Research theme for competitive and other funds (6):
2022 - 2026 根本的な老化メカニズムの理解と破綻に伴う疾患機序解明
2020 - 2023 pHストレス適応を司るpH誘導型転写因子の実体解明
2020 - 2022 pH 応答生物学の創成
2019 - 2022 健康・医療の向上に向けた早期ライフステージにおける生命現象の解明
2011 - 2012 Physiologicalsignificance or redox-sensitive ion channels
2009 - 2010 TRPチャネルによる活性分子種センシングの生理的意義解明
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Papers (40):
Reiko Sakaguchi, Nobuaki Takahashi, Takashi Yoshida, Nozomi Ogawa, Yoshifumi Ueda, Satoshi Hamano, Kaori Yamaguchi, Seishiro Sawamura, Shinichiro Yamamoto, Yuji Hara, et al. Dynamic remodeling of TRPC5 channel-caveolin-1-eNOS protein assembly potentiates the positive feedback interaction between Ca2+ and NO signals. J. Biol. Chem. 2024. 107705-107705
Tomoyuki Kuwaki, Nobuaki Takahashi. TRPA1 channel in the airway underlies protection against airborne threats by modulating respiration and behaviour. J. Physiol. 2023
Tatsuya Kida, Nobuaki Takahashi (Co-first), Masayuki X. Mori, Jiacheng H. Sun, Hideto Oota, Kosuke Nishino, Takashi Okauchi, Yuta Ochi, Daisuke Kano, Ukihide Tateishi, Yasuyoshi Watanabe, Yilong Cui, Yasuo Mori, Hisashi Doi. N-Methylamide-structured SB366791 derivatives with high TRPV1 antagonistic activity: toward PET radiotracers to visualize TRPV1. RSC Medicinal Chemistry. 2022. 13. 10. 1197-1204
Akito Nakao, Yoshihiro Matsunaga, Katsumi Hayashida, Nobuaki Takahashi*. Role of Oxidative Stress and Ca2+ Signaling in Psychiatric Disorders. Front. Cell Dev. Biol. 2021. 9