Miwa Yuko

ミワユウコ | Miwa Yuko

Affiliation and department：

Research field (1)： Immunology

Research keywords (5)： BKウイルス , ABO血液型移植 , 凝固系 , 異種移植 , 移植免疫

Research theme for competitive and other funds (16)：

2021 - 2024 非翻訳RNAに着目したCNI腎症早期発見システムの構築
2021 - 2024 Identification of Indirect Alloreactive T-Cells and Application to Monitoring of anti-Donor Antibody Sensing
2020 - 2023 Identification and control of follicular helper T cell clonotype related to donor specific HLA antibody production
2020 - 2023 From treatment to prevention: development of innovative immune regulation based on epitope/paratope analysis
2019 - 2022 腎移植におけるBKウイルスモニタリングシステムによるグラフト長期生着への取り組み

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Papers (34)：

Iwasaki Kenta, Tomosugi Toshihide, Sekiya Takashi, Sakamoto Shintaro, Miwa Yuko, Okada Manabu, Hiramitsu Takahisa, Goto Norihiko, Narumi Shunji, Watarai Yoshihiko, et al. Estimation of Sensitization Status in Renal Transplant Recipients by Assessing Indirect Pathway CD4+ T cell Response to Donor Cell-pulsed Dendritic Cell. Transplantation. 2023. Publish Ahead of Print. 5. 1079-1088
Shuichi Shimabukuro, Kenta Iwasaki, Shintaro Kawai, Takayuki Shirouzu, Yuko Miwa, Yusuke Iida, Fumiaki Nakajima, Kosei Horimi, Yutaka Matsuoka, Satoshi Ashimine, et al. Improved detection of donor-specific HLA-class II antibody in kidney transplant recipients by modified immunocomplex capture fluorescence analysis. Transplant immunology. 2021. 67. 101418-101418
Kenta Iwasaki, Hiroshi Hamana, Hiroyuki Kishi, Takayuki Yamamoto, Takahisa Hiramitsu, Manabu Okad, Toshihide Tomosugi, Asami Takeda, Shunji Narumi, Yoshihiko Watarai, et al. The suppressive effect on CD4 T-cell alloresponse against endothelial HLA-DR via PD-L1 induced by anti-A/B ligation. Clinical and experimental immunology. 2020
Akihiro Maenaka, Iwasaki Kenta, Akinobu Ota, Yuko Miwa, Wataru Ohashi, Kosei Horimi, Yutaka Matsuoka, Masafumi Ohnishi, Kazuharu Uchida, Takaaki Kobayashi. Interferon-γ-induced HLA Class II expression on endothelial cells is decreased by inhibition of mTOR and HMG-CoA reductase. FEBS Open Bio. 2020
Shintaro Sakamoto, Kenta Iwasaki, Toshihide Tomosugi, Matthias Niemann, Eric Spierings, Yuko Miwa, Kosei Horimi, Asami Takeda, Norihiko Goto, Shunji Narumi, et al. Analysis of T and B Cell Epitopes to Predict the Risk of de novo Donor-Specific Antibody (DSA) Production After Kidney Transplantation: A Two-Center Retrospective Cohort Study. Frontiers in immunology. 2020. 11. 2000-2000

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MISC (147)：

前仲亮宏, 岩崎研太, 三輪祐子, 堀見孔星, 松岡裕, 友杉俊英, 奥村真衣, 打田和治, 斎藤寛子, 小林孝彰. 内皮細胞内誘導性HLA class IIは免疫抑制剤により制御される. MHC: Major Histocompatibility Complex. 2018. 25. 2. 133-133
友杉俊英, 小林孝彰, 奥村真衣, 松岡裕, 堀見孔星, 三輪祐子, 岩崎研太, 打田和治, 渡井至彦. De novo DSA産生抑制に関与し得るHLAアリルの検討. MHC: Major Histocompatibility Complex. 2018. 25. 2. 135-135
岩崎研太, 三輪祐子, 打田和治, 堀見孔星, 松岡裕, 村口篤, 岸裕幸, 浜名洋, 小林孝彰. 内皮細胞HLA-class II DRとアロ応答するCD4 T細胞は、anti-A/B抗体接着により抑制される. MHC: Major Histocompatibility Complex. 2018. 25. 1. 50-55
松岡裕, 岩崎研太, 堀見孔星, 河野あゆみ, 相原祐子, 三輪祐子, 打田和治, 小林孝彰. 腎移植後ウイルス感染抑制を考慮した免疫抑制薬の選択. 日本臨床腎移植学会雑誌. 2017. 5. 2. 238-238
岩崎研太, 前仲亮宏, 三輪祐子, 打田和治, 斎藤寛子, 小林孝彰. 内皮細胞HLAの発現抑制シグナルの同定とそれを可能にする薬剤探索. Organ Biology. 2017. 24. 3. 40-40

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Education (2)：

2005 - 2009 名古屋大学大学院医学研究科分子総合医学分子生物学
1989 - 1993 Kobe University

Professional career (1)：

医学博士 (名古屋大学)

Work history (5)：

2016/04 - 現在 Aichi Medical University
2015/12 - 2016/03 Aichi Medical University
2015/04 - 2015/11 名古屋大学大学院医学研究科消化器外科受託研究プロジェクト特任助教
2012/04 - 2015/03 名古屋大学大学院医学研究科移植免疫学寄附講座研究員
2009/12 - 2012/03 名古屋大学大学院医学研究科免疫機能制御学寄附講座ポスドク

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