Rchr
J-GLOBAL ID：201901004204899089
Update date: Nov. 15, 2024
Miura Yutaka
Miura Yutaka
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Research field (3)：
Biomaterials
, Environmental materials/recycling technology
, Chemical reaction and process system engineering
Research theme for competitive and other funds (11)：
2021 - 2027 国際共同研究による超高磁場MRIを用いた病理細胞診断の実現
2023 - 2026 薬剤徐放性ガンマ線架橋ハイドロゲルを用いた器質化促進能を有する人工血管の開発
2022 - 2026 Development of polymeric micelles based on innovative core-shell design for various therapeutic modalities
2021 - 2025 新規超分子医薬品によるオートファジー制御と悪性腫瘍治療法の開発
2016 - 2019 New treatment strategy for acute lower limb ischemia by using nano-micell
2016 - 2019 Development of novel supramolecular drug for the treatments of neointimal lesions and aortic aneurysm
2014 - 2017 Novel approach to acute limb ischemia with nano-DDS
2012 - 2016 Ligand-incorporated Polymeric Micelles for Advanced Therapeutic Strategies of Arteriosclerosis
2012 - 2015 Ligand-Linked Polymeric Micelles for Targeted Delivery of Platinum Anti-Cancer Drug into Malignant Tumor
2010 - 2012 Construction of vascular network in regenerative tissue by using angiogenic materials.
2010 - 2011 Development of novel DDS carriers incorporating water-soluble drug and potential for click release
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Papers (110)：
Masahiro Toyoda, Yutaka Miura, Motoaki Kobayashi, Masato Tsuda, Takahiro Nomoto, Yuto Honda, Hiroyuki Nakamura, Hiroyasu Takemoto, Nobuhiro Nishiyama. Synthesis and Optimization of Ethylenediamine-Based Zwitterion on Polymer Side Chain for Recognizing Narrow Tumorous pH Windows. Biomacromolecules. 2024
Keitaro Homma, Yutaka Miura, Motoaki Kobayashi, Wanphiwat Chintrakulchai, Masahiro Toyoda, Koichi Ogi, Junya Michinishi, Tomoyuki Ohtake, Yuto Honda, Takahiro Nomoto, et al. Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential. Science and technology of advanced materials. 2024. 25. 1. 2338785-2338785
Makoto Matsui, Yuka Kaihara, Yuto Honda, Nobuhiro Nishiyama, Yutaka Miura. Site-activatable targeting of macromolecular alendronate for accelerated fracture healing. Science and Technology of Advanced Materials. 2023. 24. 1
Shan Gao, Yutaka Miura, Akira Sumiyoshi, Satoshi Ohno, Keisuke Ogata, Takahiro Nomoto, Makoto Matsui, Yuto Honda, Minoru Suzuki, Megumi Iiyama, et al. Self-Folding Macromolecular Drug Carrier for Cancer Imaging and Therapy. Advanced Science. 2023
Xin Shen, Anjaneyulu Dirisala, Masahiro Toyoda, Yao Xiao, Haochen Guo, Yuto Honda, Takahiro Nomoto, Hiroyasu Takemoto, Yutaka Miura, Nobuhiro Nishiyama. pH-responsive polyzwitterion covered nanocarriers for DNA delivery. Journal of Controlled Release. 2023. 360. 928-939
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MISC (83)：
松平望, 松平望, 本田雄士, 本田雄士, 長尾周平, 長尾周平, 喜納宏昭, 野本貴大, 野本貴大, 三浦裕, et al. 腫瘍標的機能を備えた環状ペプチド搭載アデノ随伴ウイルス(AAV)三元系複合体の開発. 日本DDS学会学術集会プログラム予稿集. 2023. 39th
バトバヤル アヌダリ, 本田雄士, 野本貴大, 三浦裕, 西山伸宏. タンニン酸とフェニルボロン酸導入高分子から形成されるオボアルブミン内包三元系複合体の構築とがんワクチンアジュバントとしての応用. 日本DDS学会学術集会プログラム予稿集. 2023. 39th
小林基晃, 小林基晃, GHASEMIZADEH Aria, GHASEMIZADEH Aria, 豊田真広, 豊田真広, CHINTRAKULCHAI Wanphiwat, CHINTRAKULCHAI Wanphiwat, SUNG Yijung, SUNG Yijung, et al. ポリベタイン修飾脂質ナノ粒子を用いたpH変化をトリガーとする腫瘍選択的siRNA送達システムの開発. 日本DDS学会学術集会プログラム予稿集. 2023. 39th
持田祐希, CABRAL Horacio, 三浦裕, 長田健介, 西山伸宏, 片岡一則, 片岡一則. 白金制がん剤内包高分子ミセルの構造および機能を決定するヘリックス形成の重要性. 高分子学会予稿集(CD-ROM). 2018. 67. 1. ROMBUNNO.3H09
持田祐希, CABRAL Horacio, 三浦裕, 長田健介, 西山伸宏, 片岡一則, 片岡一則. PEG-ポリグルタミン酸の立体構造に着目した白金錯体超分子ミセルの粒径及び腫瘍標的性の制御. 高分子学会予稿集(CD-ROM). 2017. 66. 2. ROMBUNNO.1Q15
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Patents (8)：
エピルビシン複合化ブロック共重合体と、抗癌剤とを含むミセル、及び当該ミセルを含む癌又は耐性癌、転移癌の治療に適用可能な医薬組成物
高分子ナノ粒子複合体、及びそれを含むMRI造影用組成物
抗TissueFactorモノクローナル抗体
エピルビシン複合化ブロック共重合体と、抗癌剤とを含むミセル、及び当該ミセルを含む癌又は耐性癌、転移癌の治療に適用可能な医薬組成物
抗TissueFactorモノクローナル抗体
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