Kuwagata Makiko

クワガタマキコ | Kuwagata Makiko

Affiliation and department：
Job title：室長
Research theme for competitive and other funds (7)：

2017 - 2020 Elucidation of the onset mechanism of osteoporosis and osteoarthritis caused by stress on mesenchymal stem cells
2017 - 2020 Multi-omics approach unraveling neonatal mouse brain for DOHaD
2015 - 2019 Mechanism of vulnerability formation by nutritional environment change at developmental stage.
2016 - 2019 発生毒性試験における胎児形態異常に関するデータ収集と骨格変異の毒性学的意義に関する研究:フルシトシン誘発性過剰肋骨の発現機序からの考察
2012 - 2015 later

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Papers (41)：

Ryuichi Ono, Makiko Kuwagata, Mie Naruse, Akihito Watanabe, Masao Takano, Takuro Hasegawa, Hiromasa Takashima, Yusuke Yoshioka, Takahiro Ochiya, Yoko Hirabayashi, et al. Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice. Fundamental Toxicological Sciences. 2024. 11. 1. 37-56
五十嵐智女, 松村万里, 小川いずみ, 矢川千織, 早川孝彦, 越智美代子, 齊藤洋克, 西村拓也, 桑形麻樹子, 北嶋聡. フードテックを応用した細胞培養食品を含む「新規食品」の安全性確保に関する諸外国の制度比較と最近の動向. The Journal of Toxicological Sciences. 2023. 48. Suppl. S148-S148
Makiko Kuwagata, Masaru Tsuboi, Toshime Igarashi, Mariko Tsurumoto, Takuya Nishimura, Yuhji Taquahashi, Satoshi Kitajima. A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats. Fundamental Toxicological Sciences. 2023. 10. 2. 69-82
Makiko Kuwagata, Masaru Tsuboi, Toshime Igarashi, Mariko Tsurumoto, Takuya Nishimura, Yuhji Taquahashi, Satoshi Kitajima. A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats. Fundamental Toxicological Sciences. 2023. 10. 2. 59-68
Yuhji Taquahashi, Hirokatsu Saito, Makiko Kuwagata, Satoshi Kitajima. Development of an inhalation exposure system of a pressurized metered-dose inhaler (pMDI) formulation for small experimental animals. Fundamental Toxicological Sciences. 2021. 8. 6. 169-175

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MISC (10)：

Toshime Igarashi, Yukuto Yasuhiko, Ryuichi Ono, Yu Takahashi, Makiko Kuwagata, Satoshi Kitajima. Diverse on-target mutations in the genome-edited mice and their transmission to the next generation. Experimental Animals. 2024. 73. Supplement. S126-S126
Toshime Igarashi, Mari Matsumura, Izumi Ogawa, Chiori Yakawa, Takahiko Hayakawa, Miyoko Ochi, Hirokatsu Saito, Makiko Kuwagata, Satoshi Kitajima. Comparative study of regulatory systems in other countries to ensure the safety of “new foods”. Journal of Toxicological Sciences. 2022. 47. Supplement. P-125
Toshime Igarashi, Sakiko Fujii, Mariko Tsurumoto, Yuji Taquahashi, Satoshi Kitajima, Makiko Kuwagata. Uterotrophic bioassay of 4,4'-(1,3-dimethylbutylidene) diphenol, a bisphenol analog, using ovariectomized mice by subcutaneous and oral administration. Journal of Toxicological Sciences. 2022. 47. Supplement. P-246
Philip Marx-Stoelting, Marize de L.M. Solano, Hiroaki Aoyama, Ralf H. Adams, Anna Bal-Price, Jochen Buschmann, Ibrahim Chahoud, Ruth Clark, Tian Fang, Michio Fujiwara, et al. 25th anniversary of the Berlin workshop on developmental toxicology: DevTox database update, challenges in risk assessment of developmental neurotoxicity and alternative methodologies in bone development and growth. Reproductive Toxicology. 2021. 100. 155-162
Toshime Igarashi, Yukuto Yasuhiko, Ryuichi Ono, Erika Tachihara, Miki Uchiyama, Atsuya Takagi, Yu Takahashi, Makiko Kuwagata, Satoshi Kitajima. Germline-transmission in the knock-in mice of N0 generation with diverse and unintended on-target mutations induced by CRISPR/Cas9-mediated genome editing. 2021. 46. Supplement. P-91

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Lectures and oral presentations (1)：

Research on the mechanism of thoracolumbar supernumerary rib development after birth using CT scanning
(2018)

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