Rchr
J-GLOBAL ID：202201016736870090   Update date: Nov. 05, 2024

Tanaka Yosuke

タナカ ヨウスケ | Tanaka Yosuke
Affiliation and department：
The University of Tokyo The Institute of Medical Science

About The University of Tokyo The Institute of Medical Science


Research field  (3)： Developmental biology ,  Hematology and oncology ,  Hematology and oncology
Research keywords  (5)： Hematopoietic stem cells ,  Developmental hematology ,  Leukemic stem cell ,  Cell fate decision ,  Cell cycle
Research theme for competitive and other funds  (6)：
  • 2023 - 2026 クロマチン動態の差異に起因する造血幹細胞のサイトカイン応答パラドックス
  • 2021 - 2023 Identification of true HSC niche by visualization of contact and proximity between HSCs and various niche cells
  • 2019 - 2021 CRISPR/Cas9-mediated base-editing enables a chain reaction through sequential repair of sgRNA scaffold mutations
  • 2017 - 2019 Maintenance of multipotency of hematopoietic stem cells and distribution of midbody
  • 2015 - 2017 Multipotency of HSCs and midbody movement
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Papers (41)：
  • Yosuke Tanaka, Yasushi Kubota, Ivo Lieberam, Takaharu Kimura, Jillian Barlow, Josh Bramley, Chiaki Sakuma, Takashi Shibata, Nakagawa Masataka, Yasunori Kurosawa, et al. Prospective isolation of mouse and human hematopoietic stem cells using Plexin domain containing 2. 2024
  • Wenjuan Ma, Shah Adil Ishtiyaq Ahmad, Michihiro Hashimoto, Ahad Khalilnezhad, Miho Kataoka, Yuichiro Arima, Yosuke Tanaka, Shigeru Yanagi, Terumasa Umemoto, Toshio Suda. MITOL deficiency triggers hematopoietic stem cell apoptosis via ER stress response. The EMBO Journal. 2024
  • Wenjuan Ma, Yuichiro Arima, Terumasa Umemoto, Tomomasa Yokomizo, Yuqing Xu, Kenichi Miharada, Yosuke Tanaka, Toshio Suda. Metabolic regulation in erythroid differentiation by systemic ketogenesis in fasted mice. Experimental hematology. 2023
  • Tomohiro Yabushita, Takumi Chinen, Atsuya Nishiyama, Shuhei Asada, Ruka Shimura, Tomoya Isobe, Keita Yamamoto, Naru Sato, Yutaka Enomoto, Yosuke Tanaka, et al. Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment. Cell reports. 2023. 42. 9. 113098-113098
  • Hans Jiro Becker, Reiko Ishida, Adam C Wilkinson, Takaharu Kimura, Michelle Sue Jann Lee, Cevayir Coban, Yasunori Ota, Yosuke Tanaka, Meike Roskamp, Tsubasa Sano, et al. Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion. Cell stem cell. 2023. 30. 7. 987-1000
ｍore...
MISC (3)：
  • 久保田 寧, 田中 洋介, Ivo Lieberam, 丸山 俊昭, 芥 照夫, 木村 晋也, 北村 俊雄. 高純度の造血幹細胞分離を可能とするマウス・ヒトに共通するマーカー、Plxdc2の同定. 日本輸血細胞治療学会誌. 2022. 68. 2. 319-319
  • Yasutaka Hayashi, Kimihito Cojin Kawabata, Yosuke Tanaka, Yasufumi Uehara, Shigeru Kiryu, Yasunori Ota, Yusuke Yoshioka, Yo Mabuchi, Tatsuki Sugiyama, Keiko Mikami, et al. Impaired Osteoblastic Differentiation of MSCs Suppresses Normal Hematopoiesis in MDS. BLOOD. 2020. 136
  • Kimihito Cojin Kawabata, Yasutaka Hayashi, Daichi Inoue, Hiroki Mizuno, Jiro Kitaura, Yosuke Tanaka, Susumu Goyama, Yuka Harada, Hironori Harada, Hiroyuki Aburatani, et al. HIGHER EXPRESSION OF ATP-BINDING CASSETTE TRANSPORTER G2 (ABCG2) IS SPECIFIC TO ADVANCED MDS AND PROMOTES INEFFICIENT HEMATOPIESIS VIA CONVERSIONS OF TUMOR MICROENVIRONMENTS IN MOUSE BONE MARROW TRANSPLANTATION MODEL. EXPERIMENTAL HEMATOLOGY. 2016. 44. 9. S110-S110
Education (4)：
  • 2004 - 2008 Department of molecular medicine, Graduate School of Medicine Kyoto University.
  • 2002 - 2004 Division of Medicine Graduate School of Medicine Osaka University
  • 1997 - 2002 Faculty of Agriculture, Kyoto University
  • - 1997 巣鴨中学校・高等学校
Work history (7)：
  • 2024/04 - 現在 The University of Tokyo The Institute of Medical Science Center for Experimental Medicine and Systems Biology
  • 2022/04 - 2024/03 熊本大学 International Research Center for Medical Sciences
  • 2015/04 - 2022/03 東京大学 The Institute of Medical Science Division of Stem Cell Signaling
  • 2013/04 - 2015/03 University of Cambridge Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute Department of Haematology
  • 2010/04 - 2013/03 RIKEN Center for Developmental Biology Laboratory for Stem Cell Biology
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