Art

J-GLOBAL ID：202002226077640596   Reference number：20A1608131

Suppression of Malignant Potentials of A549 Human Lung Cancer Cell Line by Downregulation of the β4-Galactosyltransferase 1 Gene Expression

β4-ガラクトシルトランスフェラーゼ1遺伝子発現の下方調節によるA549ヒト肺癌細胞株の悪性度の抑制

Author (4)： Kinouchi Saeka (Laboratory of Glycobiology, Department of Bioengineering, Nagaoka University of Technology) ,  Sato Miku (Laboratory of Glycobiology, Department of Bioengineering, Nagaoka University of Technology) ,  Furukawa Haruna (Laboratory of Glycobiology, Department of Bioengineering, Nagaoka University of Technology) ,  Sato Takeshi (Laboratory of Glycobiology, Department of Bioengineering, Nagaoka University of Technology)
Material： Biological and Pharmaceutical Bulletin (Web)
Volume： 43  Issue： 4  Page： 747-751(J-STAGE)  Publication year： 2020 
JST Material Number： U1402A  ISSN： 1347-5215  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： A549 cell ,...

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Author keywords (12)： β4-galactosyltransferase 1 ,  β4-galactosylation ,  N-glycan ,  lung cancer ,  malignant potential ,  mitogen-activated protein kinase ,  β4-galactosyltransferase 1 ,  β4-galactosylation ,  N-glycan ,  lung cancer ,  malignant potential ,  mitogen-activated protein kinase

JST classification (4)： Biological function  (EB03040U) ,  Biological function  (EB06020T) ,  Gene expression  (EC02040Q) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (28)：

• 1) Hart IR, Saini A. Biology of tumour metastasis. Lancet, 339, 1453-1457 (1992).
• 2) Franks LM. What is cancer? Introduction to the Cellular and Molecular Biology of Cancer. (Franks LM, Teich NM eds.) Oxford University Press, Oxford, pp. 1-20 (1997).
• 3) Guo HB, Lee I, Kamar M, Pierce M. N-Acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways. J. Biol. Chem., 278, 52412-52424 (2003).
• 4) Christiansen MN, Chik J, Lee L, Anugraham M, Abrahams JL, Packer NH. Cell surface protein glycosylation in cancer. Proteomics, 14, 525-546 (2014).
• 5) Safe S, Abdelrahim M. Sp transcription factor family and its role in cancer. Eur. J. Cancer, 41, 2438-2448 (2005).

Terms in the title (8)： ガラクトシルトランスフェラーゼ ,  遺伝子発現 ,  下方調節 ,  A549 ,  ヒト ,  肺癌 ,  細胞株 ,  悪性度