Research field (3):
Pharmaceuticals - health and biochemistry
, Cell biology
, Functional biochemistry
Research keywords (3):
Biopharmaceutics
, Molecular Biology
, Glycotechnology
Research theme for competitive and other funds (11):
2022 - 2026 Development of novel drug screening system for neuroblastoma by elucidating the transcriptional activation mechanism of glycosyltransferase
2015 - 2018 Analysis of function and transcriptional mechanism of glycosyltransferase, which is associated with colon cancer, and development of novel drug screening system
2011 - 2013 Regulation of transcription factor suppresses malignant properties of cancer cells with changes in glycosylation
2010 - 2012 Molecular mechanism of the growth inhibition of normal cells withgalectin-3
2007 - 2008 Study on the network of transcription factors that regulate the galactosylation of N-glycans in cancer cells
2000 - 2001 Growth inhibition of tumor cells by transfection with β-1,4-glanctosyltransferase gene II or V.
1998 - 1999 新規β-1,4-ガラクトース転移酵素の機能の解析とその糖鎖生物学への応用
1998 - 1999 Analysis of cellular functions of cells transfected with sense or antisense β-1,4-galactosyltransferase cDNA
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Papers (50):
Kousuke Moriyama, Noe Inomoto, Hidetoshi Moriuchi, Masanobu Nihei, Miku Sato, Yoshiki Miyagi, Ayaka Tajiri, Takeshi Sato, Yasuhiko Tanaka, Yuuki Johno, et al. Characterization of enzyme-crosslinked albumin hydrogel for cell encapsulation. Journal of Bioscience and Bioengineering. 2023. 136. 6. 471-476
Masanobu Nihei, Saori Kawaguchi, Anri Mineyama, Takeshi Sato. Transcriptional Mechanism of the Mouse β4-Galactosyltransferase 6 Gene in Mouse Neuroblastoma Cell Line Neuro-2a. Biological and Pharmaceutical Bulletin. 2023. 46. 5. 741-745
Riho Tange, Ryuji Tachibana, Takeshi Sato. Phosphorylation of Specificity Protein 3 Is Critical for Activation of β4-Galactosyltransferase 3 Gene Promoter in SH-SY5Y Human Neuroblastoma Cell Line. Biological and Pharmaceutical Bulletin. 2021. 44. 4. 557-563
Alaa Fehaid, Ryo Fujii, Takeshi Sato, Akiyoshi Taniguchi. Silver Nanoparticles Affect the Inflammatory Response in a Lung Epithelial Cell Line. The Open Biotechnology Journal. 2020. 14. 1. 113-123