J-GLOBAL ID:200901001553249540   Update date: Oct. 20, 2020

Kodama Tetsuya

コダマ テツヤ | Kodama Tetsuya
Affiliation and department:
Job title: Professor
Other affiliations (1):
  • Tohoku University  Grad School Eng, Grad School Med, Inst Fluid Sci, Grad School Dent
Homepage URL  (2): http://db.tohoku.ac.jp/whois/detail/0439e1975b16d53cc7fb7b6209c8aafb.htmlhttp://db.tohoku.ac.jp/whois/e_detail/0439e1975b16d53cc7fb7b6209c8aafb.html
Research field  (3): Biomaterials ,  Biomedical engineering ,  Medical systems
Research keywords  (7): ultrasound ,  nanobubbles ,  DDS ,  treatment ,  diagnosis ,  cancer ,  lymphatic metastasis
Research theme for competitive and other funds  (72):
  • 2019 - 2022 リンパ節内圧測定によるリンパ節転移超早期診断とリンパ行性薬剤導入システム治療
  • 2018 - 2020 超微小転移リンパ節の精密診断と新化学療法に関する総合的研究
  • 2017 - 2019 Low operation by siRNA with angiogenetic inductive action and modal nano drug delivery, initiation of hurt repairing procedure
  • 2017 - 2019 Therapeutic system for metastatic lymph nodes at early stages
  • 2016 - 2019 ミクロ・ナノ熱工学によるがんの早期診断と低侵襲治療
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Papers (132):
  • Kato S, Takeda K, Sukhbaatar A, Sakamoto M, Mori S, Shiga K, Kodama T. Intranodal pressure of a metastatic lymph node reflects the response to lymphatic drug delivery system. Cancer Sci. 2020
  • Kato S, Shirai Y, Motozono C, Kanzaki H, Mori S, Kodama T. In vivo delivery of an exogenous molecule into murine T lymphocytes using a lymphatic drug delivery system combined with sonoporation. Biochem Biophys Res Commun. 2020
  • Sukhbaatar A, Sakamoto M, Mori S, Kodama T. Analysis of tumor vascularization in a mouse model of metastatic lung cancer. Scientific Reports. 2019. 9. 1. 16029
  • Kato S, Shirai Y, Sakamoto M, Mori S, Kodama T. Use of a lymphatic drug delivery system and sonoporation to target malignant metastatic breast cancer cells proliferating in the marginal sinuses. Scientific Reports. 2019. 9. 1. 13242
  • Takuya Izumiyama, Yu Mori, Shiro Mori, Naoko Mori, Tetsuya Kodama, Eiji Itoi. The effect of anti-IL-6 receptor antibody for the treatment of McH-lpr/lpr-RA1 mice that spontaneously developed destructive arthritis and enthesitis. BMC Musculoskeletal Disorders. 2019. 20. 1
MISC (51):
  • KODAMA Tetsuya. Lymph nodes targeted in novel cancer therapy. Research Outreach. 2018. 105. 22-25
  • Horie S, Kodama T, Sato Y. Application of a drug delivery system using ultrasound and nano/microbubbles for anti-angiogenic therapy. Radiation Biology Research Communications. 2017. 52. 1. 14-23
  • 小嶋郁穂, 阪本真弥, 飯久保正弘, 小川武則, 渡邉みか, 大田英揮, 村田隆紀, 森士朗, 小玉哲也, 笹野高嗣. 3テスラblack-blood MR imagingが口腔癌患者の頸部リンパ節転移診断に有用であった2症例. 歯科放射線. 2016. 56. 51
  • Naoko Mori, Shunji Mugikura, Chiaki Takasawa, Minoru Miyashita, Akiko Shimauchi, Hideki Ota, Takanori Ishida, Atsuko Kasajima, Kei Takase, Tetsuya Kodama, et al. Peritumoral apparent diffusion coefficients for prediction of lymphovascular invasion in clinically node-negative invasive breast cancer (vol 26, pg 331, 2016). EUROPEAN RADIOLOGY. 2016. 26. 2. 340-341
  • 森 菜緒子, 嶋内 亜希子, 宮下 穣, 石田 孝宣, 伊藤 康一, 工藤 由美子, 三木 美香, 小玉 哲也, 高瀬 圭. 今、イメージングで見えているものは何か? 医療現場での未来の応用を考える 造影超音波定量解析による乳癌早期リンパ節転移診断. 日本癌学会総会記事. 2015. 74回. S4-6
