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J-GLOBAL ID：202101002051967344   Update date: Aug. 01, 2024

Zhang Ming-Rong

チョウ メイエイ | Zhang Ming-Rong
Affiliation and department：
National Institutes for Quantum and Radiological Science and Technology Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science

About National Institutes for Quantum and Radiological Science and Technology Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science


Job title： Director
Research field  (3)： Tumor diagnostics and therapeutics ,  Pharmaceuticals - chemistry and drug development ,  Radiology
Research keywords  (6)： Radiochemistry ,  Radiopharmaceutical Chemistry ,  Molecular Imaging ,  Theranostics ,  Targeted Radionuclide Therapy (TRT) ,  PET/SPECT
Research theme for competitive and other funds  (22)：
  • 2023 - 2028 Comprehensive basic research for the development of therapies targeting senescent cells and their clinical applications
  • 2024 - 2027 環状ヌクレオチドホスホジエステラーゼ7を標的とするPETプローブの開発
  • 2023 - 2027 Development of New Positron Emission Tomography Probes for Imaging PDE7
  • 2022 - 2025 Development of new radiotherapeutic drugs against metabolism of refractory bile duct cancer
  • 2021 - 2025 Stapled peptide-based radiotheranostics for intracellular protein-protein interactions targeted cancer imaging and therapy
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Papers (460)：
  • Siqi Zhang, Xiaohui Ma, Jiang Wu, Jieting Shen, Yuntao Shi, Xingkai Wang, Lin Xie, Xiaona Sun, Yuxuan Wu, Hao Tian, et al. Enhanced radiotheranostic targeting of integrin α5β1 with PEGylation-enabled peptide multidisplay platform (PEGibody): A strategy for prolonged tumor retention with fast blood clearance. Acta Pharmaceutica Sinica B. 2024
  • Zhongshan He, Wei Chen, Kuan Hu, Yaoyao Luo, Wanqin Zeng, Xi He, Tingting Li, Jiang Ouyang, Yongjiang Li, Lin Xie, et al. Resolvin D1 delivery to lesional macrophages using antioxidative black phosphorus nanosheets for atherosclerosis treatment. Nature Nanotechnology. 2024
  • Hideki Ishii, Katsuyuki Minegishi, Kotaro Nagatsu, Nobuki Nengaki, Ming-Rong Zhang. Novel synthesis of 11C-labeled imidazolines via Pd(0)-mediated 11C-carbomethoxylation using [11C]CO and arylborons. Journal of labelled compounds & radiopharmaceuticals. 2024. 67. 6. 227-234
  • Hironobu Endo, Maiko Ono, Yuhei Takado, Kiwamu Matsuoka, Manami Takahashi, Kenji Tagai, Yuko Kataoka, Kosei Hirata, Keisuke Takahata, Chie Seki, et al. Imaging α-synuclein pathologies in animal models and patients with Parkinson's and related diseases. Neuron. 2024
  • Kosei Hirata, Kiwamu Matsuoka, Kenji Tagai, Hironobu Endo, Harutsugu Tatebe, Maiko Ono, Naomi Kokubo, Yuko Kataoka, Asaka Oyama, Hitoshi Shinotoh, et al. In Vivo Assessment of Astrocyte Reactivity in Patients with Progressive Supranuclear Palsy. Annals of neurology. 2024
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MISC (103)：
  • 謝琳, 破入正行, 張一鼎, 藤永雅之, 峯岸克行, 大久保崇之, 永津弘太郎, 下川卓志, 足助一真, 張明栄. mGluR1陽性ヒト癌に対する211At-AITMによる標的アイソトープ治療の検証. 核医学(Web). 2023. 60. Supplement
  • 吉井幸恵, 檜原扶紀子, 五十嵐千佳, 張明栄, 大島聡人, 佐藤秀光, 成田善孝, 栗原宏明, 山本哲哉, 東達也, et al. 低酸素標的放射性薬剤64Cu-ATSMを用いた高悪性度神経膠腫に対する局所治療. 核医学(Web). 2023. 60. Supplement
  • 山崎友照, 藤永雅之, 大久保崇之, 大久保崇之, 下條雅文, 小野麻衣子, 永井裕司, 小川政直, 念垣信樹, 小川政直, et al. 新規レポーター遺伝子イメージング剤[18F]FE-TMP-d4の小動物を用いた有効性評価. 核医学(Web). 2023. 60. Supplement
  • 矢内凛, 南久松丈晴, 下條雅文, 洲崎悦生, 三谷智樹, 上田泰己, 張明栄, 佐原成彦, 樋口真人. 透明化とPETを用いた新規タウオパチーモデルマウスの全脳3Dイメージング. Dementia Japan. 2023. 37. 4
  • 河村和紀, 森若菜, 栗原雄祐, 小川政直, 塚越海渡, 大久保崇之, 念垣信樹, 藤永雅之, 橋本裕輝, 張明栄, et al. 臨床利用へ向けた簡易的1ポット[18F]FMeNER-D2製造法の確立. 核医学(Web). 2023. 60. Supplement
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Patents (26)：
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Work history (5)：
  • 2016/04 - 現在 National Institutes for Quantum and Radiological Science and Technology Department of Advanced Nuclear Medicine Sciences Director
  • 2012/04 - 2016/03 National Institute of Radiological Sciences
  • 2007/10 - 2012/03 放射線医学総合研究所 分子認識研究グループ標識技術チーム チームリーダー
  • 2000/03 - 2007/09 放射線医学総合研究所 研究員
  • 1998/04 - 2000/03 科学技術振興事業団 博士研究員
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