Imai Yumiko

イマイユミコ | Imai Yumiko

Affiliation and department：
Job title： Project Leader
Other affiliations (1)：

Osaka University Institute for Protein Research Specially Appointed Professor

Research theme for competitive and other funds (16)：

2020 - 2024 Multifaceted pathophysiologic evaluation of sepsis targeting the intestinal microflora and development of novel therapeutic strategies
2020 - 2023 Analysis of Pathophysiology in ICU acquired weakness using proteomics
2020 - 2023 Mechanistic insights into spatio-temporal regulation of RNA in cardio-metabolic disease
2017 - 2022 Identification of higher-order-epigenetic modification machineries and development of potential novel therapeutics in severe virus infection
2017 - 2020 重症ウイルス感染症における高次エピゲノム作動原理の解明

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Papers (50)：

Tomokazu Yamaguchi, Ryo Ozawa, Takafumi Minato, Midori Hoshizaki, Yutaro Kammura, Kazuma Okawara, Yousef A Khalil, Masafumi Nakamura, Ken Yamaura, Masayuki Fukuda, et al. Haploinsufficiency of Cnot3 Aggravates Acid-Induced Acute Lung Injury Likely Through Transcriptional and Post-Transcriptional Upregulation of Pro-Inflammatory Genes. Journal of inflammation research. 2024. 17. 5415-5425
Jianbo An, Yushi Nagaki, Satoru Motoyama, Yuta Kuze, Midori Hoshizaki, Kohei Kemuriyama, Tomokazu Yamaguchi, Takashi Ebihara, Yoshihiro Minamiya, Yutaka Suzuki, et al. Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression. Oncogene. 2022. 41. 50. 5319-5330
Takafumi Minato, Tomokazu Yamaguchi, Midori Hoshizaki, Satoru Nirasawa, Jianbo An, Saori Takahashi, Josef M Penninger, Yumiko Imai, Keiji Kuba. ACE2-like enzyme B38-CAP suppresses abdominal sepsis and severe acute lung injury. PloS one. 2022. 17. 7. e0270920
Tomokazu Yamaguchi, Midori Hoshizaki, Takafumi Minato, Satoru Nirasawa, Masamitsu Asaka, Mayumi Niiyama, Jianbo An, Daichi Utsumi, Satoshi Nagata, Haruhiko Kamada, et al. Therapeutic effects of angiotensin converting enzyme 2 (ACE2) enzyme activity on acute lung injury in COVID-19. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 2-O
Tomokazu Yamaguchi, Midori Hoshizaki, Takafumi Minato, Satoru Nirasawa, Masamitsu N Asaka, Mayumi Niiyama, Masaki Imai, Akihiko Uda, Jasper Fuk-Woo Chan, Saori Takahashi, et al. ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury. Nature communications. 2021. 12. 1. 6791-6791

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MISC (17)：

Akihiko Nakaya, Seiki Fujiwara, Misako Higashiya, Ayumi Kadowaki, Keiji Kuba, Yumiko Imai. Analysis of the host epigenetic responses to influenza virus infection - role of histone methylations in the pathogenesis of influenza -. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 85P-85P
Takashi Suzuki, Keiji Kuba, Teruki Sato, Ayumi Kadowaki, Yumiko Imai. Analysis for the role of CNOT3-mediated mRNA metabolism in cardiac homeostasis. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 196P-196P
Teruki Sato, Keiji Kuba, Takashi Suzuki, Ayumi Kadowaki, Yumiko Imai. A network of Apelin and ACE2 regulates cardiac contractility in failing hearts. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 106P-106P
Yumiko Imai, Keiji Kuba. Novel approaches to the pathogenesis of ARDS. Respiration and Circulation. 2013. 61. 7. 650-655
Akihiko Ichikawa, Masayuki Morita, Keiji Kuba, Yumiko Imai. In vivo imaging of damage associated molecular patterns (DAMPs) DNA in mouse lungs with ARDS. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 217P-217P

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