Rchr
J-GLOBAL ID：201801011444626712
Update date: Mar. 27, 2024
Monzen Satoru
モンゼン サトル | Monzen Satoru
Affiliation and department：
Research keywords (9)：
biomarker for radiosensitivity
, Extracellular vesicle
, Metabolome analysis
, Cancer bone metastasis
, bone marrow
, radiation biology
, radioprotection
, radiotherapy
, ionizing radiation
Research theme for competitive and other funds (21)：
- 2021 - 2025 最新分子生物学的アプローチによる放射線感受性メカニズムの解明
- 2021 - 2025 The radiosensitive mechanism of bone metastatic cancer cell regulated by bone turnover
- 2019 - 2022 The effective biodosimetry tool using urinal or feces components
- 2018 - 2022 がん骨転移放射線療法の新たな抗腫瘍効果・副作用マーカーの探索
- 2017 - 2019 Search for blood and fecal microRNA biomarkers that can estimate acute exposure to intestinal death
- 2016 - 2019 Investigation of body fluid biomarkers for bone marrow failure in acute radiation syndrome using metabolomics
- 2015 - 2017 Application of exosomal molecules as exposure dose assessment markers
- 2013 - 2017 Investigation of reserve capacity factor(s) in cancer patients under radioactive drug treatment .
- 2013 - 2016 Life-saving effect and mechanism of action of thrombopoietin receptor agonist in radiation-exposed individuals
- 2012 - 2016 The study of anti-tumor with anti-metastasis under combination of 4-methylumbelliferone on X-irradiation against cancer cell
- 2013 - 2015 The development of novel internal radiation dosimetry using circulating exosomal RNAs into body fluids
- 2013 - 2015 Enhancement of radiation therapy for cancer treatment by focusing on pattern recognition receptors
- 2012 - 2015 Relationship between 8-hydroxydeoxyguanosine levels in placental/umbilical cord blood and maternal/neonatal obstetric factors
- 2012 - 2014 Protective effects of a combination of multiple pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation
- 2013 - 2013 放射線作業従事者を対象とした放射線感受性を検査する実用化技術開発
- 2011 - 2012 The functional analysis of cell repair system by cytokines on humanCD34+ hematopoietic stem cells irradiated to ionizing radiation.
- 2011 - 2012 Effects of ionizing radiation on the pattern recognition receptors.
- 2010 - 2011 The development of multifunctional drug for magnetic resonance imaging diagnosis that uses metallic complex liquid crystal compound
- 2009 - 2011 The identification of factor (s) which regulate individual radiosensitivity of human hematopoietic stem/progenitor cells and its application
- 2009 - 2011 The study of new radiation therapy combined with high concentration ascorbic acid as to achieve high tumor local control rate
- 2008 - 2009 The functional analysis of exposure to a MRI-type high-strength static magnetic field stimulates megakaryocytic/erythroid hematopoiesis in CD34+ cells from human placental and umbilical cord blood
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Papers (61)：
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Yoshiaki Sato, Hironori Yoshino, Junya Ishikawa, Satoru Monzen, Masaru Yamaguchi, Ikuo Kashiwakura. Prediction of hub genes and key pathways associated with the radiation response of human hematopoietic stem/progenitor cells using integrated bioinformatics methods. Scientific reports. 2023. 13. 1. 10762-10762
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Yota Tatara, Satoru Monzen. Proteomics and secreted lipidomics of mouse-derived bone marrow cells exposed to a lethal level of ionizing radiation. Scientific reports. 2023. 13. 1. 8802-8802
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Kana Matsumoto, Yumiko Kato, Momone Hayashi, Risa Miura, Satoru Monzen, Mitsuru Chiba. Hepatic gene expression and functional changes associated with nonalcoholic steatohepatitis. Molecular medicine reports. 2022. 26. 5
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Satoru Monzen, Tatsuya Ueno, Mitsuru Chiba, Yuki Morino, Yasushi Mariya, Andrzej Wojcik, Lovisa Lundholm. Dose-dependent expression of extracellular microRNAs in HCT116 colorectal cancer cells exposed to high-dose-rate ionising radiation. Molecular and Clinical Oncology. 2022. 16. 1. 19-19
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Satoru Monzen, Yota Tatara, Yasushi Mariya, Mitsuru Chiba, Andrzej Wojcik, Lovisa Lundholm. HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum. Molecular and clinical oncology. 2020. 13. 6. 70-70
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MISC (147)：
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千葉 満, 杉山 彦斗, 門前 暁. 放射線抵抗性を獲得した急性前骨髄球性白血病細胞株HL60におけるmiRNA発現変化(Altered miRNA expression in acute promyelocytic leukemia cell line HL60 that has acquired radioresistance). 日本癌学会総会記事. 2023. 82回. 1977-1977
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山中 天聖, 門前 暁, 菊池 愛, 檜山 純太, 杉山 彦斗, 多田羅 洋太, 真里谷 靖. 前立腺がん骨転移巣の微小環境下で産生されるホスファチジルコリンと細胞特異性. 日本放射線技術学会総会学術大会予稿集. 2023. 79回. 222-222
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佐藤 亮介, 門前 暁, 上野 達也, 千葉 満, 真里谷 靖, ヴォイチク・アンドレイ. 大腸がん細胞株HCT-116にて発見された放射線損傷特異マイクロRNA遺伝子発現の特徴. 日本放射線技術学会総会学術大会予稿集. 2023. 79回. 222-222
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門前 暁, 千葉 満, 真里谷 靖. 放射線治療抵抗性を示すHER2陽性乳癌のスフィンゴミエリン代謝の特徴. 日本臨床検査医学会誌. 2022. 70. 補冊. 144-144
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千葉 満, 松本 佳菜, 門前 暁, 真里谷 靖. 子ども期の放射線被ばくに特徴的な血清中microRNA解析. 日本臨床検査医学会誌. 2022. 70. 補冊. 261-261
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Patents (4)：
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