Rchr
J-GLOBAL ID:201801016009038312   Update date: Nov. 22, 2024

Kosaka Tomoyuki

コウサカ トモユキ | Kosaka Tomoyuki
Affiliation and department:
Job title: Associate Professor
Other affiliations (1):
  • Yamaguchi University
Homepage URL  (2): https://ds.cc.yamaguchi-u.ac.jp/~yulmf2022/https://ds.cc.yamaguchi-u.ac.jp/~yulmf2022/en/
Research field  (4): Applied microbiology ,  Systems genomics ,  Molecular biology ,  Environmental agriculture
Research keywords  (15): Functions of Microorganisms ,  propionate oxidizing bacteria ,  methanogen ,  大腸菌 ,  prokaryote ,  metabolic mechanisms ,  genetic engineering ,  bioinformatics ,  robustness ,  thermotolerance ,  succinate oxidation ,  Formate ,  Hydrogen ,  aggregation ,  Systems biology
Research theme for competitive and other funds  (10):
  • 2023 - 2027 酵素の細胞内局在性の改変と反応場の改変によって物質生産能を改善する「酵素反応場工学」の検証
  • 2024 - 2025 Comparison and analysis of expression data and simulation results in gene knockout strains
  • 2020 - 2025 Algorithms for metabolic network design for producing useful substances
  • 2021 - 2024 Search and functional analysis of maturation genes for syntrophic propionate oxidation using genomic information
  • 2016 - 2019 Survival strategy of a cell; intra- and inter-species interaction analysis by barcode tchnology in Escherichia coli
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Papers (49):
  • Noppon Lertwattanasakul, Sornsiri Pattanakittivorakul, Sukanya Nitiyon, Minenosuke Matsutani, Akihiro Oguchi, Katsushi Hirata, Tomoyuki Kosaka, Savitree Limtong, Mamoru Yamada. Mutants with Enhanced Multi-Stress Tolerance of Kluyveromyces marxianus and Their Ability for Ethanol Fermentation. Fuels. 2023
  • Takeyuki Tamura, Ai Muto-fujita, Yukako Tohsato, Tomoyuki Kosaka. Gene Deletion Algorithms for Minimum Reaction Network Design by Mixed-Integer Linear Programming for Metabolite Production in Constraint-Based Models: gDel_minRN. Journal of Computational Biology. 2023. 30. 5. 553-568
  • Tomoyuki Kosaka, Yuka Tsushima, Yusuke Shiota, Takayuki Ishiguchi, Kazuo Matsushita, Minenosuke Matsutani, Mamoru Yamada. Membrane Potential-requiring Succinate Dehydrogenase Constitutes the Key to Propionate Oxidation and Is Unique to Syntrophic Propionate-oxidizing Bacteria. Microbes and Environments. 2023. 38. 2. ME22111-n/a
  • Yushi Takehara, Isamu Fijikawa, Akihiro Watanabe, Ayumi Yonemura, Tomoyuki Kosaka, Kosei Sakane, Kiyoshi Imada, Kazunori Sasaki, Hiroshi Kajihara, Shoji Sakai, et al. Molecular Analysis of MgO Nanoparticle-Induced Immunity against Fusarium Wilt in Tomato. International Journal of Molecular Sciences. 2023. 24. 3. 2941-2941
  • Takao Koeduka, Bunta Watanabe, Konomi Shirahama, Masaru Nakayasu, Shiro Suzuki, Takumi Furuta, Hideyuki Suzuki, Kenji Matsui, Tomoyuki Kosaka, Shin-ichi Ozaki. Biosynthesis of dillapiole/apiole in dill ( Anethum graveolens ): characterization of regioselective phenylpropene O -methyltransferase. The Plant Journal. 2022. 113. 3. 562-575
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MISC (9):
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Patents (2):
Books (5):
  • Kluyveromyces marxianus as a Platform in Synthetic Biology for the Production of Useful Materials. In: Darvishi Harzevili, F. (eds) Synthetic Biology of Yeasts.
    2022 ISBN:9783030896805
  • Potential of thermotolerant ethanologenic yeasts isolated from ASEAN countries and their application for high temperature fermentation. In Fuel ethanol production from sugarcane (eds. Basso TP, Basso LC)
    IntechOpen, Croatia 2018
  • Survival Strategy of Escherichia coli in Stationary Phase. In Escherichia coli - recent advances on physiology, pathogenesis and biotechnological applications (ed. Samie A)
    InTech, Croatia 2017
  • Menaquinone as Well as Ubiquinone as a Crucial Component in the Escherichia coli Respiratory Chain. In Chemical Biology, (ed. Deniz Ekinci)
    Intech open access publisher, Croatia. 2012
  • Small non-coding RNAs and their involvement in regulation of various biological processes in Escherichia coli and other bacteria. In Y. Sadaiye, K. Matsumoto (eds.), Escherichia coli and Bacillus subtilis; the frontiers of molecular microbiology revisi
    Research Signpost, Canada. 2012
Lectures and oral presentations  (167):
  • Zymomonas mobilis における高温限界温度を高める分子機構
    (日本生物工学会西日本支部大会2024 (第7回講演会) 2024)
  • グラム陽性細菌におけるコハク酸脱水素酵素 FAD 共有結合機構の解明
    (日本生物工学会西日本支部大会2024 (第7回講演会) 2024)
  • 共生的プロピオン酸酸化系微生物の大腸菌でのギ酸トランスポーターの機能解析
    (日本微生物生態学会 第37回広島大会 2024)
  • Genomic information analysis for extraction and visualization of sets of genes involved in target enzyme function
    (The Society for Biotechnology, Japan / Annual Meeting 2024 2024)
  • Research and application of procedure for heterologous formate transporter characterization of uptaking function in Escherichia coli
    (Japan Society for Bioscience, Biotechnology, and Agrochemistry 2024 Annual Meeting / 100th Anniversary Meeting 2024)
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Education (3):
  • 2000 - 2003 Graduate school of Kyushu University Faculty of Agriculture
  • 1998 - 2000 九州大学大学院 生物資源環境科学研究科 農芸化学専攻
  • 1994 - 1998 Kyushu University School of Agriculture
Professional career (1):
  • Ph.D (Agriculture) (Kyushu University)
Work history (7):
  • 2021/04 - 現在 Yamaguchi University Research Center for Thermotolerant Microbial Resources (RCTMR), Advanced Science and Innovation Research Center, Organization for Research Initiatives Associate Professor
  • 2019/07 - 現在 Yamaguchi university Graduate School of Sciences and Technology for Innovation, Yamaguchi University Associate professor
  • 2016/04 - 2019/06 Yamaguchi University Department of Biological Chemistry, Collage of Agriculture, Graduate School of Science and Technology for Innovation Assistant professor
  • 2010/02 - 2016/03 YAMAGUCHI UNIVERSITY Faculty of Agriculture Assistant Professor
  • 2006/10 - 2010/03 Japan Science and Technology Agency
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Association Membership(s) (3):
Japanese Society of Microbial Ecology ,  Japan Society for Bioscience, Biotechnology, and Agrochemistry ,  The Society for Biotechnology, Japan
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