Ikumi Katano

Research theme for competitive and other funds (4)：

2022 - 2025 ヒトミクログリアが自然発生するヒト化マウスを用いた無菌環境での脳恒常性破綻の解明
2016 - 2019 Development of in vivo cytotoxicity assay system using humanized mice maintaining human mature NK cells for long-term
2013 - 2016 Development of in vivo cytotoxicity assay system using humanized mice increasing human natural killer cells
2010 - 2015 Development of experimentation systems related to personalized medicine using humanized NOG mice

Papers (41)：

Ito R, Katano I, Kwok IWH, Ng LG, Ida-Tanaka M, Ohno Y, Mu Y, Morita H, Nishinaka E, Nishime C, et al. Efficient differentiation of human neutrophils with recapitulation of emergency granulopoiesis in human G-CSF knockin humanized mice. Cell reports. 2022
Ikumi Katano, Asami Hanazawa, Iyo Otsuka, Takuya Yamaguchi, Misa Mochizuki, Kenji Kawai, Ryoji Ito, Motohito Goto, Takahiro Kagawa, Takeshi Takahashi. Development of a novel humanized mouse model for improved evaluation of in vivo anti-cancer effects of anti-PD-1 antibody. Scientific reports. 2021. 11. 1. 21087-21087
Ryoji Ito, Ikumi Katano, Iyo Otsuka, Takeshi Takahashi, Hiroshi Suemizu, Mamoru Ito, Peter J Simons. Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice. International immunology. 2021. 33. 3. 183-189
Takuya Yamaguchi, Ikumi Katano, Iyo Otsuka, Ryoji Ito, Misa Mochizuki, Motohito Goto, Takeshi Takahashi. Generation of Novel Human Red Blood Cell-Bearing Humanized Mouse Models Based on C3-Deficient NOG Mice. Frontiers in immunology. 2021. 12. 671648-671648
Yuyo Ka, Ikumi Katano, Eiko Nishinaka, Jochen Welcker, Misa Mochizuki, Kenji Kawai, Motohito Goto, Kayo Tomiyama, Tomoyuki Ogura, Taichi Yamamoto, et al. Improved engraftment of human peripheral blood mononuclear cells in NOG MHC double knockout mice generated using CRISPR/Cas9. Immunology letters. 2021. 229. 55-61

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MISC (3)：

A. Miyamoto, Katano, I, Y. Kikuchi, B. Tsuda, Y. Tokuda, M. Ito, S. Habu, Y. Kametani. The specific antibody production against HER2 peptide CH401MAP in NOG-IL4-Tg mice. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 1218-1218
Caroline Mignard, Jean-Francois Mirjolet, Olivier Duchamp, Yasuyuki Ohnishi, Ikumi Katano, Mamoru Ito. Pharmacodynamic evaluation of ADCC mediated effects in humanized IL2 or IL15 NOG mice models. CANCER RESEARCH. 2014. 74. 19
Caroline Mignard, Olivier Duchamp, Jean-Francois Mirjolet, Yasuyuki Ohnishi, Ikumi Katano, Mamoru Ito. In vivo ADCC-mediated antitumor activity study with new preclinical humanized models. MOLECULAR CANCER THERAPEUTICS. 2013. 12. 11

Professional career (1)：

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