集. 2017. 12th
Neha Nair, Arun Vaidyanath, Kenta Hoshikawa, Anna Sanchez Calle, Tomonari Kasai, Masaharu Seno. Cancer stem cells as the novel origin of cancer-associated fibroblast-like cells. CANCER RESEARCH. 2016. 76
Anna Sanchez Calle, Kenta Hoshikawa, Neha Nair, Marta Prieto-Vila, Arun Vaidyanath, Tomonari Kasai, Masaharu Seno. The significance of c-Kit protooncogene in iCSC-derived PDAC model. CANCER RESEARCH. 2016. 76
Zahra MH, Osman AMA, Agwa H, Nair N, Calle AS, Hurley L, Farag D, Kasai T, Seno M, Zahran M. Synthesis, Biological Evaluation, Docking and QSAR Studies of Some Novel Naphthalimide Dithiocarbamate Analogs as Antitumor and Anti-Inflammatory Agents. Medicinal Chemistry (Los Angeles). 2016. 6. 12. 694-703

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Patents (13)：

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Professional career (1)：

博士(農学) (岡山大学)

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