Ryuichi Ono

オノリュウイチ | Ryuichi Ono

Affiliation and department：

Research field (1)： Genomics

Research keywords (4)： retrotransposon , epigenetics , gene editing , exosome

Research theme for competitive and other funds (14)：

2022 - 2025 核酸ワクチンやゲノム編集遺伝子治療に係る安全性の評価と安全な運用に資する研究
2021 - 2024 The elucidation of regulatory mechanism of molecular network on RNA virus infection in diffuse- and intestinal-type gastric cancer
2018 - 2022 Development of cell-specific exosome isolation method by genetic modification
2015 - 2018 Development of a new treatment strategy to target mitochondrial chaperones in urothelial carcinoma
2014 - 2017 Functional analysis of Peg10, a paternally expressed imprinted gene

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Papers (51)：

Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, et al. Targeting of retrovirus-derivedRtl8a/8breduces social response and increases apathy-like behavior associated with GABRB2 reduction. 2024
Shihori Tanabe, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Hiroshi Yokozaki, Hiroki Sasaki, Edward Perkins. The Pathway Flow Starting From Chronic Reactive Oxygen Species Leading to Human Treatment-Resistant Gastric Cancer. 2024
TANABE Shihori, QUADER Sabina, ONO Ryuichi, CABRAL Horacio, AOYAGI Kazuhiko, PERKINS Edward J, YOKOZAKI Hiroshi, SASAKI Hiroki. The prediction of activation states of molecular pathways related to epithelial-mesenchymal transition and coronavirus. Annual Meeting of the Japanese Society of Toxicology. 2024. 51.1. O-34
TANABE Shihori, QUADER Sabina, ONO Ryuichi, CABRAL Horacio, AOYAGI Kazuhiko, PERKINS Edward J, YOKOZAKI Hiroshi, SASAKI Hiroki. Artificial Intelligence-Based Models to Predict the Activation State of Coronavirus Molecular Pathway Networks. Proceedings of the Annual Conference of JSAI. 2024. JSAI2024. 4Q3IS2d03-4Q3IS2d03
Ryuichi Ono, Makiko Kuwagata, Mie Naruse, Akihito Watanabe, Masao Takano, Takuro Hasegawa, Hiromasa Takashima, Yusuke Yoshioka, Takahiro Ochiya, Yoko Hirabayashi, et al. Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice. Fundamental Toxicological Sciences. 2024. 11. 1. 37-56

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MISC (63)：

Toshime Igarashi, Yukuto Yasuhiko, Ryuichi Ono, Yu Takahashi, Makiko Kuwagata, Satoshi Kitajima. Diverse on-target mutations in the genome-edited mice and their transmission to the next generation. Experimental Animals. 2024. 73. Supplement. S126-S126
田邊思帆里, カデールサビーナ, 小野竜一, カブラルオラシオ, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. がん幹細胞分子ネットワークにおける微小環境RNA制御. 日本再生医療学会総会(Web). 2023. 22nd
田邊思帆里, カデールサビーナ, 小野竜一, カブラルオラシオ, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. The master regulators of causal networks in intestinal- and diffuse-type gastric cancer. 日本癌学会学術総会抄録集(Web). 2023. 82nd
田邊思帆里, カデールサビーナ, 小野竜一, カブラルオラシオ, 青柳一彦, 広瀬明彦, パーキンスエドワード, 横崎宏, 佐々木博己. The development of AOP298 ”Increases in cellular reactive oxygen species and chronic reactive oxygen species leading to human treatment-resistant gastric cancer”. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
田邊思帆里, QUADER Sabina, 小野竜一, CABRAL Horacio, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. The relationship between coronavirus pathogenesis pathway and EIF2 signaling. 日本薬学会年会要旨集(Web). 2023. 143rd

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Education (1)：

2001 - 2004 東京工業大学大学院生命理工学研究科生物プロセス専攻博士課程

Professional career (1)：

博士(工学) (東京工業大学)

Work history (3)：

2016/11 - 現在 National Institute of Health Sciences
2014/12 - 2016/11 National Institute of Health Sciences
2005/11 - 2014/10 Tokyo Medical and Dental University Medical Research Institute

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