Research field (3):
Cell biology
, Home economics, lifestyle science
, Functional biochemistry
Research keywords (4):
酸素
, Heme
, 遺伝性疾患
, Porphyria
Research theme for competitive and other funds (11):
2024 - 2027 末梢感染による脳内局所炎症が倦怠感を惹起する分子・神経基盤の解明
2020 - 2025 Elucidation of the neural and molecular basis of functional recovery in the ventral striatum after spinal cord injury in non-human primates
2020 - 2023 再生医療・細胞治療における安全性向上を目指した腫瘍形成制御法の開発研究
2017 - 2020 Establishment of novel transgene for in vivo cell tracking by fluorescent imaging
2015 - 2020 Elucidation of role of nucleus accumbens for neural circuit reorganization during motor function recovery
2011 - 2013 Transcription of TSPO gene under the brain inflammation
2009 - 2011 Neuronal and biological bases of the motivation in rehabilitation
2009 - 2010 Control of tumor formation after transplantation in regenerative therapy with genetic engineering methods
2007 - 2009 Molecular basis for sociality associated with gene environmental interaction mechanism
2007 - 2008 Transcriptional regulation of the neuroglobin gene expression in neural cells
2002 - 2005 Heme応答性遺伝子発現に関する研究
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Papers (38):
Takatsugu Kasahara, Tsung-Che Chang, Hiromasa Yoshioka, Sayaka Urano, Yasuko Egawa, Michiko Inoue, Tsuyoshi Tahara, Koji Morimoto, Ambara R. Pradipta, Katsunori Tanaka. Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein. Chemical Science. 2024. 15. 9566-9573
Tsuyoshi Tahara, Shuhei Takatani, Mieko Tsuji, Nina Shibata, Nami Hosaka, Michiko Inoue, Masahiro Ohno, Daiki Ozaki, Aya Mawatari, Yasuyoshi Watanabe, et al. Characteristic Evaluation of a 11C-Labeled Leucine Analog, l-α-[5-11C]methylleucine, as a Tracer for Brain Tumor Imaging by Positron Emission Tomography. Molecular pharmaceutics. 2023. 20. 3. 1842-1849
Danxi Li, Di Hu, Yuta Ochi, Wakiko Arakaki, Aya Mawatari, Mika Shigeta, Yuping Wu, Emi Hayashinaka, Hiroyuki Neyama, Tsuyoshi Tahara, et al. Regional neuroinflammation induced by peripheral infection contributes to fatigue-like symptoms: a [18F]DPA-714 positron emission tomography study in rats. Frontiers in immunology. 2023. 14. 1261256-1261256
Miho Shukuri, Aya Mawatari, Shuhei Takatani, Tsuyoshi Tahara, Michiko Inoue, Wakiko Arakaki, Masahiro Ohno, Hisashi Doi, Hirotaka Onoe. Synthesis and Preclinical Evaluation of 18F-Labeled Ketoprofen Methyl Esters for Cyclooxygenase-1 Imaging in Neuroinflammation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2022. 63. 11. 1761-1767
Shuhei Takatani, Tsuyoshi Tahara, Mieko Tsuji, Daiki Ozaki, Nina Shibata, Yoshinobu Hashizume, Masaaki Suzuki, Hirotaka Onoe, Yasuyoshi Watanabe, Hisashi Doi. Synthesis of L-[5-11 C]Leucine and L-α-[5-11 C]Methylleucine via Pd0 -mediated 11 C-Methylation and Microfluidic Hydrogenation: Potentiality of Leucine PET Probes for Tumor Imaging. ChemMedChem. 2021. 16. 21. 3271-3279
Tanaka Katsunori, Minami Kaori, Siwu Eric R. O, Masuyama Tatsuro, Koyama Koichi, Yokoi Satomi, Hasegawa Koki, Tahara Tsuyoshi, Mizuma Hiroshi, Nozaki Satoshi, et al. Azaelectrocyclization-Based Labeling of Proteins and Cell Surfaces: Application to Noninvasive Imaging of N-Glycans. Symposium on the Chemistry of Natural Products, symposium papers. 2010. 52. 0. 25-30