Patents (8):
Books (1):
  • Recent technology of microbubbles vol.2
    NTS 2014 ISBN:9784860434076
Lectures and oral presentations  (473):
  • Therapeutic dependence of osmotic pressure when administering anticancer drugs using a lymphatic drug delivery system
    (The 79th Annual Meeting of the Japanese Cancer Association 2020)
  • Quantitative analysis of molecular accumulation in lymph nodes by lymphatic drug delivery system
    (The 79th Annual Meeting of the Japanese Cancer Association 2020)
  • Development of multiple metastatic lymph node model mice
    (The 79th Annual Meeting of the Japanese Cancer Association 2020)
  • Superselective local radiation therapy to treat metastatic lymph nodes in mice
    (The 79th Annual Meeting of the Japanese Cancer Association 2020)
  • Importance of drug osmotic pressure and viscosity for enhancing treatment effect using lymphatic drug delivery system
    (The 79th Annual Meeting of the Japanese Cancer Association 2020)
Professional career (2):
  • Ph.D.(Medicine) (Tohoku University)
  • PhD(Engineering) (Tohoku University)
Work history (8):
  • 2008 - Tohoku University Graduate School of Biomedical Engineering 教授
  • 2004 - Tohoku University Biomedical Engineering Research Organization 助教授
  • 2002 - Imperial College London Faculty of Medicine 研究員
  • 2000 - Department of Medicine, Harvard Medical School Brigham and Women's Hospital 研究員
  • 1998 - Department of Dermatology, Harvard Medical School Massachusetts General Hospital 講師
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Committee career (33):
  • 2014/10 - 現在 日本超音波医学会 工学フェロー
  • 2014/08 - 現在 日本DDS学会 評議員
  • 2014/01 - 現在 日本癌学会 評議員
  • 2009/04 - 現在 日本超音波医学会 東北地方会 運営委員会 運営委員
  • 2018/09 - Nature Reviews Materials 校閲委員
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Awards (23):
  • 2020/09 - The 60th Annual Meeting of The Japan Society of Ultrasonics in Medicine Encouragement Prize A study on the evaluation of treatment efficacy of metastatic lymph nodes associated with changes in drug osmotic pressure in the lymphatic drug delivery system
  • 2017/08/03 - 3rd Annual Data Science in Life Science and Engineering Collaboration and Symposium Oral Presentation 1st Place New insights on Lymph node metastasis : the benefit of using our mouse model in cancer metastasis
  • 2017/04/13 - 第76回日本医学放射線学会総会 CyPos賞 Silver medal Quantitative analysis of contrast-enhanced ultrasound for diagnosis of early lymph node metastasis of breast cancer.
  • 2016/10/01 - 第67回仙萩会総会 学術奨励賞 Direct Delivery of a Cytotoxic Anticancer Agent into the Metastatic Lymph Node Using Nano/Microbubbles and Ultrasound.
  • 2016/05/28 - 日本超音波医学会 第5回新人賞 ソノポレーションを利用したVasohibin-1 遺伝子導入による抗腫瘍効果の評価
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Association Membership(s) (5):
Japanese Society of Oral and Maxillofacial Surgeons ,  Japan Society of Ultrasonics in Medicine ,  Japan Society of Drug Delivery System ,  Japanese Cancer Association ,  Japan Society of Mechanical Engineers
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