Rchr
J-GLOBAL ID:201801017685646275   Update date: Jan. 30, 2024

Masaki Takahashi

Masaki Takahashi
Affiliation and department:
Research field  (6): Medical biochemistry ,  Molecular biology ,  Neuroscience - general ,  Biomaterials ,  Biomedical engineering ,  Molecular biochemistry
Research theme for competitive and other funds  (10):
  • 2022 - 2024 Development of visualized nano-DDS agents for brain by aptamers and quantum dots
  • 2021 - 2023 AIアプタマー創薬プロジェクト
  • 2020 - 2022 Development of multi-functional siRNA-aptamer chimera for virus infections
  • 2018 - 2020 人工知能技術を用いた革新的アプタマー創薬システムの開発
  • 2017 - 2018 ウイルス様粒子を新規材料とした膜タンパク質結合RNAアプタマー創製法の開発
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Papers (28):
  • Masaki Takahashi, Yoshifumi Hashimoto, Yoshikazu Nakamura. Anti-TGF-β1 aptamer enhances therapeutic effect of tyrosine kinase inhibitor, gefitinib, on non-small cell lung cancer in xenograft model. Molecular Therapy - Nucleic Acids. 2022
  • Masaki Takahashi. Nucleic Acid Aptamers Emerging as Modulators of G-Protein-Coupled Receptors: Challenge to Difficult Cell Surface Proteins. Cells. 2022. 11. 11. 1825-1825
  • Masaki Takahashi, Ryo Amano, Michiru Ozawa, Anna Martinez, Kazumasa Akita, Yoshikazu Nakamura. Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2. Proceedings of the National Academy of Sciences. 2021. 118. 18. e2019497118-e2019497118
  • Masashi Fukuoka, Masaki Takahashi, Hiromi Fujita, Tomoko Chiyo, H. Akiko Popiel, Shoko Watanabe, Hirokazu Furuya, Miho Murata, Keiji Wada, Takashi Okada, et al. Supplemental Treatment for Huntington's Disease with miR-132 that Is Deficient in Huntington's Disease Brain. Molecular Therapy - Nucleic Acids. 2018. 11. 79-90
  • Masaki Takahashi. Aptamers targeting cell surface proteins. Biochimie. 2018. 145. 63-72
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MISC (9):
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Patents (7):
Association Membership(s) (3):
Oligonucleotide Therapeutics Society ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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