Miyaoka Yuichiro (Ichi)

ミヤオカユウイチロウ | Miyaoka Yuichiro (Ichi)

Affiliation and department：
Job title： Project Leader
Other affiliations (2)：

Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Affiliated Associated Professor
Ochanomizu University Graduate School of Humanities and Sciences Affiliated Associated Professor

Homepage URL (2)： https://www.igakuken-regmed.com/ , https://www.igakuken-regmed.com

Research field (3)： Experimental pathology , Genomics , Molecular biology

Research keywords (4)： Regenerative medicine , CRISPR-Cas9 , Genome editing , iPS cells

Research theme for competitive and other funds (6)：

2024 - 2027 細胞種により異なる倍数性の意義をiPS細胞モデルにより追究する
2020 - 2023 Development of non-random genome editing technology for therapeutic applications
2020 - 2022 Single-cell level analysis of genome editing outcomes for medical applications
2017 - 2020 Genome editing technology that enables gene correction therapies
2010 - 2012 Cellular interaction in liver development and pathogenesis

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Papers (28)：

Gou Takahashi, Minato Maeda, Kayoko Shinozaki, Gakuro Harada, Saburo Ito, Yuichiro Miyaoka. High-throughput robotic isolation of human iPS cell clones reveals frequent homozygous induction of identical genetic manipulations by CRISPR-Cas9. bioRxiv. 2024
Tomoko Kato-Inui, Gou Takahashi, Terumi Ono, Yuichiro Miyaoka. Fusion of histone variants to Cas9 suppresses non-homologous end joining. PLOS ONE. 2024
Mashiat Mustaq, Naeem Ahmed, Sazan Mahbub, Clara Li, Yuichiro Miyaoka, Julia TCW, Shea Andrews, Md. Shamsuzzoha Bayzid. Predicting Alzheimer’s Trajectory: A Multi-PRS Machine Learning Approach for Early Diagnosis and Progression Forecasting. medRxiv. 2023
Gou Takahashi, Yuichiro Miyaoka. Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS. STAR protocols. 2023. 4. 3. 102364-102364
Martina de Majo, Mark Koontz, Elise Marsan, Nir Salinas, Arren Ramsey, Yien-Ming Kuo, Kyounghee Seo, Huinan Li, Nina Dräger, Kun Leng, et al. Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology. Stem cell reports. 2023

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MISC (8)：

中島一徹, 中島一徹, 宮岡佑一郎, 宮岡佑一郎. CRISPR-Cas9 and its medical applications. 月刊臨床免疫・アレルギー科. 2021. 76. 4
堀内泰江, 石川充, 小池伸, 江越正敏, 小幡菜々子, 畠中真依, 許絲茵, 鳥海和也, 宮下光弘, 勝田奈那, et al. カルボニルストレス性統合失調症患者iPS細胞由来グリア細胞の解析. 統合失調症研究. 2020. 10. 1
宮岡佑一郎. ゲノム編集の新技術【一塩基置換による疾患モデル細胞作製】. 月刊細胞. 2019. 51. 3
宮岡佑一郎. 一塩基置換をもつヒトiPS細胞の単離. 実験医学. 2017. 35. 9
Miller Huang, Lauren K. McHenry, Matthew L. Miller, Grace E. Kim, Branden S. Moriarity, Yuichiro Miyaoka, Marianne E. Bronner, David A. Largaespada, Bruce R. Conklin, Hanlee P. Ji, et al. Human stem cell-based model of MYCN-driven neuroblastoma. CANCER RESEARCH. 2015. 75

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Patents (1)：

Books (5)：

ゲノム編集の最新技術と医薬品・遺伝子治療・農業・水畜産物・有用物質生産への活用
技術情報協会 2023 ISBN:9784861049781
ゲノム編集技術 : 実験上のポイント/産業利用に向けた研究開発動向と安全性周知
情報機構 2023 ISBN:9784865022421
ゲノム編集技術を応用した製品開発とその実用化
技術情報協会 2021 ISBN:9784861048272
ゲノム編集実験スタンダード : 完全版 : CRISPR-Cas9の設計・作製と各生物種でのプロトコールを徹底解説
羊土社 2019 ISBN:9784758122443
トコトンやさしいゲノム編集の本
日刊工業新聞社 2019 ISBN:9784526079641

Professional career (1)：

Awards (4)：

2024/03 - Japanese Society for Regenerative Medicine Excellent Presentation Award at the 23rd Congress of the Japanese Society for Regenerative Medicine
2021/02 - AMED and NYAS AMED and NYAS Interstellar Initiative Workshop Outstanding Team Presentation Award
2019/04 - MEXT The MEXT Young Scientists’ Prize
2014/05 - Gladstone Institute of Cardiovascular Disease Postdoctoral Fellow Award for Scientific Excellence

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