Research field (3):
Laboratory animal science
, Biological, health, and medical informatics
, Medical biochemistry
Research keywords (11):
Adeno associated virus
, mouse ES cell
, Linux
, R
, single cell RNA seq
, Python
, cytokine
, obesity
, metastasis
, fibrosis
, Liver
Research theme for competitive and other funds (9):
2022 - 2023 Modulation of Liver Cholesterol Homeostasis by Choline Supplementation During Fibrosis Resolution
2015 - 2019 Analysis of novel metabolic disorder regulating cytokine
2014 - 2017 Cellular interaction in liver inflammation and regeneration
2013 - 2016 A better understanding of liver environmental factors on hematogenous metastasis.
2010 - 2015 Studies on microenvironment that regulates hematopoietic cells
2010 - 2012 Cellular interaction in liver development and pathogenesis
2010 - 2011 Role of TRB family in liver disease
2005 - 2009 Mechanism of liver development
2007 - 2008 Analysis of molecular mechanisms governing tubular morphogenesisof hepatic bile ducts using three dimensional culture
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Papers (10):
Eiko SAIJOU, Yoshiko Kamiya, Katsunori Fujiki, Katsuhiko Shirahige, Ryuichiro Nakato. Modulation of Liver Cholesterol Homeostasis by Choline Supplementation During Fibrosis Resolution. Heliyon. 2024. 10. 17. e36727-e36727
Yasuhiro Nakano, Eiko Saijou, Tohru Itoh, Minoru Tanaka, Atsushi Miyajima, Taketomo Kido. Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state. Scientific Reports. 2024. 14. 1
Yuta Koui, Misao Himeno, Yusuke Mori, Yasuhiro Nakano, Eiko Saijou, Naoki Tanimizu, Yoshiko Kamiya, Hiroko Anzai, Natsuki Maeda, Luyao Wang, et al. Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling. Stem Cell Reports. 2021. 16. 12. 3050-3063
Eiko SAIJOU, Ryuichiro Nakato, Tohru Itoh. Analysis of cell-cell interactions using single-cell temporal data during recovery from liver fibrosis. 2023
Eiko SAIJOU. Modulation of Liver Cholesterol Homeostasis by Choline Supplementation During Fibrosis Resolution. 2023
Eiko SAIJOU. Analysis of cell-cell interactions using single-cell temporal data during recovery from liver fibrosis. 2022
Eiko SAIJOU. Comprehensive analysis of the liver fibrosis healing mechanism using single-cell analysis. 2021
Eiko SAIJOU, Tohru Itoh, Ryuichiro Nakato. Transcriptional dynamics of hepatic sinusoidal cells during fibrosis resolution. 2020