Koma Daisuke

コマダイスケ | Koma Daisuke

Affiliation and department：
Other affiliations (1)：

環境技術研究部研究主任

Homepage URL (1)： https://orist.jp/

Research field (1)： Applied microbiology

Research keywords (7)： Escherichia coli , Aromatic compound , Biorefinery , Fermentation , Chromosome engineering , Metabolic engineering , Synthetic biology

Research theme for competitive and other funds (7)：

2023 - 2026 高品質なバイオヒドロキシチロソールを再生可能な糖質原料から製造するための生産性と信頼性を兼ね備えた基盤技術の開発
2020 - 2023 Development of a novel fermentation process using N2-fixing Escherichia coli
2021 - 2021 広範な用途に利用できる無色透明なヒドロキシチロソールを安価に製造するための発酵生産基盤技術の高度化
2019 - 2020 Development of a novel method for hydroxytyrosol production by high-performance platform strain for aromatic compounds production
2015 - 2020 Development of a new method for chromosome-editting which is applicable to broad-ragne of bacteria

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Papers (27)：

Ning Shen, Yasuharu Satoh, Daisuke Koma, Hiroyuki Ohashi, Yasushi Ogasawara, Tohru Dairi. Optimization of tyrosol-producing pathway with tyrosine decarboxylase and tyramine oxidase in high-tyrosine-producing Escherichia coli. Journal of Bioscience and Bioengineering. 2024. 137. 2. 115-123
Yasuharu Satoh, Keita Fukui, Daisuke Koma, Ning Shen, Taek Soon Lee. Engineered Escherichia coli platforms for tyrosine-derivative production from phenylalanine using phenylalanine hydroxylase and tetrahydrobiopterin-regeneration system. Biotechnology for biofuels and bioproducts. 2023. 16. 1. 115-115
Daisuke Koma, Makoto Fujisawa, Hiroyuki Ohashi, Hayato Yamanaka, Kunihiko Moriyoshi, Eiji Nagamori, Takashi Ohmoto. Production of 3-Hydroxytyrosol from Glucose by Chromosomally Engineered Escherichia coli by Fed-Batch Cultivation in a Jar Fermenter. Journal of agricultural and food chemistry. 2023
Takehiro Fujita, Eri Nishi, Daisuke Koma, Masanobu Naito. Hydroxytyrosol: Bioinspired Nature-Based Adhesive Motif with Excellent Chemical Modifiability and Stability. ACS Applied Polymer Materials. 2023
Daisuke Koma, Takahiro Kishida, Eisuke Yoshida, Hiroyuki Ohashi, Hayato Yamanaka, Kunihiko Moriyoshi, Eiji Nagamori, Takashi Ohmoto. Chromosome Engineering To Generate Plasmid-Free Phenylalanine- and Tyrosine-Overproducing Escherichia coli Strains That Can Be Applied in the Generation of Aromatic-Compound-Producing Bacteria. Applied and environmental microbiology. 2020. 86. 14

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MISC (6)：

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Patents (16)：

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Books (1)：

生物工学よもやま話 -実験の基本原理から応用までー
2013

Lectures and oral presentations (84)：

芳香族化合物を生産する微生物の育種
(日本防菌防黴学会第46回年次大会 2019)
文化財修復に有用なポリビニルアルコール分解酵素の性質の検討
(日本防菌防黴学会第46回年次大会 2019)
ダイコン由来アラビノフラノシダーゼの特性解析と熱安定性の付与
(酵素・補酵素研究会 2019 2019)
T7 発現系を応用したプラスミドフリーで誘導剤が不要なフェニルアラニン高生産菌の開発
(日本生物工学会2018年度大会 2018)
種々の遺伝子改変の組み合わせが微生物燃料電池の出力に与える影響
(日本生物工学会2018年度大会 2018)

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Education (2)：

1998 - 2003 Ritsumeikan University Graduate School of Science and Engineering
1994 - 1998 Ritsumeikan University Faculty of Science and Engineering Department of Bioscience and Technology

Professional career (1)：

Science doctor

Work history (7)：

2019/04 - 現在 Osaka Institute of Technology Part-time instructor
2017/04 - 現在 Osaka Research Institute of Industrial Science and Technology Research Division of Environmental Technology Senior Research Scientist
2009/04 - 現在 Waseda University Research Institute for Science and Engineering Adjunct Researcher
2016/10 - 2017/03 Osaka Municipal Technical Research Institute Research Division of Environmental Technology Chief Research Scientist
2006/04 - 2016/09 Osaka Municipal Technical Research Institute Research Division of Environmental Technology Research Scientist

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Committee career (4)：

2015/04 - 現在文部科学省科学技術・学術政策研究所科学技術予測センター科学技術専門家ネットワーク・専門調査員
2016/06 - 2022/05 日本生物工学会関西支部若手企画委員会
2019/10 - 2020/03 NEDO 技術委員
2008/06 - 2013/05 日本生物工学会和文誌編集委員会

Awards (1)：

2016/05 - Osaka Industrial Research Association Industrial Technology Awards ponsored by Osaka Industrial Research Association Production of aromatic chemicals by metabolically engineered Escherichia coli

Association Membership(s) (4)：

American Society for Microbiology , Japan Society for Environmental Biotechnology , Japan Society for Bioscience, Biotechnology, and Agrochemistry , The Society for Biotechnology, Japan

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