Kazuo Tatebayashi

タテバヤシカズオ | Kazuo Tatebayashi

Affiliation and department：
Job title：准教授

Research field (2)： Molecular biology , Functional biochemistry

Research keywords (8)：環境ストレス応答 , シグナル伝達 , HOG経路 , MAPキナーゼ , リン酸化 , 高浸透圧 , センサー , 酵母

Research theme for competitive and other funds (21)：

2021 - 2024 高浸透圧のキナーゼ反応増強作用による環境ストレス応答の新奇制御機構
2016 - 2019 Study on the osmo-sensing mechanism in yeast
2012 - 2016 Osmosensing mechanisms via oligomerization and dynamic interactions of the membrane proteins
2009 - 2010 Study on the mechanism to regulate the yeast osmo-regulatory MAPK pathway activation via phosphorylation and dephosphorylation
2008 - 2009 酵母ストレス応答MAPK経路におけるG蛋白質シグナル制御機構

2007 - 2008 Molecular osmo-sensing mechanism in the yeast HOG MAPK pathway

2006 - 2007 G蛋白質を介した酵母ストレス応答MAPK経路活性化機構の解明

2005 - 2006 Molecular functions of the Ssk1 osmo-regulator in the yeast HOG MAPK pathway

2002 - 2006 Regulatory mechanisms of the environmental stress-responsive MAP kinase signal pathway

2002 - 2006 Regulatory Mechanism of Stress-Responsive Signal Transduction Pathway in Human and Yeast Cells

2004 - 2004 ドッキング・サイトを介したストレス応答情報伝達経路の活性化と特異性維持の分子機構

2003 - 2004 酵母HOG経路のシグナル特異性決定に関わるPbs2MAPKKの足場機能の研究

2002 - 2002 ストレス応答キナーゼMTK1の活性制御機構とTGFβ情報伝達系における役割の解明

2002 - 2002 GADD45関連遺伝子とMTK1によるTh1免疫応答制御機構の解明と治療応用

2001 - 2002 環境ストレス応答MAPキナーゼ経路活性化機構の研究

1998 - 2002 Mechanisms of recombination mediated by DNA end-joining

2001 - 2001 TGFβによるストレス応答キナーゼMTK1の活性化機構と癌における制御異常の解明

2001 - 2001 遺伝子情報を利用した慢性関節リウマチの病態解析と分子診断法の開発

2000 - 2001 酵母cohesinの生物機能の新側面-姉妹染色分体間組換えとDNA修復への関与

1998 - 2001 Cross-talk between DNA repaif and recombination : two kinds of mechanisms that are mediated by DNA end-joining

1996 - 1996 分裂酵母rad21^+遺伝子産物の核構造維持と染色体分配に関する機能の解析

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Papers (29)：

Kazuo Tatebayashi, Haruo Saito. Two activating phosphorylation sites of Pbs2 MAP2K in the yeast HOG pathway are differentially dephosphorylated by four PP2C phosphatases Ptc1-Ptc4. The Journal of biological chemistry. 2023. 299. 4. 104569-104569
Nitika, Bo Zheng, Linhao Ruan, Jake T Kline, Siddhi Omkar, Jacek Sikora, Mara Texeira Torres, Yuhao Wang, Jade E Takakuwa, Romain Huguet, et al. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. PLoS biology. 2022. 20. 10. e3001839
Kazuo Tatebayashi, Katsuyoshi Yamamoto, Taichiro Tomida, Akiko Nishimura, Tomomi Takayama, Masaaki Oyama, Hiroko Kozuka-Hata, Satomi Adachi-Akahane, Yuji Tokunaga, Haruo Saito. Osmostress enhances activating phosphorylation of Hog1 MAP kinase by mono-phosphorylated Pbs2 MAP2K. The EMBO journal. 2020. 39. 5. e103444
Takayama Tomomi, Yamamoto Katsuyoshi, Saito Haruo, Tatebayashi Kazuo. Interaction between the transmembrane domains of Sho1 and Opy2 enhances the signaling efficiency of the Hog1 MAP kinase cascade in Saccharomyces cerevisiae. PLOS ONE. 2019. 14. 1
Akiko Nishimura, Katsuyoshi Yamamoto, Masaaki Oyama, Hiroko Kozuka-Hata, Haruo Saito, Kazuo Tatebayashi. Scaffold Protein Ahk1, Which Associates with Hkr1, Sho1, Ste11, and Pbs2, Inhibits Cross Talk Signaling from the Hkr1 Osmosensor to the Kss1 Mitogen-Activated Protein Kinase. MOLECULAR AND CELLULAR BIOLOGY. 2016. 36. 7. 1109-1123

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