2018 - 2021 Novel approaches for treatment of addiction after social defeat stress
2018 - 2021 精神疾患への静脈内鎮静法の安全性の検証と新たな歯科治療ストレス軽減法の開発
2017 - 2019 Verification of the safety of intravenous sedation to patients with dementia and depression, and development of novel stress mitigation method
2016 - 2019 Investigation of dopamine neurocircuits to identify novel therapeutic targets in psychiatric disorders
2017 - 2019 Verification of the safety of intravenous sedation to patients with dementia and depression, and development of novel stress mitigation method
2016 - 2019 Investigation of dopamine neurocircuits to identify novel therapeutic targets in psychiatric disorders
2015 - 2018 Does oxdative stress reaction in nucleus accumbes exacerbate cocaine addiction after social defeat stress?
2015 - 2018 Development of new dental treatment stress reduction method from higher brain function
2015 - 2018 Does oxdative stress reaction in nucleus accumbes exacerbate cocaine addiction after social defeat stress?
2015 - 2018 Development of new dental treatment stress reduction method from higher brain function
2014 - 2017 Regulation of reward-related neural pathways and behavior by ghrelin
2014 - 2017 Regulation of reward-related neural pathways and behavior by ghrelin
2015 - 2016 グレリンによる報酬関連行動の調節とその脳内神経伝達機構の解明
2012 - 2015 Development of new dental treatment stress reduction method from the brain neural network mechanism
2012 - 2015 Development of new dental treatment stress reduction method from the brain neural network mechanism
2011 - 2012 グレリンによる食物報酬の調節とその脳内機構の解明
2010 - 2012 Central neural regulation of food preference by ghrelin
2010 - 2012 Clinical and basic studies on the dynamics of ghrelin in Rett syndrome (RTT) together with a pilot-study on the clinical implication of ghrelin for the treatment of RTT-patients.
2009 - 2011 Effects of intravenous sedation on higher brain function and development of new intravenous sedatives
2007 - 2008 Dose aromatase regulate the feeding behavior and induce the sexual difference on appetite?
2007 - 2008 Development of new stress reduction method in odontotherapy from brain neural net work mechanism
2006 - 2007 Map of dopamine signaling in the neostriatum under normal and pathophysiological conditions
2005 - 2006 Effects of intravenous sedatives on higher brain function and basic research of development of new intravenous sedatives
2005 - 2006 Effects of intravenous sedatives on higher brain function and basic research of development of new intravenous sedatives
2005 - 2006 外傷性神経損傷に対する神経幹細胞移植の細胞再生および機能再建メカニズム解析
1998 - 1999 Effects of Stress on Brain Neuronal Network and Modification of Benzodiazepines and Nitrous Oxide
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Papers (39):
Ryusuke Sin, Naoki Sotogaku, Yoshinori N. Ohnishi, Takahide Shuto, Mahomi Kuroiwa, Yukie Kawahara, Keita Sugiyama, Yuki Murakami, Masaaki Kanai, Hiroshi Funakoshi, et al. Inhibition of STAT-mediated cytokine responses to chemically-induced colitis prevents inflammation-associated neurobehavioral impairments. Brain, Behavior, and Immunity. 2023
Yuki Kishikawa, Yukie Kawahara, Yoshinori N. Ohnishi, Naoki Sotogaku, Tomoko Koeda, Hiroshi Kawahara, Akinori Nishi. Dysregulation of dopamine neurotransmission in the nucleus accumbens in immobilization-induced hypersensitivity. Frontiers in Pharmacology. 2022. 13
Yukie Kawahara, Yoshinori N Ohnishi, Yoko H Ohnishi, Hiroshi Kawahara, Akinori Nishi. Distinct Role of Dopamine in the PFC and NAc During Exposure to Cocaine-Associated Cues (selected as EDITOR'S CHOICE)). International Journal of Neuropsychopharmacology. 2021. 24. 12. 988-1001
