Tanaka Toru

タナカトオル | Tanaka Toru

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Pharmaceuticals - health and biochemistry , Molecular biology

Research keywords (4)： translational regulation , YB-1 , tau , Alzheimer's disease

Research theme for competitive and other funds (1)：

Papers (13)：

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MISC (2)：

Toru Tanaka, Hiroaki Saito, Shinichi Miyairi, Shunsuke Kobayashi. 7-Hydorxyindirubin is capable of specifically inhibiting anticancer drug-induced YB-1 nuclear translocation without showing cytotoxicity in HepG2 hepatocellular carcinoma cells. Biochemical and Biophysical Research Communications. 2021. 544. 15-21
Toru Tanaka, Sachiyo Ohashi, Akihiko Takashima, Shunsuke Kobayashi. Glutamate-responsive translation of dendritic GSK3β mRNA triggers a cycle for amplification of reactivated preexisting GSK3β that is indispensable for tau hyperphosphorylation. Neurochemistry International. 2020. 139. 104808-104808

Lectures and oral presentations (27)：

Effect of calcium ions on the aggregation of highly phosphorylated tau
(2024)
A novel 3'-UTR variant of KANSL1 mRNA has a region complementary to tau mRNA and activates its translation.
(2023)
樹状突起におけるTauの局所翻訳と過剰リン酸化
(日本薬学会第143年会 2023)
Dendritic distribution of CDK5 mRNA and p35 mRNA, and glutamate-responsive increase of CDK5/p25 complex contribute to Tau hyperphosphorylation
(The 45th Annual Meeting of the Molecular Biology Society of Japan 2022)
Specific inhibition of YB-1 nuclear translocation and cancer exacerbation-related gene expression by indirubin derivatives
(日本薬学会第142年会 2022)

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Professional career (1)：

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