Research field (6):
Clinical pharmacy
, Pharmaceuticals - chemistry and drug development
, Pharmacology
, Pharmaceuticals - health and biochemistry
, Biomaterials
, Biomedical engineering
Research keywords (8):
蛋白質工学
, プロテオミクス
, 薬物送達法
, 毒性学
, NanoTox
, Drug Therapeutics
, Biopharmaceutics
, Drug Delivery System
Research theme for competitive and other funds (39):
2021 - 2024 マイクロプラスチックのリスク評価基盤の構築
2014 - 2019 Development of a new diagnostic method for heart failure in collaboration with drug engineers
2015 - 2017 Challenge to develop safety and effective nano-carriers for contributing to creation of mucosal vaccine
2013 - 2015 Approach to develop a dynamics control technology of nanomaterial for oral nano-vaccine carrier
2011 - 2012 Development of transcutaneous vaccine with efficacy and safety for the overcoming infectious diseases
2009 - 2012 The creation and safety assessment of cytokine adjuvant and nano-carrier for mucosal vaccine
2008 - 2009 An organelle targeting system as a next generation technology for drug development
1995 - 1996 Development of fusogenic liposomes which can deliver any substances into the cells through membrane fusion
1995 - 1996 Preparation of aniti-tumor tissue endothelium antibodies and its application of cancer-missle therapy
ナノマテリアルの安全性研究
抗体プロテオミクスによる創薬バイオマーカー探索
医薬価値に優れた機能性人工蛋白質の創出
Creation of functional muteins
Study on drug delivery system for vaccine
Development of Targeting Therapy for Cancer
Molecular Design of Multi-Functional Hybrid Drug
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Papers (259):
Yudai Ikuno, Hirofumi Tsujino, Yuya Haga, Sota Manabe, Wakaba Idehara, Mii Hokaku, Haruyasu Asahara, Kazuma Higashisaka, Yasuo Tsutsumi. Polyethylene, whose surface has been modified by UV irradiation, induces cytotoxicity: A comparison with microplastics found in beaches. Ecotoxicology and environmental safety. 2024. 277. 116346-116346
Hiroto Konishi, Yuya Haga, Moe Okumura, Hirofumi Tsujino, Kazuma Higashisaka, Yasuo Tsutsumi. Coculture with macrophages alters ferroptosis susceptibility of triple-negative cancer cells. Cell Death Discovery. 2024. 10. 1
Health effects of fine particle exposure on vulnerable generations. BIO Clinica. 2022. 37. 1. 59-63
松下俊介, 橘敬祐, 日下部哲也, 日下部哲也, 堤康央, 近藤昌夫. Regulatory Considerations of Conditional Approval for Balancing Pre-market and Post-market Evaluations to Achieve Early Patient Access to Medical Products in Japan. レギュラトリーサイエンス学会誌. 2021. 11. 2
庄真喜子, 橘敬祐, 原田和生, 平田收正, 堤康央, 國澤純, 國澤純, 國澤純, 國澤純, 國澤純, et al. Current situation and challenges of a regulatory concept of pharmacokinetics focusing on microbiome. 腸内細菌学雑誌. 2021. 35. 2