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J-GLOBAL ID：202001007601004195   Update date: Nov. 20, 2024

Kono Yohei

コウノ ヨウヘイ | Kono Yohei
Affiliation and department：
Kanazawa University Nano Life Science Institute (WPI-NanoLSI)

About Kanazawa University Nano Life Science Institute (WPI-NanoLSI)


Job title： Postdoc
Homepage URL  (1)： http://researchgate.net/profile/yohei-kono-3
Research field  (4)： Cell biology ,  Molecular biology ,  Genomics ,  Applied molecular and cellular biology
Research keywords  (25)： Cell Nucleus ,  Nuclear Envelope ,  Nuclear Lamina ,  Lamin ,  Chromatin Structure ,  Live cell imaging ,  Progeria ,  Molecular and Genetic Medicine ,  Regenerative Medicine ,  Cell Engineering ,  Genetic Engineering ,  Viral Vector ,  shRNA ,  Cell Sheet ,  Cell Transplantation ,  Mesenchymal Stem Cell ,  iPS Cells ,  Differentiation ,  Fibrosis ,  Cancer Stem Cells ,  Drug Screening ,  Hepatitis ,  Non-Alcoholic Steato-Hepatitis ,  Nuclear Receptors ,  Biostatistics
Research theme for competitive and other funds  (2)：
  • 2020 - 2025 細胞シート工学を用いたラミノパチー疾患モデル構築と核ラミナ修復機構の解明
  • 2015 - 2018 Development of an early identification system for human hepatic differentiation tropic iPS cells focusing on glycosylation
Papers (15)：
  • Yohei Kono, Takeshi Shimi. Crosstalk between mitotic reassembly and repair of the nuclear envelope. Nucleus. 2024
  • Yohei Kono, Takeshi Shimi. Defective nuclear envelope repair in laminopathies. Journal of Japanese Biochemical Society. 2024. 96. 1. 101-105
  • Yohei Kono, Chan-Gi Pack, Takehiko Ichikawa, Arata Komatsubara, Stephen A. Adam, Keisuke Miyazawa, Loïc Rolas, Sussan Nourshargh, Ohad Medalia, Robert D. Goldman, et al. Delayed localization of A-type lamins to the rupture sites in Hutchinson-Gilford progeria syndrome. bioRxiv. 2023
  • Yohei Kono, Stephen A. Adam, Yuko Sato, Karen L. Reddy, Yixian Zheng, Ohad Medalia, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS. Journal of Cell Biology. 2022. 221. 12
  • Yohei Kono, Stephen A. Adam, Karen L. Reddy, Yixian Zheng, Ohad Medalia, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Nucleoplasmic Lamin C Rapidly Accumulates at Sites of Nuclear Envelope Rupture with BAF and cGAS. bioRxiv. 2022
ｍore...
MISC (71)：
  • Mohammad Mubarak Hosain, Yohei Kono, Keisuke Miyazawa, Takehiko Ichikawa, Takeshi Shimi, Takeshi Fukuma. Nanoendoscopy-AFM: A Novel Technique for Intracellular Imaging and Measurement of Mechanical Properties. 2024 Materials Research Society (MRS) Fall Meeting & Exhibit. 2024
  • 川瀬雅貴, 河野洋平, 市川壮彦, 木村宏, 福間剛士, 眞貝洋一, 志見剛. 細胞核の力学的特性はヘテロクロマチン構造によって強化される. 日本遺伝学会第96回大会. 2024. O3-4
  • Yohei Kono, Tatsuya Niwa, Yixian Zheng, Stephen A. Adam, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Establishment and analysis of immortalized mouse embryonic fibroblasts lacking all lamins. 日本細胞生物学会大会講演要旨集 76回. 2024. 3P20
  • Alexis S. Borowiak, T. Ichikawa, M. Itou, T. Shimi, Y. Kono, R. Nitta, T. Fukuma. Mechanical properties of hiPSC derived-cardiomyocytes: investigating beating and non-beating cell’s nucleus via Nanoendoscopy-AFM. 21st International Union of Pure and Applied Biophysics and 62nd Biophysics Society of Japan (IUPAB-BSJ 2024). 2024. 26P-252
  • Alexis S. Borowiak, K. Sivashanmugan, T. Ichikawa, E. Hirata, T. Shimi, Y. Kono, T. Fukuma. New approaches to directly image the surface of the nucleus at nanometer scale. European Materials Research Society (E-MRS) 2024 Spring Meeting. 2024. 12_1845
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Patents (24)：
  • Zellblatt mit fibrose-inhibierender wirkung
  • Fibrosis-inhibiting composition, cells producing same, and cell sheet comprising said cells
  • Cell sheet having fibrosis inhibitory action
  • 具有纖維化抑制作用之細胞層片
  • Inhibitory effect of low molecular weight compound on cancer and fibrosis
ｍore...
Books (2)：
  • 月刊薬事 2020年1月臨時増刊号 ここがキモ! いまはこうする肝疾患vs.薬物療法 肝機能評価&薬物性肝障害マネジメントに強くなる
    株式会社じほう 2020
  • 再生医療-日本再生医療学会雑誌
    メディカルレビュー社 2014 ISBN:9784779213830
Lectures and oral presentations  (2)：
  • Regenerative therapy for liver fibrosis using IC-2-engineered mesenchymal stem cell sheets
    (The 8th Meeting of the International Federation for Artificial Organs 2019)
  • Nuclear receptor gene expression during hepatic differentiation from human induced pluripotent stem cells with hepatic differentiation propensity
    (The 18th Takeda Science Foundation Symposium on Bioscience 2015)
Education (2)：
  • 2011 - 2020 Tottori University Graduate School of Medicine Institute of Regenerative Medicine and Biofunction
  • 2007 - 2011 Tottori University Faculty of Medicine School of Life Science
Work history (8)：
  • 2024/04 - 現在 Kanazawa University Nano Life Science Institute (WPI-NanoLSI) Postdoc
  • 2023/08 - 2024/03 Kanazawa University Institute of Science and Engineering Faculty of Frontier Engineering Postdoc
  • 2020/01 - 2023/03 Tokyo Institute of Technology Cell Biology Center, Institute of Innovative Research Research Staff
  • 2018/11 - 2019/12 Tottori University Department of Genetic Medicine and Regenerative Therapeutics, Graduate School of Medicine Assistant Professor (without tenure)
  • 2017/04 - 2018/10 KanonCure, Inc. Startup company from Tottori University Representative director and Reseacher (self-employment)
Show all
Awards (3)：
  • 2024/02 - Sartorius Japan Winner at 13th Pipetting Contest Produced by Sartorius Japan, Record:0.05%
  • 2022/06 - Japan Society for Cell Biology Young Scientist Award for Presentation 2022 Nucleoplasmic Lamin C Rapidly Accumulates at Sites of Nuclear Envelope Rupture
  • 2010/02 - Japan Association of Biotechnology Education Top Scorers in the 15th Biotechnologist Certification [Upper Grade]
Association Membership(s) (5)：
Japan Society for Cell Biology ,  The Molecular Biology Society of Japan ,  The Japanese Society for Regenerative Medicine ,  The Japan Society of Hepatology ,  The Japanese Society for the Research of Hepatic Cells
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