2021 - 2024 Clarify the role of mitochondria function on the development of fatty liver and hepatic carcinogenesis by targeting Apop-1
2019 - 2022 The molecular mechanism of the inhibitory effect of liver cancer development via inter-organ relationship by regular exercise: its application to cancer prevention
2016 - 2019 The mechanism of obesity-associated liver cancer progression through cytokine cross-talk in tumor microenvironment.
2014 - 2019 Aging and anti-aging mechanisms in niche-hematopoietic stem cell interaction
2015 - 2017 The effect of regular exercise on obesity-associated liver cancer from the aspect of gut microbiota and lipid metabolites
2011 - 2015 細胞老化シグナルからみた慢性炎症と癌進展の新しい発症メカニズムの解明
2011 - 2014 The molecular mechanism of senescence-associated prolongation of inflammatory signaling and its effect on cancer micro-environments.
2010 - 2011 メタボリックストレス応答におけるCDKインヒビターの役割
2008 - 2010 Mechanism of Tumor formation by deregulated circadian rhythm and strategy for its prevention
2008 - 2009 分子イメージングを利用したCDKインヒビターp21の生体内機能の解明
2007 - 2008 The regulation and abnormalities of the epigenetics on epidermal keratinocytes
2005 - 2007 Analysis and pathophysiology of dysregulated expression of the Noxl gene using Noxl knockout mice
2005 - 2006 Molecular abnormalities of cell cycle regulations in epidermal keratinocytes for the clinical applications
2004 - 2006 Induction of p16^<INK4a> gene expression by oncogenic stress is involved in the tumor suppression mechanism of skin cancer
Hanh Vinh Ngo, Thuy Thi Thanh Le, Hieu Ngoc Vu, Hai Hoang, Hiroko Ikenaga, Misako Sato-Matsubara, Sawako Uchida-Kobayashi, Hayato Urushima, Khanh Van Nguyen, Ha Thi Nguyen, et al. Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40-CD40L Linkage. The American journal of pathology. 2024
Yuki Yamamoto, Tomonori Kamiya, Megumu Yano, Vu Thuong Huyen, Masahiro Oishi, Miki Nishio, Akira Suzuki, Kishiko Sunami, Naoko Ohtani. Oral Microbial Profile Analysis in Patients with Oral and Pharyngeal Cancer Reveals That Tumoral Fusobacterium nucleatum Promotes Oral Cancer Progression by Activating YAP. Microorganisms. 2023. 11. 12
Akino Mori, Masakazu Umezawa, Kyohei Okubo, Tomonori Kamiya, Masao Kamimura, Naoko Ohtani, Kohei Soga. Visualization of hydrocarbon chain length and degree of saturation of fatty acids in mouse livers by combining near-infrared hyperspectral imaging and machine learning. Scientific reports. 2023. 13. 1. 20555-20555
Masaki Takasugi, Naoko Ohtani, Kazuaki Takemura, Stephan Emmrich, Frances T Zakusilo, Yuya Yoshida, Nobuyuki Kutsukake, John N Mariani, Martha S Windrem, Devin Chandler-Militello, et al. CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance. Cell reports. 2023. 42. 9. 113130-113130
Naoko Ohtani, Tomonori Kamiya, Norifumi Kawada. Recent updates on the role of the gut-liver axis in the pathogenesis of NAFLD/NASH, HCC, and beyond. Hepatology communications. 2023. 7. 9
Gut-Liver axis-mediated mechanism of obesity-associated hepatocellular carcinoma development
(2019 Cold Spring Harbor Asia Conference LIVER, BIOLOGY, DISEASES & CANCER 2019)
The Mechanism of Obesity-associated Liver Cancer Progression
(The 50th Commemorial International Symposium of The Princess Takamatsu Cancer Research Fund New Horizons for Cancer Research and Precision Medicine 2019)
