Research field (7)：
Nutrition and health science
, Tumor diagnostics and therapeutics
, Tumor biology
, Pharmaceuticals - chemistry and drug development
, Hematology and oncology
, Laboratory animal science
, Food sciences
Research keywords (13)：
酸化ストレス
, APC gene
, colorectal carcinogenesis
, Cancer Genome Test
, Drug Development
, cancer supportive care
, bone metastasis
, functional food
, chemoprevention
, mouse model
, tumor suppressor gene
, curcumin
, Cancer
Research theme for competitive and other funds (18)：
2020 - 2023 Cancer chemoprevention by using diarylpentanoid analog of curcumin as a functional food
2014 - 2017 Development of a new treatment strategy using TDM for next generation anticancer drug
2013 - 2016 Pharmacological potential of curcumin analog targeting KSRP, a regulator of miRNA
2010 - 2012 Development of a new cancer chemotherapy by using curcumin analogs
2005 - 2009 Development of functional assays for tumor-related genes
2004 - 2005 Development of a nobel strategy for chemoprevention of colorectal carcinogenesis by using newly synthesized organic compounds derived from natural dietary constituents
2000 - 2004 がん関連遺伝子変異の検出および機能評価法の開発
2002 - 2003 Development of p53-associated molecular devices for diagnosis and treatment of gastrointestinal cancer
2001 - 2002 大腸癌発がんをコントロールする新しい標的分子の同定と発がん予防・治療薬開発
1999 - 2001 Establishment of a new strategy for colorectal cancer gene therapy by controlling Wnt-signal molecules
1999 - 2001 Functional mapping of missens mutations in hMLH1 gene
1998 - 2000 Inactivation model of human Adenomatous Polyposis Coli gene by using budding yeast in vivo.
1996 - 1999 ジーンターゲティングによるヒト発癌機構の解析
1996 - 1997 Joint study on the DNA mismatch repair system : Functional analysis of the DNA mismatch repair genes using Saccharomyces cerevisiae.
1995 - 1997 Establishment of novel conditional gene targeting methods using Cre-loxP system
1996 - 1996 ジーンターゲティングによるPEBP遺伝子ファミリーの機能の解析
1995 - 1995 マウス神経系初期発生におけるPOU転写調節因子の役割の解析
1994 - 1994 マウス神経系初期発生におけるPOU転写調節因子の役割の解析
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Papers (152)：
Kazuma Fujita, Daiki Taguchi, Koji Fukuda, Taichi Yoshida, Kazuhiro Shimazu, Hanae Shinozaki, Hiroyuki Shibata, Masatomo Miura. Association between albumin-bilirubin grade and plasma trough concentrations of regorafenib and its metabolites M-2 and M-5 at steady-state in Japanese patients. Investigational new drugs. 2024. 42. 3. 252-260
Kenji Matsuda, Kazuhiro Shimazu, Hanae Shinozaki, Koji Fukuda, Taichi Yoshida, Daiki Taguchi, Kyoko Nomura, Hiroyuki Shibata. Recent trends in bone metastasis treatments: A historical comparison using the new Katagiri score system. World journal of clinical cases. 2024. 12. 15. 2499-2505
Katsunori Iijima, Kenta Watanabe, Yosuke Shimodaira, Shigeto Koizumi, Sho Fukuda, Tatsuki Yoshida, Ryo Ookubo, Tamotsu Matsuhashi, Mario Jin, Masahito Miura, et al. A Final Report on the Real Impact of the COVID-19 Pandemic on the Diagnosis of Gastrointestinal Cancer in Akita Prefecture, Japan in 2022. The Tohoku journal of experimental medicine. 2024
柴田 浩行. 骨転移診療ガイドライン改訂のポイント-Revised points of the comprehensive guideline for diagnosis and treatment of bone metastasis (version 2)-特集 整形外科とがん診療 : 骨軟部腫瘍と骨転移アップデート. Precision medicine = プレシジョンメディシン / 「Precision medicine」編集委員会 編. 2024. 7. 4. 270-273
Juri Yamada, Koji Fukuda, Tae Sugawara, Kenichi Makino, Kazuhiro Shimazu, Taichi Yoshida, Daiki Taguchi, Hanae Shinozaki, Yukihiro Terada, Hiroshi Nanjo, et al. A case of hereditary breast and ovarian cancer syndrome of initially presented as cancer of unknown primary with lymph node metastases unveiled by genetic analysis. International cancer conference journal. 2024. 13. 2. 139-143
