Rchr
J-GLOBAL ID：201801013675227686   Update date: Apr. 23, 2024

OHARA TOSHIAKI

オオハラ トシアキ | OHARA TOSHIAKI
Affiliation and department：
Okayama University

About Okayama University


Research field  (1)： Clinical pharmacy
Research theme for competitive and other funds  (29)：
  • 2023 - 2027 A Novel Mechanism of Infertility through the Oral-Uterine Interaction Induced by Periodontal Infection and Inflammation
  • 2023 - 2026 AI病理診断に向けた、組織切片の厚さの簡易計測法の開発と標準化技術の確立
  • 2022 - 2026 Iron metabolism between slender non-alcoholicity fat hepatitis and arteriosclerosis-related disease
  • 2022 - 2025 Development of novel immune therapy using iron chelators via HIF activation
  • 2023 - 2024 New materials development by the functionalization of the quality of wood biomass
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Papers (93)：
  • Teruki Kobayashi, Kazuhiro Noma, Seitaro Nishimura, Takuya Kato, Noriyuki Nishiwaki, Toshiaki Ohara, Tomoyoshi Kunitomo, Kento Kawasaki, Masaaki Akai, Satoshi Komoto, et al. Near-infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Patient-Derived Xenografts using a Humanized anti-Fibroblast Activation Protein Antibody. Molecular Cancer Therapeutics. 2024
  • Masaaki Akai, Kazuhiro Noma, Takuya Kato, Seitaro Nishimura, Hijiri Matsumoto, Kento Kawasaki, Tomoyoshi Kunitomo, Teruki Kobayashi, Noriyuki Nishiwaki, Hajime Kashima, et al. Fibroblast activation protein-targeted near-infrared photoimmunotherapy depletes immunosuppressive cancer-associated fibroblasts and remodels local tumor immunity. British journal of cancer. 2024
  • Taku Noumi, Shoka Kimura, Takuro Fushimi, Shuichi Sakamoto, Kayo Nakamura, Soichiro Fushimi, Toshiaki Ohara, Shuko Mashimo, Hiroyuki Tao, Takanori Watanabe, et al. Two autopsied gastric cancer cases of rare drug-induced pneumonia associated with nivolumab plus S-1 and oxaliplatin: a case report. Journal of gastrointestinal oncology. 2024. 15. 1. 491-499
  • Naoto Hori, Hiroshi Tazawa, Yuncheng Li, Tomohiro Okura, Satoru Kikuchi, Shinji Kuroda, Toshiaki Ohara, Kazuhiro Noma, Masahiko Nishizaki, Yasuo Urata, et al. Intraperitoneal Administration of p53-armed Oncolytic Adenovirus Inhibits Peritoneal Metastasis of Diffuse-type Gastric Cancer Cells. Anticancer research. 2023. 43. 11. 4809-4821
  • Kento Kawasaki, Kazuhiro Noma, Takuya Kato, Toshiaki Ohara, Shunsuke Tanabe, Yasushige Takeda, Hijiri Matsumoto, Seitaro Nishimura, Tomoyoshi Kunitomo, Masaaki Akai, et al. PD-L1-expressing cancer-associated fibroblasts induce tumor immunosuppression and contribute to poor clinical outcome in esophageal cancer. Cancer immunology, immunotherapy : CII. 2023. 72. 11. 3787-3802
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MISC (362)：
  • 西村 星多郎, 野間 和広, 高橋 達也, 竹田 泰茂, 松本 聖, 國友 知義, 河崎 健人, 赤井 正明, 小林 照貴, 賀島 肇, et al. CAFsを標的にした光免疫療法によるドラッグデリバリー改善効果(Drug delivery improvement of CAFs targeted photoimmunotherapy). 日本癌学会総会記事. 2023. 82回. 131-131
  • 大原 利章, 陳 悦華, 王 宇沢, 濱田 祐輔, 菊地 覚次, 野間 和広, 田澤 大, 藤澤 真義, 藤原 俊義, 松川 昭博. 鉄キレート効果を持つHIF-PH阻害薬は抗腫瘍免疫応答を向上させる(HIF-PH inhibitors with iron chelating ability enhance the tumor immune response). 日本癌学会総会記事. 2023. 82回. 248-248
  • 河合 穂高, トゥ・シュエイン, 中山 真彰, 大原 利章, 長塚 仁. 口腔癌におけるCX3CL1とリンパ節転移の関係(Relationship between CX3CL1 and lymph node metastasis in oral cancer). 日本癌学会総会記事. 2023. 82回. 1421-1421
  • 宇根 悠太, 菊地 覚次, 田澤 大, 黒田 新士, 大原 利章, 野間 和広, 香川 俊輔, 藤原 俊義. 胃がん腹膜転移の生物学的解明を目的とした腹膜構造3Dモデルの開発(Development of the 3D model of peritoneum structure to explore the biology of gastric cancer peritoneal metastasis). 日本癌学会総会記事. 2023. 82回. 1858-1858
  • 尾山 貴徳, 野田 卓男, 宮田 将徳, 渡邉 宏和, 鷲尾 洋介, 吉本 順子, 大原 利章, 松川 昭博. 腕頭動脈から分岐した左総頸動脈より気管孔へ出血した一例. 日本小児外科学会雑誌. 2023. 59. 3. 723-723
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Patents (20)：
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Books (4)：
  • Development of a wood compression technology to enhance the efficiency of woody biomass fuel production.
    Clean energy 2023
  • Roller compaction method for the production of high-quality woody biomass fuel.
    2023
  • Management of dialysis operations for safety assurance and (2) Implementation of AI-based dialysis room management
    2021
  • Challenging the Next-Generation Life Innovations: Development of Novel Cancer Therapies Using Iron Removal Application.
    2014
Work history (3)：
  • 2014/05 - 現在 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Pathology and Experimental Medicine Assistant Professor
  • 2012/04 - 2014/05 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
  • 2002/04 - 2002/07 Okayama University Medical School
Committee career (2)：
  • 2023/09 - 2023/09 The 47th Annual Congress of Japanese Bioiron Society Congress President
  • 2022/10 - 2023/05 Cancers Guest editor Special Issue "The Impact of Iron Metabolism in Cancer"
Awards (5)：
  • 2023/05 - The Sanyo Broadcasting Foundation Research Award
  • 2020/10 - Ryobi Teien Memory Foundation Research Award
  • 2014/11 - Japanese Society for Gastroenterological Carcinogenesis Young Investigator Award
  • 2014/06 - Okayama Medical Association Incentive Award
  • 2014/02 - Princess Takamatsu Cancer Research Fund Prizes Research Grants
Association Membership(s) (10)：
Japanese Association for Medical Artificial Intelligence ,  THE JAPAN ESOPHAGEAL SOCIETY ,  Japanese Society for Gastroenterological Carcinogenesis ,  American Society of Clinical Oncology ,  American Association for Cancer Research ,  The Japanese BioIron society ,  The Japanese Cancer Association ,  The Japanese Society of Gastroenterological Surgery ,  Japan Surgical Society ,  The Japanese Society of Pathology
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