Keita Sugiyama, Mahomi Kuroiwa, Takahide Shuto, Yoshinori N Ohnishi, Yukie Kawahara, Yuta Miyamoto, Takaichi Fukuda, Akinori Nishi. Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021. 41. 30. 6388-6414
OHNISHI Yoshinori, KAWAHARA Yukie, KISHI Yuki, OHNISHI Yoko, NISHI Akinori. What methods are physiologically or pharmacologically effective for attracting female mice?. 日本薬理学会年会要旨集(Web). 2022. 95th
KAWAHARA Yukie, OHNISHI Yoshinori, OHNISHI Yoko, KAWAHARA Hiroshi, NISHI Akinori. Distinct role of dopamine in the PFC and NAc during exposure to cocaine-associated cues. 日本薬理学会年会要旨集(Web). 2022. 95th
KAWAHARA Yukie, OHNISHI Yoshinori, OHNISHI Yoko, KAWAHARA Hiroshi, NISHI Akinori. Distinct role of dopamine in the PFC and NAc in retrieval of cocaine reward memory. 日本薬理学会年会要旨集(Web). 2021. 94th
大西克典, 河原幸恵, 大西陽子, 西昭徳. Is male mouse attractiveness inherited?. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
The role of metacognition in male mice attractiveness
(The 77th Southwest Meeting of the Japanese Pharmacological Society 2024)
Ghrelin restores dopamine response via D1 receptor signaling in the PFC in MecP2-deficient mice, a model of Rett syndrome, and improves cognitive deficits
(The 77th Southwest Meeting of the Japanese Pharmacological Society 2024)
Role of alcohol in male mouse attractiveness
(NEURO2024 2024)
Does cocaine-induced aggravation of depression alter mate attractiveness in males?
(CINP 35th World Congress of Neuropsychopharmacology 2024)
Effect of cocaine on male mice attractiveness and social ranking
(The 97th Annual Meeting of the Japanese Pharmacological Society 2023)
1991 - 1995 Kyushu Dental University Graduate School of Dentistry
1985 - 1991 Kyushu Dental University Faculty of Dentistry School of Dentistry
Professional career (1):
歯学博士 (九州歯科大学)
Work history (4):
2016/04 - 現在 Kurume University School of Medicine Reserach Associate
2007/11 - 2016/03 Kurume University School of Medicine Research Associate
2003/04 - 2008/03 Kurume University School of Medicine Research Associate
1996/04 - 2003/03 University of Groningen Center for Pharmacy Research Fellow
Committee career (5):
2019/04 - 現在 JPS Task Force Member
2012/11 - 現在 日本神経精神薬理学会 学術評議委員
2004/04 - 現在 日本薬理学会 学術評議員
2022/09 - 2024 The Japanese Parmacological Society a representative
2022/03 - 2022/12 Japan Basic Clinical Pharmacology Week 2022 Program committee
Awards (6):
2022/12 - JPW2022 (Japan Basic and Clinical Pharmacology) Excellent Poster Awards Ghrelin restores the dopamine responses in the PFC to external stimuli via dopamine D1 receptor signaling and attenuates cognitive deficit in MECP2 KO mice, a model mouse for Rett syndrome
2021/08 - BPNP BPNP
2020/05 - Ishibashi Foundation for the Promotion of Science Grant from the Ishibashi Foundation for the Promotion of Science
2018/02 - NPO法人レット症候群支援機構 2018年レット症候群研究費助成事業
2015/06 - Ishibashi Foundation for the Promotion of Science Grant from the Ishibashi Foundation for the Promotion of Science
2011/07 - Kurume University Mellenium Box Foundation for the Promotion of Science Grant from Kurume University Mellenium Box Foundation for the Promotion of Science
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Association Membership(s) (5):
International College of Neuropsychopharmacology (CINP)
, THE JAPANESE DENTAL SOCIETY OF ANESTHESIOLOGY
, JAPAN BRAIN SCIENCE SOCIETY
, THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY
, THE JAPANESE PHARMACOLOGICAL SOCIETY