Research field (5):
Tumor biology
, Immunology
, Cell biology
, Molecular biology
, Systems genomics
Research theme for competitive and other funds (3):
2020 - 2022 老化T細胞の機能解析およびその正常化方法の探索
2019 - 2021 T細胞老化を司るエピジェネティック制御機構の解明
2015 - 2018 EndMT制御機構の解明およびこれを基盤とした新規がん治療戦略の開発
Papers (9):
Yuji Sasaki, Yoshiki Higashijima, Jun-Ichi Suehiro, Takehito Sugasawa, Eri Oguri-Nakamura, Shigetomo Fukuhara, Nao Nagai, Yosuke Hirakawa, Youichiro Wada, Masaomi Nangaku, et al. Lysine demethylase 2B regulates angiogenesis via Jumonji C dependent suppression of angiogenic transcription factors. Biochemical and Biophysical Research Communications. 2022. 605. 16-23
Nagai N, Kudo Y, Aki D, Nakagawa H, Taniguchi K. Immunomodulation by Inflammation during Liver and Gastrointestinal Tumorigenesis and Aging. International Journal of Molecular Sciences. 2021. 22. 5. 2238-2238
Higashijima Y, Nagai N, Yamamoto M, Kitazawa T, Kawamura YK, Taguchi A, Nakada N, Nangaku M, Furukawa T, Aburatani H, et al. Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster. Communications biology. 2020. 3. 1. 725-725
Kondo T, Ando M, Nagai N, Tomisato W, Srirat T, Liu B, Mise-Omata S, Ikeda M, Chikuma S, Nishimasu H, et al. The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells. Cancer Research. 2020. 80. 3. 471-483